STRINGSTRING
TFAP2A TFAP2A CTSL CTSL PIP PIP TRPM8 TRPM8 KLK2 KLK2 KLK7 KLK7 KLK11 KLK11 SCARB1 SCARB1 S100A4 S100A4 IL11 IL11 VTCN1 VTCN1 F3 F3 PLA2G2A PLA2G2A SDF4 SDF4 PIN4 PIN4 NOG NOG TLR2 TLR2 RNASE1 RNASE1 ENSCSAP00000017662 ENSCSAP00000017662 TLR5 TLR5 LOC103230436 LOC103230436 LIG4 LIG4 HDGFL1 HDGFL1 OR51E2 OR51E2 ANXA2 ANXA2 ADRB2 ADRB2 ENSCSAP00000000063 ENSCSAP00000000063 PRSS36 PRSS36 FGF8 FGF8 WNT7B WNT7B PDK2 PDK2 KAT7 KAT7 CS CS HSD17B6 HSD17B6 PSMA1 PSMA1 CXCL10 CXCL10 BMPR1B BMPR1B LUM LUM PDE5A PDE5A ST14 ST14 ORAI1 ORAI1 AKT1S1 AKT1S1 HOXB13 HOXB13 MYL2 MYL2 TRPM4 TRPM4 HPGD HPGD PDGFC PDGFC PRSS8 PRSS8 WFDC1 WFDC1 HSD17B2 HSD17B2 INPP4B INPP4B FOLH1 FOLH1 ENSCSAP00000014410 ENSCSAP00000014410 SERPINB5 SERPINB5 RAB27B RAB27B AZGP1 AZGP1 LCP1 LCP1 EDNRB EDNRB IRX4 IRX4 GOLPH3 GOLPH3 PRLR PRLR ZBTB46 ZBTB46 SLC39A2 SLC39A2 TGM4 TGM4 PLPP1 PLPP1 HNMT HNMT TNFRSF10D TNFRSF10D LTF LTF NKX3-1 NKX3-1 PTGDS PTGDS ENSCSAP00000012148 ENSCSAP00000012148 ELOVL7 ELOVL7 ADRA1A ADRA1A DPP4 DPP4 ACTG2 ACTG2 GCNT7 GCNT7 BMX BMX SLC45A3 SLC45A3 RABIF RABIF CGAS CGAS SULF1 SULF1 AKR1C3 AKR1C3 ESR2 ESR2 ABCB5 ABCB5 CALML4 CALML4 ZBTB10 ZBTB10 ARG2 ARG2 RDH11 RDH11 PHF19 PHF19 CTNNA1 CTNNA1 ADRA1D ADRA1D RBM25 RBM25 RNF14 RNF14 ENSCSAP00000008246 ENSCSAP00000008246 TGFB3 TGFB3 AR AR CUL2 CUL2 TGFBR1 TGFBR1 RET RET TES TES GLIPR2 GLIPR2 ACPP ACPP SPDEF SPDEF NR2C2 NR2C2 TP63 TP63 VCL VCL PTN PTN RLN2 RLN2 TMPRSS2 TMPRSS2 PIK3C2G PIK3C2G CST6 CST6 GNAQ GNAQ SIRT1 SIRT1 GCNT2 GCNT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TFAP2ATranscription factor AP-2 alpha. (318 aa)
CTSLCathepsin L; Belongs to the peptidase C1 family. (333 aa)
PIPProlactin induced protein. (146 aa)
TRPM8Transient receptor potential cation channel subfamily M member 8. (1104 aa)
KLK2Kallikrein related peptidase 2; Belongs to the peptidase S1 family. (261 aa)
KLK7Kallikrein related peptidase 7; Belongs to the peptidase S1 family. (252 aa)
KLK11Kallikrein related peptidase 11; Belongs to the peptidase S1 family. (282 aa)
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (470 aa)
S100A4Protein S100; Belongs to the S-100 family. (101 aa)
IL11Interleukin 11. (199 aa)
VTCN1V-set domain containing T cell activation inhibitor 1. (241 aa)
F3Coagulation factor III, tissue factor. (245 aa)
PLA2G2APhospholipase A(2). (144 aa)
SDF4Stromal cell derived factor 4. (362 aa)
PIN4Peptidyl-prolyl cis-trans isomerase. (140 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
TLR2Toll-like receptor. (784 aa)
RNASE1Ribonuclease A family member 1, pancreatic; Belongs to the pancreatic ribonuclease family. (152 aa)
ENSCSAP00000017662Peptidyl-prolyl cis-trans isomerase. (131 aa)
TLR5Toll like receptor 5; Belongs to the Toll-like receptor family. (858 aa)
LOC103230436Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (216 aa)
LIG4DNA ligase. (911 aa)
HDGFL1HDGF like 1. (257 aa)
OR51E2Olfactory receptor. (320 aa)
ANXA2Annexin. (339 aa)
ADRB2Adrenoceptor beta 2. (415 aa)
ENSCSAP00000000063Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
PRSS36Polyserase-2; Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1. Belongs to the peptidase S1 family. (854 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (611 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
HSD17B6Hydroxysteroid 17-beta dehydrogenase 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa)
PSMA1Proteasome subunit alpha type. (130 aa)
CXCL10C-X-C motif chemokine. (98 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
LUMLumican. (338 aa)
PDE5APhosphodiesterase. (875 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
ORAI1ORAI calcium release-activated calcium modulator 1. (303 aa)
AKT1S1AKT1 substrate 1. (256 aa)
HOXB13Homeobox B13. (284 aa)
MYL2Myosin light chain 2. (166 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1214 aa)
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
PDGFCPlatelet derived growth factor C; Belongs to the PDGF/VEGF growth factor family. (345 aa)
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (343 aa)
WFDC1WAP four-disulfide core domain 1. (220 aa)
HSD17B2Hydroxysteroid 17-beta dehydrogenase 2; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (387 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (881 aa)
FOLH1Folate hydrolase 1. (715 aa)
ENSCSAP00000014410ANK_REP_REGION domain-containing protein. (583 aa)
SERPINB5Serpin family B member 5; Belongs to the serpin family. (375 aa)
RAB27BRAB27B, member RAS oncogene family. (218 aa)
AZGP1Alpha-2-glycoprotein 1, zinc-binding; Belongs to the MHC class I family. (298 aa)
LCP1Lymphocyte cytosolic protein 1. (627 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (442 aa)
IRX4Iroquois homeobox 4. (515 aa)
GOLPH3Golgi phosphoprotein 3. (298 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (619 aa)
ZBTB46Zinc finger and BTB domain containing 46. (589 aa)
SLC39A2Solute carrier family 39 member 2. (309 aa)
TGM4Transglutaminase 4. (684 aa)
PLPP1Phospholipid phosphatase 1. (284 aa)
HNMTHistamine N-methyltransferase. (321 aa)
TNFRSF10DTNF receptor superfamily member 10d. (334 aa)
LTFLactotransferrin; Belongs to the transferrin family. (747 aa)
NKX3-1NK3 homeobox 1. (232 aa)
PTGDSLipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
ENSCSAP00000012148ANK_REP_REGION domain-containing protein. (397 aa)
ELOVL7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa)
ADRA1AAdrenoceptor alpha 1A. (425 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (766 aa)
ACTG2Actin gamma 2, smooth muscle. (376 aa)
GCNT7Glucosaminyl (N-acetyl) transferase family member 7. (409 aa)
BMXTyrosine-protein kinase. (677 aa)
SLC45A3Solute carrier family 45 member 3. (553 aa)
RABIFRAB interacting factor. (179 aa)
CGASCyclic GMP-AMP synthase. (526 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (326 aa)
ESR2Estrogen receptor 2. (530 aa)
ABCB5ATP binding cassette subfamily B member 5. (1257 aa)
CALML4Calmodulin like 4. (194 aa)
ZBTB10Zinc finger and BTB domain containing 10. (873 aa)
ARG2Arginase. (354 aa)
RDH11Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
PHF19PHD finger protein 19. (580 aa)
CTNNA1Catenin alpha 1. (906 aa)
ADRA1DAdrenoceptor alpha 1D. (570 aa)
RBM25RNA binding motif protein 25. (843 aa)
RNF14RBR-type E3 ubiquitin transferase. (474 aa)
ENSCSAP00000008246Annexin. (284 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ARAndrogen receptor. (900 aa)
CUL2Cullin 2; Belongs to the cullin family. (842 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1099 aa)
TESTestin LIM domain protein. (421 aa)
GLIPR2GLI pathogenesis related 2; Belongs to the CRISP family. (154 aa)
ACPPAcid phosphatase, prostate; Belongs to the histidine acid phosphatase family. (418 aa)
SPDEFSAM pointed domain containing ETS transcription factor. (335 aa)
NR2C2Nuclear receptor subfamily 2 group C member 2. (629 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (500 aa)
VCLVinculin. (1134 aa)
PTNPleiotrophin. (168 aa)
RLN2Relaxin 2. (185 aa)
TMPRSS2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (492 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1506 aa)
CST6Cystatin E/M; Belongs to the cystatin family. (157 aa)
GNAQG protein subunit alpha q. (301 aa)
SIRT1Sirtuin 1. (743 aa)
GCNT2Glucosaminyl (N-acetyl) transferase 2 (I blood group). (402 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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