(83 nodes) Propanoate metabolism network (Penicillium solitum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1V6Q4M0	Uncharacterized protein. (559 aa)
	A0A1V6Q8I3	Uncharacterized protein. (94 aa)
	A0A1V6Q8N3	Uncharacterized protein. (350 aa)
	A0A1V6QCC8	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (695 aa)
	A0A1V6QFF4	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (448 aa)
	A0A1V6QFL4	Uncharacterized protein. (660 aa)
	A0A1V6QG58	Uncharacterized protein. (353 aa)
	A0A1V6QG81	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
	A0A1V6QHB1	Dihydrolipoyl dehydrogenase. (512 aa)
	A0A1V6QJ21	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
	A0A1V6QLI3	Epimerase domain-containing protein. (334 aa)
	A0A1V6QLL1	Uncharacterized protein. (272 aa)
	A0A1V6QM43	Uncharacterized protein. (469 aa)
	A0A1V6QMA1	Uncharacterized protein. (350 aa)
	A0A1V6QN61	Uncharacterized protein. (357 aa)
	A0A1V6QQ66	Epimerase domain-containing protein. (341 aa)
	A0A1V6QQC6	Uncharacterized protein. (700 aa)
	A0A1V6QQU5	Pyr_redox_2 domain-containing protein. (308 aa)
	A0A1V6QR03	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
	A0A1V6QRK5	Uncharacterized protein. (347 aa)
	A0A1V6QRM1	Uncharacterized protein. (167 aa)
	A0A1V6QRQ3	Epimerase domain-containing protein. (315 aa)
	A0A1V6QSD8	Uncharacterized protein. (341 aa)
	A0A1V6QSN0	Uncharacterized protein. (401 aa)
	A0A1V6QSR8	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (498 aa)
	A0A1V6QT18	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (693 aa)
	A0A1V6QT42	AB hydrolase-1 domain-containing protein. (553 aa)
	A0A1V6QTR9	Uncharacterized protein. (2273 aa)
	A0A1V6QU34	Uncharacterized protein. (427 aa)
	A0A1V6QUK0	CoA_binding domain-containing protein. (676 aa)
	A0A1V6QVK9	SET domain-containing protein. (428 aa)
	A0A1V6QVY1	3Beta_HSD domain-containing protein. (347 aa)
	A0A1V6QVY4	Epimerase domain-containing protein. (342 aa)
	A0A1V6QW85	ADH_N domain-containing protein. (431 aa)
	A0A1V6QWA4	Epimerase domain-containing protein. (360 aa)
	A0A1V6QWX7	Uncharacterized protein. (244 aa)
	A0A1V6QXV1	MaoC-like domain-containing protein. (901 aa)
	A0A1V6QY22	Epimerase domain-containing protein. (336 aa)
	A0A1V6QY98	Succinate-CoA ligase subunit beta. (414 aa)
	A0A1V6QYA1	Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (443 aa)
	A0A1V6QYI2	Uncharacterized protein. (346 aa)
	A0A1V6R0A7	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (480 aa)
	A0A1V6R0Y0	PKS_ER domain-containing protein. (352 aa)
	A0A1V6R152	Uncharacterized protein. (494 aa)
	A0A1V6R1Q8	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (473 aa)
	A0A1V6R2I6	Uncharacterized protein. (385 aa)
	A0A1V6R532	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (689 aa)
	A0A1V6R6T8	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family. (293 aa)
	A0A1V6R7B6	Uncharacterized protein. (287 aa)
	A0A1V6R7Z7	Uncharacterized protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (450 aa)
	A0A1V6R896	Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (329 aa)
	A0A1V6R8G4	Uncharacterized protein. (571 aa)
	A0A1V6R8K7	ADH_N domain-containing protein. (447 aa)
	A0A1V6R8W5	Uncharacterized protein. (350 aa)
	A0A1V6R9K6	Uncharacterized protein. (334 aa)
	A0A1V6R9Y8	Aldedh domain-containing protein. (516 aa)
	A0A1V6RA76	Uncharacterized protein. (360 aa)
	A0A1V6RAJ3	Uncharacterized protein. (548 aa)
	A0A1V6RAU8	Uncharacterized protein. (198 aa)
	A0A1V6RBI5	Uncharacterized protein. (418 aa)
	A0A1V6RCE2	Uncharacterized protein. (563 aa)
	A0A1V6RCK6	Uncharacterized protein. (671 aa)
	A0A1V6RD64	Acetyl-coenzyme A synthetase. (669 aa)
	A0A1V6RDF3	Uncharacterized protein. (172 aa)
	A0A1V6RGF7	Uncharacterized protein. (350 aa)
	A0A1V6RGU9	Uncharacterized protein. (305 aa)
	A0A1V6RHA6	Uncharacterized protein. (221 aa)
	A0A1V6RHE2	Epimerase domain-containing protein. (340 aa)
	A0A1V6RI64	Uncharacterized protein. (552 aa)
	A0A1V6RK16	Uncharacterized protein. (1464 aa)
	A0A1V6RKC4	ADH_N domain-containing protein. (381 aa)
	A0A1V6RL14	Aldedh domain-containing protein. (588 aa)
	A0A1V6RLR6	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
	A0A1V6RNV9	Uncharacterized protein. (273 aa)
	A0A1V6RPP9	Epimerase domain-containing protein. (328 aa)
	A0A1V6RQ35	Uncharacterized protein. (326 aa)
	A0A1V6RQ84	Uncharacterized protein. (489 aa)
	A0A1V6RQ97	Transket_pyr domain-containing protein. (387 aa)
	A0A1V6RQD0	Uncharacterized protein. (623 aa)
	A0A1V6RQH0	Uncharacterized protein. (90 aa)
	A0A1V6RQP5	Probable acetate kinase. (389 aa)
	A0A1V6RQU3	Uncharacterized protein. (312 aa)
	A0A1V6RQX0	Uncharacterized protein. (2014 aa)

Your Current Organism:

Penicillium solitum

NCBI taxonomy Id: 60172
Other names: ATCC 9923, CBS 288.36, CBS 424.89, FRR 937, IBT 3948, IFO 7765, IMI 039810, IMI 092225, LSHB P52, MUCL 28668, MUCL 29173, NRRL 937, P. solitum

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1V6Q4M0	A0A1V6QCC8	Uncharacterized protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.532
A0A1V6Q4M0	A0A1V6QFF4	Uncharacterized protein.	2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).	0.583
A0A1V6Q4M0	A0A1V6QFL4	Uncharacterized protein.	Uncharacterized protein.	0.707
A0A1V6Q4M0	A0A1V6QG81	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.707
A0A1V6Q4M0	A0A1V6QHB1	Uncharacterized protein.	Dihydrolipoyl dehydrogenase.	0.504
A0A1V6Q4M0	A0A1V6QLL1	Uncharacterized protein.	Uncharacterized protein.	0.768
A0A1V6Q4M0	A0A1V6QQC6	Uncharacterized protein.	Uncharacterized protein.	0.622
A0A1V6Q4M0	A0A1V6QQU5	Uncharacterized protein.	Pyr_redox_2 domain-containing protein.	0.591
A0A1V6Q4M0	A0A1V6QR03	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.707
A0A1V6Q4M0	A0A1V6QRM1	Uncharacterized protein.	Uncharacterized protein.	0.532
A0A1V6Q4M0	A0A1V6QT18	Uncharacterized protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.532
A0A1V6Q4M0	A0A1V6QT42	Uncharacterized protein.	AB hydrolase-1 domain-containing protein.	0.540
A0A1V6Q4M0	A0A1V6QTR9	Uncharacterized protein.	Uncharacterized protein.	0.571
A0A1V6Q4M0	A0A1V6QUK0	Uncharacterized protein.	CoA_binding domain-containing protein.	0.557
A0A1V6Q4M0	A0A1V6QXV1	Uncharacterized protein.	MaoC-like domain-containing protein.	0.768
A0A1V6Q4M0	A0A1V6R0A7	Uncharacterized protein.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.677
A0A1V6Q4M0	A0A1V6R1Q8	Uncharacterized protein.	3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.	0.679
A0A1V6Q4M0	A0A1V6R532	Uncharacterized protein.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.532
A0A1V6Q4M0	A0A1V6R6T8	Uncharacterized protein.	Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.	0.826
A0A1V6Q4M0	A0A1V6R7B6	Uncharacterized protein.	Uncharacterized protein.	0.768

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