(14 nodes) Prp19 complex, and U2-type catalytic step 2 spliceosome network (Chlorocebus sabaeus)

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Your Input:
	PRPF19	Pre-mRNA processing factor 19. (504 aa)
	AQR	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing. (1492 aa)
	XAB2	XPA binding protein 2. (855 aa)
	ISY1	Uncharacterized protein. (285 aa)
	CRNKL1	Crooked neck pre-mRNA splicing factor 1. (687 aa)
	SNW1	SNW domain containing 1. (536 aa)
	CDC5L	Cell division cycle 5 like. (802 aa)
	CTNNBL1	DUF1716 domain-containing protein. (563 aa)
	BUD31	BUD31 homolog. (144 aa)
	CWC15	CWC15 spliceosome associated protein homolog. (229 aa)
	PLRG1	Pleiotropic regulator 1. (514 aa)
	BCAS2	BCAS2 pre-mRNA processing factor. (225 aa)
	PPIE	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (304 aa)
	RBM22	Uncharacterized protein. (394 aa)

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AQR	BCAS2	ENSCSAP00000003428	ENSCSAP00000016375	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	BCAS2 pre-mRNA processing factor.	0.966
AQR	BUD31	ENSCSAP00000003428	ENSCSAP00000013816	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	BUD31 homolog.	0.990
AQR	CDC5L	ENSCSAP00000003428	ENSCSAP00000008644	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Cell division cycle 5 like.	0.983
AQR	CRNKL1	ENSCSAP00000003428	ENSCSAP00000007636	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Crooked neck pre-mRNA splicing factor 1.	0.995
AQR	CTNNBL1	ENSCSAP00000003428	ENSCSAP00000009871	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	DUF1716 domain-containing protein.	0.503
AQR	CWC15	ENSCSAP00000003428	ENSCSAP00000014749	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	CWC15 spliceosome associated protein homolog.	0.934
AQR	ISY1	ENSCSAP00000003428	ENSCSAP00000005028	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Uncharacterized protein.	0.969
AQR	PLRG1	ENSCSAP00000003428	ENSCSAP00000014772	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Pleiotropic regulator 1.	0.962
AQR	PPIE	ENSCSAP00000003428	ENSCSAP00000016883	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.	0.985
AQR	PRPF19	ENSCSAP00000003428	ENSCSAP00000002546	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Pre-mRNA processing factor 19.	0.996
AQR	RBM22	ENSCSAP00000003428	ENSCSAP00000018521	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	Uncharacterized protein.	0.987
AQR	SNW1	ENSCSAP00000003428	ENSCSAP00000007929	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	SNW domain containing 1.	0.989
AQR	XAB2	ENSCSAP00000003428	ENSCSAP00000004614	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	XPA binding protein 2.	0.997
BCAS2	AQR	ENSCSAP00000016375	ENSCSAP00000003428	BCAS2 pre-mRNA processing factor.	RNA helicase aquarius; Intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. Plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. May act by helping the folding of the snoRNA sequence. Binds to intron of pre- mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.	0.966
BCAS2	BUD31	ENSCSAP00000016375	ENSCSAP00000013816	BCAS2 pre-mRNA processing factor.	BUD31 homolog.	0.950
BCAS2	CDC5L	ENSCSAP00000016375	ENSCSAP00000008644	BCAS2 pre-mRNA processing factor.	Cell division cycle 5 like.	0.997
BCAS2	CRNKL1	ENSCSAP00000016375	ENSCSAP00000007636	BCAS2 pre-mRNA processing factor.	Crooked neck pre-mRNA splicing factor 1.	0.944
BCAS2	CTNNBL1	ENSCSAP00000016375	ENSCSAP00000009871	BCAS2 pre-mRNA processing factor.	DUF1716 domain-containing protein.	0.967
BCAS2	CWC15	ENSCSAP00000016375	ENSCSAP00000014749	BCAS2 pre-mRNA processing factor.	CWC15 spliceosome associated protein homolog.	0.993
BCAS2	ISY1	ENSCSAP00000016375	ENSCSAP00000005028	BCAS2 pre-mRNA processing factor.	Uncharacterized protein.	0.843

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