53 items (Penicillium solitum) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

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protein homology

Your Input:
	A0A1V6RKE0	Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (762 aa)
	A0A1V6PLK7	Uncharacterized protein. (45 aa)
	A0A1V6Q6F3	CUE domain-containing protein. (701 aa)
	A0A1V6QFA0	Acyl_transf_3 domain-containing protein. (481 aa)
	A0A1V6QG88	HTH TFE/IIEalpha-type domain-containing protein. (450 aa)
	A0A1V6QJX0	WD_REPEATS_REGION domain-containing protein. (197 aa)
	A0A1V6QLN9	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (240 aa)
	A0A1V6QN45	Helicase ATP-binding domain-containing protein. (795 aa)
	A0A1V6QQE8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (404 aa)
	A0A1V6QQN2	Uncharacterized protein. (361 aa)
	A0A1V6QRV0	Uncharacterized protein. (364 aa)
	A0A1V6QS22	Uncharacterized protein. (944 aa)
	A0A1V6QSL3	BHLH domain-containing protein. (428 aa)
	A0A1V6QTW7	Uncharacterized protein. (822 aa)
	A0A1V6QU33	Uncharacterized protein. (293 aa)
	A0A1V6QU85	Uncharacterized protein. (371 aa)
	A0A1V6QUJ6	Acyl_transf_3 domain-containing protein. (457 aa)
	A0A1V6QVJ6	TFIID_20kDa domain-containing protein. (624 aa)
	A0A1V6QW10	BTP domain-containing protein. (215 aa)
	A0A1V6QWJ8	TAFII55_N domain-containing protein. (478 aa)
	A0A1V6QWP1	Helicase ATP-binding domain-containing protein. (392 aa)
	A0A1V6QWW8	Uncharacterized protein. (290 aa)
	A0A1V6QX82	DUF4211 domain-containing protein. (638 aa)
	A0A1V6QXW5	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (480 aa)
	A0A1V6QYB7	Uncharacterized protein. (1243 aa)
	A0A1V6R0C5	HMG box domain-containing protein. (513 aa)
	A0A1V6R463	Uncharacterized protein. (377 aa)
	A0A1V6R4C6	Uncharacterized protein. (365 aa)
	A0A1V6R4F3	Uncharacterized protein. (275 aa)
	A0A1V6R597	Uncharacterized protein. (343 aa)
	A0A1V6R5U6	Uncharacterized protein. (777 aa)
	A0A1V6R625	Uncharacterized protein. (72 aa)
	A0A1V6R753	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (691 aa)
	A0A1V6R809	CBFD_NFYB_HMF domain-containing protein. (212 aa)
	A0A1V6R8A4	BZIP domain-containing protein. (509 aa)
	A0A1V6R8W4	Uncharacterized protein. (858 aa)
	A0A1V6R963	CYCLIN domain-containing protein; Belongs to the cyclin family. (428 aa)
	A0A1V6RB60	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (447 aa)
	A0A1V6RCP8	Uncharacterized protein. (1205 aa)
	A0A1V6RHQ4	TAFII28 domain-containing protein. (382 aa)
	A0A1V6RIT2	Acyl_transf_3 domain-containing protein. (474 aa)
	A0A1V6RJ00	TAF domain-containing protein. (442 aa)
	A0A1V6RJ20	BSD domain-containing protein. (651 aa)
	A0A1V6RK15	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (293 aa)
	A0A1V6RLR3	CBFD_NFYB_HMF domain-containing protein. (209 aa)
	A0A1V6RM36	RING-type domain-containing protein. (370 aa)
	A0A1V6RP94	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (111 aa)
	A0A1V6RPZ1	Uncharacterized protein. (374 aa)
	A0A1V6RQ03	DUF3591 domain-containing protein. (1116 aa)
	A0A1V6RQ23	BZIP domain-containing protein. (297 aa)
	A0A1V6RQQ3	Uncharacterized protein. (749 aa)
	A0A1V6RQS9	Uncharacterized protein. (1270 aa)
	A0A1V6RR36	Uncharacterized protein. (541 aa)

Your Current Organism:

Penicillium solitum

NCBI taxonomy Id: 60172
Other names: ATCC 9923, CBS 288.36, CBS 424.89, FRR 937, IBT 3948, IFO 7765, IMI 039810, IMI 092225, LSHB P52, MUCL 28668, MUCL 29173, NRRL 937, P. solitum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V6PLK7	A0A1V6QG88	Uncharacterized protein.	HTH TFE/IIEalpha-type domain-containing protein.	0.851
A0A1V6PLK7	A0A1V6QJX0	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.872
A0A1V6PLK7	A0A1V6QLN9	Uncharacterized protein.	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...]	0.926
A0A1V6PLK7	A0A1V6QN45	Uncharacterized protein.	Helicase ATP-binding domain-containing protein.	0.813
A0A1V6PLK7	A0A1V6QQE8	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.783
A0A1V6PLK7	A0A1V6QRV0	Uncharacterized protein.	Uncharacterized protein.	0.842
A0A1V6PLK7	A0A1V6QTW7	Uncharacterized protein.	Uncharacterized protein.	0.814
A0A1V6PLK7	A0A1V6QU33	Uncharacterized protein.	Uncharacterized protein.	0.923
A0A1V6PLK7	A0A1V6QU85	Uncharacterized protein.	Uncharacterized protein.	0.831
A0A1V6PLK7	A0A1V6QVJ6	Uncharacterized protein.	TFIID_20kDa domain-containing protein.	0.923
A0A1V6PLK7	A0A1V6QW10	Uncharacterized protein.	BTP domain-containing protein.	0.582
A0A1V6PLK7	A0A1V6QWJ8	Uncharacterized protein.	TAFII55_N domain-containing protein.	0.915
A0A1V6PLK7	A0A1V6QX82	Uncharacterized protein.	DUF4211 domain-containing protein.	0.827
A0A1V6PLK7	A0A1V6QXW5	Uncharacterized protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.813
A0A1V6PLK7	A0A1V6QYB7	Uncharacterized protein.	Uncharacterized protein.	0.923
A0A1V6PLK7	A0A1V6R463	Uncharacterized protein.	Uncharacterized protein.	0.814
A0A1V6PLK7	A0A1V6R4C6	Uncharacterized protein.	Uncharacterized protein.	0.923
A0A1V6PLK7	A0A1V6R4F3	Uncharacterized protein.	Uncharacterized protein.	0.827
A0A1V6PLK7	A0A1V6R597	Uncharacterized protein.	Uncharacterized protein.	0.923
A0A1V6PLK7	A0A1V6R753	Uncharacterized protein.	Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family.	0.850

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