node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EME1 | ENSCSAP00000017472 | ENSCSAP00000001707 | ENSCSAP00000017472 | Essential meiotic structure-specific endonuclease 1. | ERCC4 domain-containing protein. | 0.995 |
EME1 | ERCC4 | ENSCSAP00000001707 | ENSCSAP00000004416 | Essential meiotic structure-specific endonuclease 1. | ERCC excision repair 4, endonuclease catalytic subunit. | 0.864 |
EME1 | SLX1 | ENSCSAP00000001707 | ENSCSAP00000002500 | Essential meiotic structure-specific endonuclease 1. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.939 |
EME1 | SLX4 | ENSCSAP00000001707 | ENSCSAP00000006179 | Essential meiotic structure-specific endonuclease 1. | Uncharacterized protein. | 0.954 |
ENSCSAP00000017472 | EME1 | ENSCSAP00000017472 | ENSCSAP00000001707 | ERCC4 domain-containing protein. | Essential meiotic structure-specific endonuclease 1. | 0.995 |
ENSCSAP00000017472 | ERCC4 | ENSCSAP00000017472 | ENSCSAP00000004416 | ERCC4 domain-containing protein. | ERCC excision repair 4, endonuclease catalytic subunit. | 0.937 |
ENSCSAP00000017472 | SLX1 | ENSCSAP00000017472 | ENSCSAP00000002500 | ERCC4 domain-containing protein. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.848 |
ENSCSAP00000017472 | SLX4 | ENSCSAP00000017472 | ENSCSAP00000006179 | ERCC4 domain-containing protein. | Uncharacterized protein. | 0.989 |
ERCC4 | EME1 | ENSCSAP00000004416 | ENSCSAP00000001707 | ERCC excision repair 4, endonuclease catalytic subunit. | Essential meiotic structure-specific endonuclease 1. | 0.864 |
ERCC4 | ENSCSAP00000017472 | ENSCSAP00000004416 | ENSCSAP00000017472 | ERCC excision repair 4, endonuclease catalytic subunit. | ERCC4 domain-containing protein. | 0.937 |
ERCC4 | SLX1 | ENSCSAP00000004416 | ENSCSAP00000002500 | ERCC excision repair 4, endonuclease catalytic subunit. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.949 |
ERCC4 | SLX4 | ENSCSAP00000004416 | ENSCSAP00000006179 | ERCC excision repair 4, endonuclease catalytic subunit. | Uncharacterized protein. | 0.973 |
SLX1 | EME1 | ENSCSAP00000002500 | ENSCSAP00000001707 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | Essential meiotic structure-specific endonuclease 1. | 0.939 |
SLX1 | ENSCSAP00000017472 | ENSCSAP00000002500 | ENSCSAP00000017472 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | ERCC4 domain-containing protein. | 0.848 |
SLX1 | ERCC4 | ENSCSAP00000002500 | ENSCSAP00000004416 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | ERCC excision repair 4, endonuclease catalytic subunit. | 0.949 |
SLX1 | SLX4 | ENSCSAP00000002500 | ENSCSAP00000006179 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | Uncharacterized protein. | 0.994 |
SLX4 | EME1 | ENSCSAP00000006179 | ENSCSAP00000001707 | Uncharacterized protein. | Essential meiotic structure-specific endonuclease 1. | 0.954 |
SLX4 | ENSCSAP00000017472 | ENSCSAP00000006179 | ENSCSAP00000017472 | Uncharacterized protein. | ERCC4 domain-containing protein. | 0.989 |
SLX4 | ERCC4 | ENSCSAP00000006179 | ENSCSAP00000004416 | Uncharacterized protein. | ERCC excision repair 4, endonuclease catalytic subunit. | 0.973 |
SLX4 | SLX1 | ENSCSAP00000006179 | ENSCSAP00000002500 | Uncharacterized protein. | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. | 0.994 |