(87 nodes) Ribosome biogenesis in eukaryotes network (Aspergillus carbonarius)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A1R3R615	Protein kish; Involved in the early part of the secretory pathway. Belongs to the KISH family. (83 aa)
	A0A1R3S385	Uncharacterized protein. (530 aa)
	A0A1R3S383	Uncharacterized protein. (732 aa)
	A0A1R3S380	Importin N-terminal domain-containing protein. (1072 aa)
	A0A1R3S372	Uncharacterized protein; Belongs to the complex I LYR family. (139 aa)
	A0A1R3S306	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (265 aa)
	A0A1R3S2R4	CP-type G domain-containing protein. (540 aa)
	A0A1R3S2F2	RNase III domain-containing protein. (608 aa)
	A0A1R3S251	Brix domain-containing protein. (297 aa)
	A0A1R3S1U6	Ribosomal_L7Ae domain-containing protein. (234 aa)
	A0A1R3S1J4	Uncharacterized protein. (346 aa)
	A0A1R3S1B8	BP28CT domain-containing protein. (1799 aa)
	A0A1R3S1A2	GTP-binding nuclear protein; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (213 aa)
	A0A1R3RZS4	Nop domain-containing protein. (515 aa)
	A0A1R3RZP1	Exonuclease domain-containing protein. (659 aa)
	A0A1R3RZE8	Exonuclease domain-containing protein. (187 aa)
	A0A1R3RYW7	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (654 aa)
	A0A1R3RYN3	Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (560 aa)
	A0A1R3RYM1	Uncharacterized protein. (552 aa)
	A0A1R3RXP9	Uncharacterized protein. (288 aa)
	A0A1R3RXL1	Uncharacterized protein. (215 aa)
	A0A1R3RXI9	Uncharacterized protein. (200 aa)
	A0A1R3RXD9	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (122 aa)
	A0A1R3RX60	C2H2-type domain-containing protein. (436 aa)
	A0A1R3RX23	Uncharacterized protein. (281 aa)
	A0A1R3RWX7	C2H2-type domain-containing protein. (400 aa)
	A0A1R3RVP4	Uncharacterized protein. (259 aa)
	A0A1R3RVL9	U3 small nucleolar RNA-associated protein 22. (1110 aa)
	A0A1R3RVA7	Uncharacterized protein. (476 aa)
	A0A1R3RV78	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (526 aa)
	A0A1R3RU63	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (561 aa)
	A0A1R3RTQ7	NTF2 domain-containing protein. (161 aa)
	A0A1R3RTQ1	WD_REPEATS_REGION domain-containing protein. (976 aa)
	A0A1R3RTD4	Zn(2)-C6 fungal-type domain-containing protein. (747 aa)
	A0A1R3RTB8	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (329 aa)
	A0A1R3RT89	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (662 aa)
	A0A1R3RT69	Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (347 aa)
	A0A1R3RT57	U3 small nucleolar ribonucleoprotein protein MPP10; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the MPP10 family. (701 aa)
	A0A1R3RS48	Uncharacterized protein. (668 aa)
	NAT10	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1068 aa)
	A0A1R3RRL0	Kri1_C domain-containing protein. (614 aa)
	A0A1R3RQQ9	Zn(2)-C6 fungal-type domain-containing protein. (708 aa)
	A0A1R3RQA1	Uncharacterized protein. (270 aa)
	A0A1R3RQ90	Uncharacterized protein. (393 aa)
	A0A1R3RPF8	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (335 aa)
	A0A1R3RPD4	Uncharacterized protein. (301 aa)
	A0A1R3RNL3	WD_REPEATS_REGION domain-containing protein. (952 aa)
	A0A1R3RN71	WD_REPEATS_REGION domain-containing protein. (962 aa)
	A0A1R3RN68	Uncharacterized protein. (215 aa)
	A0A1R3RMP5	Uncharacterized protein. (393 aa)
	A0A1R3RL47	H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (274 aa)
	A0A1R3RJJ8	WD_REPEATS_REGION domain-containing protein. (543 aa)
	A0A1R3RJF4	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (370 aa)
	A0A1R3RJE2	Ribonuclease P protein subunit. (252 aa)
	A0A1R3RJC0	TruB_N domain-containing protein. (407 aa)
	A0A1R3RJ63	Uncharacterized protein. (160 aa)
	A0A1R3RIZ9	WD_REPEATS_REGION domain-containing protein. (1036 aa)
	A0A1R3RIV0	Uncharacterized protein. (118 aa)
	A0A1R3RIN2	WD_REPEATS_REGION domain-containing protein. (901 aa)
	A0A1R3RI70	Fe2OG dioxygenase domain-containing protein; Belongs to the iron/ascorbate-dependent oxidoreductase family. (365 aa)
	A0A1R3RHM0	RNase III domain-containing protein. (154 aa)
	A0A1R3RG48	Uncharacterized protein. (877 aa)
	A0A1R3RFV3	Uncharacterized protein. (551 aa)
	A0A1R3RF58	PINc domain-containing protein. (189 aa)
	A0A1R3RF41	DUF4604 domain-containing protein. (164 aa)
	A0A1R3RF39	Tr-type G domain-containing protein. (1077 aa)
	A0A1R3RDK9	Uncharacterized protein. (313 aa)
	A0A1R3RD38	S4 RNA-binding domain-containing protein. (188 aa)
	A0A1R3RCR5	Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (177 aa)
	A0A1R3RCP5	PUA domain-containing protein. (487 aa)
	TIF6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export; Belongs to the eIF-6 family. (247 aa)
	A0A1R3RCH6	CP-type G domain-containing protein. (671 aa)
	A0A1R3RCH5	Uncharacterized protein. (147 aa)
	A0A1R3RCG3	Uncharacterized protein. (131 aa)
	A0A1R3RAZ0	Spindle pole body component. (796 aa)
	A0A1R3RAN0	Exonuclease domain-containing protein. (708 aa)
	A0A1R3RA75	Rieske domain-containing protein. (464 aa)
	A0A1R3R9V2	Uncharacterized protein; Belongs to the AAA ATPase family. (566 aa)
	A0A1R3R9N3	GAR domain-containing protein. (1169 aa)
	A0A1R3R9F0	RAI1 domain-containing protein. (368 aa)
	A0A1R3R9B3	Fcf2 domain-containing protein. (239 aa)
	A0A1R3R986	WD_REPEATS_REGION domain-containing protein. (928 aa)
	A0A1R3R966	Uncharacterized protein. (303 aa)
	A0A1R3R8I8	WD_REPEATS_REGION domain-containing protein. (603 aa)
	A0A1R3R8I3	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (125 aa)
	A0A1R3R7G9	Uncharacterized protein. (405 aa)
	A0A1R3R5W1	RNase III domain-containing protein. (230 aa)

Your Current Organism:

Aspergillus carbonarius

NCBI taxonomy Id: 602072
Other names: A. carbonarius ITEM 5010, Aspergillus carbonarius ITEM 5010

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1R3R5W1	A0A1R3R7G9	A0A1R3R5W1	A0A1R3R7G9	RNase III domain-containing protein.	Uncharacterized protein.	0.454
A0A1R3R5W1	A0A1R3R8I3	A0A1R3R5W1	A0A1R3R8I3	RNase III domain-containing protein.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.411
A0A1R3R5W1	A0A1R3RCH6	A0A1R3R5W1	A0A1R3RCH6	RNase III domain-containing protein.	CP-type G domain-containing protein.	0.560
A0A1R3R5W1	A0A1R3RD38	A0A1R3R5W1	A0A1R3RD38	RNase III domain-containing protein.	S4 RNA-binding domain-containing protein.	0.631
A0A1R3R5W1	A0A1R3RF39	A0A1R3R5W1	A0A1R3RF39	RNase III domain-containing protein.	Tr-type G domain-containing protein.	0.444
A0A1R3R5W1	A0A1R3RTQ1	A0A1R3R5W1	A0A1R3RTQ1	RNase III domain-containing protein.	WD_REPEATS_REGION domain-containing protein.	0.428
A0A1R3R5W1	A0A1R3RU63	A0A1R3R5W1	A0A1R3RU63	RNase III domain-containing protein.	Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily.	0.589
A0A1R3R5W1	A0A1R3RXD9	A0A1R3R5W1	A0A1R3RXD9	RNase III domain-containing protein.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.411
A0A1R3R5W1	A0A1R3RYW7	A0A1R3R5W1	A0A1R3RYW7	RNase III domain-containing protein.	Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily.	0.496
A0A1R3R5W1	A0A1R3S2R4	A0A1R3R5W1	A0A1R3S2R4	RNase III domain-containing protein.	CP-type G domain-containing protein.	0.562
A0A1R3R5W1	A0A1R3S380	A0A1R3R5W1	A0A1R3S380	RNase III domain-containing protein.	Importin N-terminal domain-containing protein.	0.553
A0A1R3R5W1	NAT10	A0A1R3R5W1	A0A1R3RS46	RNase III domain-containing protein.	RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.	0.467
A0A1R3R615	A0A1R3RVA7	A0A1R3R615	A0A1R3RVA7	Protein kish; Involved in the early part of the secretory pathway. Belongs to the KISH family.	Uncharacterized protein.	0.679
A0A1R3R615	A0A1R3RXI9	A0A1R3R615	A0A1R3RXI9	Protein kish; Involved in the early part of the secretory pathway. Belongs to the KISH family.	Uncharacterized protein.	0.607
A0A1R3R7G9	A0A1R3R5W1	A0A1R3R7G9	A0A1R3R5W1	Uncharacterized protein.	RNase III domain-containing protein.	0.454
A0A1R3R7G9	A0A1R3R8I3	A0A1R3R7G9	A0A1R3R8I3	Uncharacterized protein.	Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family.	0.929
A0A1R3R7G9	A0A1R3R8I8	A0A1R3R7G9	A0A1R3R8I8	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.998
A0A1R3R7G9	A0A1R3R966	A0A1R3R7G9	A0A1R3R966	Uncharacterized protein.	Uncharacterized protein.	0.994
A0A1R3R7G9	A0A1R3R986	A0A1R3R7G9	A0A1R3R986	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.995
A0A1R3R7G9	A0A1R3R9B3	A0A1R3R7G9	A0A1R3R9B3	Uncharacterized protein.	Fcf2 domain-containing protein.	0.986