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LDHD LDHD PGM2L1 PGM2L1 GAPDHS GAPDHS GPI GPI GOT2 GOT2 ENO4 ENO4 GALK1 GALK1 ENSCSAP00000001333 ENSCSAP00000001333 LDHAL6A LDHAL6A LDHC LDHC CS CS PDK2 PDK2 PDHX PDHX MYCBPAP MYCBPAP ACCS ACCS GPT2 GPT2 PGLS PGLS GOT1 GOT1 ACO2 ACO2 GBE1 GBE1 NIT2 NIT2 ALDOA ALDOA PFKM PFKM ENSCSAP00000002674 ENSCSAP00000002674 FBP2 FBP2 FBP1 FBP1 ENSCSAP00000002931 ENSCSAP00000002931 G6PD G6PD TKTL1 TKTL1 IDH3G IDH3G ALDOC ALDOC PYGM PYGM IDNK IDNK MPST MPST TST TST PFKL PFKL HKDC1 HKDC1 BCAT1 BCAT1 HK1 HK1 LDHB LDHB GYS2 GYS2 PRPSAP2 PRPSAP2 GFPT2 GFPT2 GPT GPT DERA DERA PC PC PGM5 PGM5 PRPS1 PRPS1 HK3 HK3 ENSCSAP00000005443 ENSCSAP00000005443 BPGM BPGM FH FH ACO1 ACO1 RPE RPE IDH1 IDH1 GCKR GCKR GALT GALT ENO2 ENO2 TPI1 TPI1 RBKS RBKS OGDHL OGDHL AMDHD2 AMDHD2 GAPDH GAPDH URB2 URB2 GALK2 GALK2 TALDO1 TALDO1 GNE GNE PGK1 PGK1 IDH3B IDH3B PGGHG PGGHG TIGAR TIGAR ALDOB ALDOB DLD DLD GYG1 GYG1 SUCLG2 SUCLG2 YIPF6 YIPF6 ENSCSAP00000008052 ENSCSAP00000008052 PFKFB1 PFKFB1 PDHB PDHB ENSCSAP00000008427 ENSCSAP00000008427 GALM GALM DLST DLST ENSCSAP00000008535 ENSCSAP00000008535 GNPDA1 GNPDA1 ENSCSAP00000008632 ENSCSAP00000008632 ENO3 ENO3 TKT TKT DHTKD1 DHTKD1 PFKFB3 PFKFB3 ENSCSAP00000009699 ENSCSAP00000009699 ENSCSAP00000009906 ENSCSAP00000009906 PARP6 PARP6 RGN RGN GLYCTK GLYCTK ADPGK ADPGK PFKP PFKP RBM45 RBM45 PDK3 PDK3 MDH1 MDH1 UGP2 UGP2 PDK1 PDK1 IDH3A IDH3A GNPNAT1 GNPNAT1 PFKFB2 PFKFB2 PYGL PYGL NAGK NAGK PUDP PUDP DDO DDO PGAM2 PGAM2 GOT1L1 GOT1L1 PCK1 PCK1 GCK GCK OGDH OGDH GYG2 GYG2 HK2 HK2 SUCLG1 SUCLG1 ENSCSAP00000012133 ENSCSAP00000012133 LDHA LDHA PCK2 PCK2 SDHC SDHC RPIA RPIA UAP1L1 UAP1L1 PARP8 PARP8 PGM2 PGM2 UGDH UGDH UXS1 UXS1 IDH2 IDH2 GNPDA2 GNPDA2 ME1 ME1 PGM3 PGM3 BCKDHB BCKDHB TGDS TGDS SUCLA2 SUCLA2 RNF138 RNF138 ME2 ME2 MDH2 MDH2 PYGB PYGB ME3 ME3 BCKDHA BCKDHA G6PC3 G6PC3 ENSCSAP00000014573 ENSCSAP00000014573 G6PC G6PC DLAT DLAT SDHD SDHD BCAT2 BCAT2 GYS1 GYS1 UAP1 UAP1 TREH TREH IL4I1 IL4I1 PKLR PKLR ENSCSAP00000016507 ENSCSAP00000016507 DBT DBT AGL AGL PGM1 PGM1 GALE GALE SDHB SDHB PGD PGD H6PD H6PD ENO1 ENO1 PDHA2 PDHA2 LOC103230363 LOC103230363 ENSCSAP00000018170 ENSCSAP00000018170 ENSCSAP00000018380 ENSCSAP00000018380 PGK2 PGK2 PNMA8B PNMA8B LDHAL6B LDHAL6B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LDHDLactate dehydrogenase D. (484 aa)
PGM2L1Phosphoglucomutase 2 like 1. (622 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (409 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (600 aa)
GOT2Aspartate aminotransferase. (430 aa)
ENO4Enolase 4. (633 aa)
GALK1Galactokinase 1. (338 aa)
ENSCSAP00000001333L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (356 aa)
LDHAL6AL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
LDHCL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (216 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (466 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (501 aa)
MYCBPAPMYCBP associated protein. (937 aa)
ACCS1-aminocyclopropane-1-carboxylate synthase homolog (inactive). (501 aa)
GPT2Glutamic--pyruvic transaminase 2. (523 aa)
PGLS6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (317 aa)
GOT1Aspartate aminotransferase. (413 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa)
GBE11,4-alpha-glucan branching enzyme 1. (702 aa)
NIT2Nitrilase family member 2. (278 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
PFKMATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (851 aa)
ENSCSAP00000002674Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (319 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (339 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
ENSCSAP00000002931Phosphoglycerate kinase. (342 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa)
TKTL1Transketolase like 1. (596 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (404 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
PYGMAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (804 aa)
IDNKGluconokinase; Belongs to the gluconokinase GntK/GntV family. (187 aa)
MPSTSulfurtransferase. (317 aa)
TSTSulfurtransferase. (297 aa)
PFKLATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
HKDC1Hexokinase domain containing 1. (917 aa)
BCAT1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (391 aa)
HK1Hexokinase 1. (917 aa)
LDHBL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (334 aa)
GYS2Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (703 aa)
PRPSAP2Pribosyltran_N domain-containing protein. (161 aa)
GFPT2Glutamine-fructose-6-phosphate transaminase 2. (682 aa)
GPTGlutamic--pyruvic transaminase. (496 aa)
DERADeoxyribose-phosphate aldolase. (318 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1179 aa)
PGM5Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
PRPS1Uncharacterized protein. (204 aa)
HK3Hexokinase 3. (923 aa)
ENSCSAP00000005443Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (319 aa)
BPGMPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (259 aa)
FHFumarate hydratase. (510 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (895 aa)
RPERibulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
GCKRGlucokinase regulator. (625 aa)
GALTGalactose-1-phosphate uridylyltransferase. (379 aa)
ENO2Enolase 2. (434 aa)
TPI1Triosephosphate isomerase. (286 aa)
RBKSRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (267 aa)
OGDHLOxoglutarate dehydrogenase like. (1037 aa)
AMDHD2N-acetylglucosamine-6-phosphate deacetylase; Hydrolyzes the N-glycolyl group from N-glycolylglucosamine 6- phosphate (GlcNGc-6-P) in the N-glycolylneuraminic acid (Neu5Gc) degradation pathway. (409 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (335 aa)
URB2URB2 ribosome biogenesis homolog. (1524 aa)
GALK2Galactokinase 2. (458 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa)
GNEGlucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase. (753 aa)
PGK1Phosphoglycerate kinase. (382 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa)
PGGHGProtein-glucosylgalactosylhydroxylysine glucosidase. (727 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
DLDDihydrolipoyl dehydrogenase. (538 aa)
GYG1Glycogenin 1. (350 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (432 aa)
YIPF6Protein YIPF. (236 aa)
ENSCSAP00000008052Phosphoglycerate kinase. (403 aa)
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (479 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (359 aa)
ENSCSAP00000008427Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (330 aa)
GALMAldose 1-epimerase; Converts alpha-aldose to the beta-anomer. (342 aa)
DLSTDihydrolipoamide S-succinyltransferase. (454 aa)
ENSCSAP00000008535Glyceraldehyde-3-phosphate dehydrogenase. (292 aa)
GNPDA1Glucosamine-6-phosphate isomerase. (289 aa)
ENSCSAP00000008632Uncharacterized protein; Belongs to the LDH/MDH superfamily. (329 aa)
ENO3Enolase 3. (434 aa)
TKTTransketolase. (623 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (921 aa)
PFKFB36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (475 aa)
ENSCSAP00000009699Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (321 aa)
ENSCSAP00000009906Pyruvate kinase; Belongs to the pyruvate kinase family. (333 aa)
PARP6Poly [ADP-ribose] polymerase. (610 aa)
RGNRegucalcin. (299 aa)
GLYCTKGlycerate kinase. (523 aa)
ADPGKADP dependent glucokinase. (497 aa)
PFKPATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (807 aa)
RBM45RNA binding motif protein 45. (474 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
MDH1Malate dehydrogenase. (334 aa)
UGP2UTP--glucose-1-phosphate uridylyltransferase. (508 aa)
PDK1Protein-serine/threonine kinase. (436 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
GNPNAT1Glucosamine 6-phosphate N-acetyltransferase. (184 aa)
PFKFB26-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (505 aa)
PYGLAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (847 aa)
NAGKN-acetylglucosamine kinase. (344 aa)
PUDPPseudouridine 5'-phosphatase. (229 aa)
DDOD-aspartate oxidase. (292 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (420 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
GCKPhosphotransferase. (466 aa)
OGDHOxoglutarate dehydrogenase. (1038 aa)
GYG2Glycogenin 2. (470 aa)
HK2Hexokinase 2. (917 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (395 aa)
ENSCSAP00000012133Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (601 aa)
LDHAL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (343 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
SDHCUncharacterized protein. (150 aa)
RPIARibose 5-phosphate isomerase A. (311 aa)
UAP1L1UDP-N-acetylglucosamine pyrophosphorylase 1 like 1. (382 aa)
PARP8Poly [ADP-ribose] polymerase. (893 aa)
PGM2Phosphoglucomutase 2. (612 aa)
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
UXS1UDP-glucuronate decarboxylase 1. (420 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa)
GNPDA2Glucosamine-6-phosphate isomerase. (276 aa)
ME1Malic enzyme. (572 aa)
PGM3Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family. (542 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (392 aa)
TGDSTDP-glucose 4,6-dehydratase. (350 aa)
SUCLA2Succinate-CoA ligase ADP-forming beta subunit. (274 aa)
RNF138Ring finger protein 138. (245 aa)
ME2Malic enzyme. (584 aa)
MDH2Malate dehydrogenase 2. (416 aa)
PYGBAlpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (695 aa)
ME3Malic enzyme. (604 aa)
BCKDHA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (445 aa)
G6PC3Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (346 aa)
ENSCSAP00000014573Uncharacterized protein. (247 aa)
G6PCGlucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (647 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (140 aa)
BCAT2Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (352 aa)
GYS1Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (737 aa)
UAP1UDP-N-acetylglucosamine pyrophosphorylase 1. (522 aa)
TREHTrehalase. (565 aa)
IL4I1Amine oxidase. (588 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (481 aa)
ENSCSAP00000016507Alpha-amylase; Belongs to the glycosyl hydrolase 13 family. (492 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (482 aa)
AGLAmylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase. (1532 aa)
PGM1Phosphoglucomutase 1; Belongs to the phosphohexose mutase family. (580 aa)
GALEUDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (280 aa)
PGDPhosphogluconate dehydrogenase. (311 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (802 aa)
ENO1Enolase 1. (434 aa)
PDHA2Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (388 aa)
LOC103230363Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
ENSCSAP00000018170Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
ENSCSAP00000018380Uncharacterized protein. (254 aa)
PGK2Phosphoglycerate kinase. (417 aa)
PNMA8BPNMA family member 8B. (634 aa)
LDHAL6BL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (381 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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