(122 nodes) Lysine degradation network (Penicillium solitum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V6Q3B8	SET domain-containing protein. (382 aa)
	A0A1V6Q7H6	Uncharacterized protein. (383 aa)
	A0A1V6Q8M0	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
	A0A1V6Q9L4	Uncharacterized protein. (414 aa)
	A0A1V6QCF9	SET domain-containing protein. (662 aa)
	A0A1V6QCU1	Fungal_trans domain-containing protein. (491 aa)
	A0A1V6QCW2	Uncharacterized protein. (432 aa)
	A0A1V6QFL4	Uncharacterized protein. (660 aa)
	A0A1V6QG49	Aldedh domain-containing protein. (200 aa)
	A0A1V6QG66	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (499 aa)
	A0A1V6QG81	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
	A0A1V6QH18	Aldedh domain-containing protein. (467 aa)
	A0A1V6QHB1	Dihydrolipoyl dehydrogenase. (512 aa)
	A0A1V6QJ15	Uncharacterized protein. (143 aa)
	A0A1V6QJ64	Succinate-semialdehyde dehydrogenase. (493 aa)
	A0A1V6QJS1	Uncharacterized protein. (733 aa)
	A0A1V6QLP8	MHYT domain-containing protein. (740 aa)
	A0A1V6QMD7	Uncharacterized protein. (495 aa)
	A0A1V6QQP0	Uncharacterized protein. (305 aa)
	A0A1V6QQY0	Lipoyl-binding domain-containing protein. (460 aa)
	A0A1V6QR03	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	A0A1V6QR42	TauD domain-containing protein. (397 aa)
	A0A1V6QRE7	SET domain-containing protein. (959 aa)
	A0A1V6QRT0	Uncharacterized protein. (404 aa)
	A0A1V6QS93	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (495 aa)
	A0A1V6QSC7	DAO domain-containing protein. (435 aa)
	A0A1V6QSN4	DAO domain-containing protein. (480 aa)
	A0A1V6QSQ0	Uncharacterized protein. (814 aa)
	A0A1V6QSV7	Uncharacterized protein. (175 aa)
	A0A1V6QT42	AB hydrolase-1 domain-containing protein. (553 aa)
	A0A1V6QTL2	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	A0A1V6QU28	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	A0A1V6QUB8	DAO domain-containing protein. (437 aa)
	A0A1V6QUG2	SET domain-containing protein. (131 aa)
	A0A1V6QUW0	Fibronectin type-III domain-containing protein. (1053 aa)
	A0A1V6QV06	Uncharacterized protein. (424 aa)
	A0A1V6QVP4	Uncharacterized protein. (794 aa)
	A0A1V6QVW9	Uncharacterized protein. (496 aa)
	A0A1V6QVY9	Uncharacterized protein. (173 aa)
	A0A1V6QW31	Zn(2)-C6 fungal-type domain-containing protein. (812 aa)
	A0A1V6QWB6	Uncharacterized protein. (541 aa)
	A0A1V6QWI7	PHD-type domain-containing protein. (837 aa)
	A0A1V6QWU1	Uncharacterized protein. (395 aa)
	A0A1V6QWY2	Uncharacterized protein. (316 aa)
	A0A1V6QX01	DAO domain-containing protein. (440 aa)
	A0A1V6QX60	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
	A0A1V6QXF2	Uncharacterized protein. (369 aa)
	A0A1V6QXG2	Uncharacterized protein. (328 aa)
	A0A1V6QXG8	Aldedh domain-containing protein. (499 aa)
	A0A1V6QZ09	MYND-type domain-containing protein. (232 aa)
	A0A1V6QZ12	Uncharacterized protein. (342 aa)
	A0A1V6QZ71	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (514 aa)
	A0A1V6QZ93	Succinate-semialdehyde dehydrogenase. (498 aa)
	A0A1V6QZP8	DAO domain-containing protein. (431 aa)
	A0A1V6QZU5	Uncharacterized protein. (188 aa)
	A0A1V6R042	Uncharacterized protein. (449 aa)
	A0A1V6R092	Fungal_trans domain-containing protein. (406 aa)
	A0A1V6R0G7	Uncharacterized protein. (260 aa)
	A0A1V6R0R3	SET domain-containing protein. (456 aa)
	A0A1V6R0X1	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	A0A1V6R1B8	Uncharacterized protein. (335 aa)
	A0A1V6R1N6	Uncharacterized protein. (321 aa)
	A0A1V6R2B0	Protein kinase domain-containing protein. (905 aa)
	A0A1V6R2X2	Zn(2)-C6 fungal-type domain-containing protein. (1064 aa)
	A0A1V6R343	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (884 aa)
	A0A1V6R363	MYND-type domain-containing protein. (497 aa)
	A0A1V6R3Q1	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones. (505 aa)
	A0A1V6R3R2	SET domain-containing protein. (617 aa)
	A0A1V6R450	Uncharacterized protein. (400 aa)
	A0A1V6R4D8	Uncharacterized protein. (257 aa)
	A0A1V6R5P3	Aldedh domain-containing protein. (499 aa)
	A0A1V6R6D1	SANT domain-containing protein. (847 aa)
	A0A1V6R6T8	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (293 aa)
	A0A1V6R7C7	Uncharacterized protein. (204 aa)
	A0A1V6R7E7	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. (1210 aa)
	A0A1V6R7V8	Fungal_trans domain-containing protein. (595 aa)
	A0A1V6R855	Uncharacterized protein. (459 aa)
	A0A1V6R9I0	Lipoyl-binding domain-containing protein. (456 aa)
	A0A1V6R9W6	Uncharacterized protein. (252 aa)
	A0A1V6RAS9	Uncharacterized protein. (215 aa)
	A0A1V6RB48	Uncharacterized protein. (353 aa)
	A0A1V6RB55	Fungal_trans domain-containing protein. (484 aa)
	A0A1V6RB75	Uncharacterized protein. (440 aa)
	A0A1V6RBZ5	Uncharacterized protein. (384 aa)
	A0A1V6RC97	Zn(2)-C6 fungal-type domain-containing protein. (672 aa)
	A0A1V6RCG2	Uncharacterized protein. (465 aa)
	A0A1V6RDC5	Uncharacterized protein. (500 aa)
	A0A1V6RGF6	Uncharacterized protein. (744 aa)
	A0A1V6RGL5	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (502 aa)
	A0A1V6RHK4	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (493 aa)
	A0A1V6RHV0	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (482 aa)
	A0A1V6RI84	Uncharacterized protein. (295 aa)
	A0A1V6RI85	AB hydrolase-1 domain-containing protein. (528 aa)
	A0A1V6RIB0	DAO domain-containing protein. (382 aa)
	A0A1V6RIM5	Uncharacterized protein. (360 aa)
	A0A1V6RIP6	PHD domain-containing protein. (674 aa)
	A0A1V6RIS9	SET domain-containing protein. (435 aa)
	A0A1V6RIX6	Uncharacterized protein. (312 aa)
	A0A1V6RJ16	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (483 aa)
	A0A1V6RJ84	Uncharacterized protein. (1013 aa)
	A0A1V6RJA3	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (465 aa)
	A0A1V6RJQ1	Uncharacterized protein. (520 aa)
	A0A1V6RK17	Zn(2)-C6 fungal-type domain-containing protein. (626 aa)
	A0A1V6RKU8	SET domain-containing protein. (351 aa)
	A0A1V6RLG3	Succinate-semialdehyde dehydrogenase. (532 aa)
	A0A1V6RLR6	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
	A0A1V6RLS4	SET domain-containing protein. (174 aa)
	A0A1V6RND8	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Belongs to the AlaDH/PNT family. (375 aa)
	A0A1V6RNG8	Uncharacterized protein. (412 aa)
	A0A1V6RNJ2	Zn(2)-C6 fungal-type domain-containing protein. (730 aa)
	A0A1V6RNV9	Uncharacterized protein. (273 aa)
	A0A1V6RP35	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (516 aa)
	A0A1V6RPD3	Uncharacterized protein. (532 aa)
	A0A1V6RPS8	DAO domain-containing protein. (438 aa)
	A0A1V6RQ98	Uncharacterized protein. (274 aa)
	A0A1V6RQB1	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (479 aa)
	A0A1V6RQI2	Uncharacterized protein. (322 aa)
	A0A1V6RQL7	Zn(2)-C6 fungal-type domain-containing protein. (476 aa)
	A0A1V6RQT0	Uncharacterized protein. (383 aa)
	A0A1V6RR24	Fungal_trans domain-containing protein. (573 aa)
	A0A1V6RR41	Uncharacterized protein. (710 aa)
	A0A1V6RRL7	Aldedh domain-containing protein. (496 aa)

Your Current Organism:

Penicillium solitum

NCBI taxonomy Id: 60172
Other names: ATCC 9923, CBS 288.36, CBS 424.89, FRR 937, IBT 3948, IFO 7765, IMI 039810, IMI 092225, LSHB P52, MUCL 28668, MUCL 29173, NRRL 937, P. solitum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V6Q3B8	A0A1V6QCF9	SET domain-containing protein.	SET domain-containing protein.	0.694
A0A1V6Q3B8	A0A1V6QMD7	SET domain-containing protein.	Uncharacterized protein.	0.499
A0A1V6Q3B8	A0A1V6QRE7	SET domain-containing protein.	SET domain-containing protein.	0.792
A0A1V6Q3B8	A0A1V6QSQ0	SET domain-containing protein.	Uncharacterized protein.	0.499
A0A1V6Q3B8	A0A1V6QUG2	SET domain-containing protein.	SET domain-containing protein.	0.514
A0A1V6Q3B8	A0A1V6QVP4	SET domain-containing protein.	Uncharacterized protein.	0.640
A0A1V6Q3B8	A0A1V6QWI7	SET domain-containing protein.	PHD-type domain-containing protein.	0.585
A0A1V6Q3B8	A0A1V6QWY2	SET domain-containing protein.	Uncharacterized protein.	0.585
A0A1V6Q3B8	A0A1V6R0R3	SET domain-containing protein.	SET domain-containing protein.	0.514
A0A1V6Q3B8	A0A1V6R343	SET domain-containing protein.	Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.	0.699
A0A1V6Q3B8	A0A1V6R3Q1	SET domain-containing protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.	0.776
A0A1V6Q3B8	A0A1V6R7E7	SET domain-containing protein.	Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation.	0.681
A0A1V6Q3B8	A0A1V6RI84	SET domain-containing protein.	Uncharacterized protein.	0.506
A0A1V6Q3B8	A0A1V6RIP6	SET domain-containing protein.	PHD domain-containing protein.	0.585
A0A1V6Q3B8	A0A1V6RKU8	SET domain-containing protein.	SET domain-containing protein.	0.499
A0A1V6Q3B8	A0A1V6RLS4	SET domain-containing protein.	SET domain-containing protein.	0.514
A0A1V6Q8M0	A0A1V6QHB1	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Dihydrolipoyl dehydrogenase.	0.538
A0A1V6Q8M0	A0A1V6QQY0	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Lipoyl-binding domain-containing protein.	0.415
A0A1V6Q8M0	A0A1V6QXG8	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Aldedh domain-containing protein.	0.534
A0A1V6Q8M0	A0A1V6R5P3	Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family.	Aldedh domain-containing protein.	0.534

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