STRINGSTRING
ATG13 ATG13 UBQLN2 UBQLN2 EMC6 EMC6 MFN2 MFN2 RAB7A RAB7A UBXN2A UBXN2A RAB19 RAB19 ATG9A ATG9A RAB1B RAB1B ULK2 ULK2 ATG2A ATG2A ATG4D ATG4D ATG9B ATG9B ATG3 ATG3 ATG16L1 ATG16L1 ENSCSAP00000005633 ENSCSAP00000005633 PACS2 PACS2 VMP1 VMP1 ATG101 ATG101 ATG4B ATG4B BECN2 BECN2 AMBRA1 AMBRA1 BAG3 BAG3 STBD1 STBD1 TMEM41B TMEM41B ARFIP2 ARFIP2 WIPI1 WIPI1 ATG16L2 ATG16L2 SYNPO2 SYNPO2 GABARAPL2 GABARAPL2 ATG7 ATG7 RUFY4 RUFY4 TCIRG1 TCIRG1 RAB43 RAB43 ATG2B ATG2B NSFL1C NSFL1C STX17 STX17 TP53INP2 TP53INP2 MAP1LC3C MAP1LC3C MAP1LC3A MAP1LC3A TP53INP1 TP53INP1 PSEN1 PSEN1 WDR45 WDR45 STING1 STING1 RAB23 RAB23 UBXN2B UBXN2B ATG14 ATG14 RB1CC1 RB1CC1 ATG5 ATG5 RAB1A RAB1A ATG12 ATG12 EPM2A EPM2A WIPI2 WIPI2 SMURF1 SMURF1 AP4M1 AP4M1 TRAPPC8 TRAPPC8 PIK3C3 PIK3C3 RAB33B RAB33B LRBA LRBA BECN1 BECN1 MAP1LC3B MAP1LC3B ATP2A2 ATP2A2 WDR45B WDR45B ULK1 ULK1 KIAA1324 KIAA1324 STX12 STX12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
UBQLN2Ubiquilin 2. (624 aa)
EMC6ER membrane protein complex subunit 6. (110 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
UBXN2AUBX domain protein 2A. (260 aa)
RAB19RAB19, member RAS oncogene family. (217 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
RAB1BRAB1B, member RAS oncogene family. (224 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1036 aa)
ATG2AAutophagy related 2A. (1932 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (474 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
ATG3Autophagy-related protein 3. (314 aa)
ATG16L1Autophagy related 16 like 1. (588 aa)
ENSCSAP00000005633Uncharacterized protein. (148 aa)
PACS2Phosphofurin acidic cluster sorting protein 2. (879 aa)
VMP1Vacuole membrane protein 1. (406 aa)
ATG101Autophagy related 101. (218 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa)
BECN2Beclin 2. (440 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1208 aa)
BAG3BCL2 associated athanogene 3. (575 aa)
STBD1Starch binding domain 1. (358 aa)
TMEM41BTransmembrane protein 41B. (291 aa)
ARFIP2ADP ribosylation factor interacting protein 2. (341 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (446 aa)
ATG16L2Autophagy related 16 like 2. (621 aa)
SYNPO2Synaptopodin 2. (1245 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (703 aa)
RUFY4RUN and FYVE domain containing 4. (571 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
RAB43RAB43, member RAS oncogene family. (212 aa)
ATG2BAutophagy related 2B. (2078 aa)
NSFL1CNSFL1 cofactor. (370 aa)
STX17Syntaxin 17; Belongs to the syntaxin family. (302 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (220 aa)
MAP1LC3CMicrotubule associated protein 1 light chain 3 gamma. (147 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (121 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (165 aa)
PSEN1Presenilin 1. (467 aa)
WDR45Uncharacterized protein. (360 aa)
STING1Transmembrane protein 173. (379 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
UBXN2BUBX domain protein 2B. (331 aa)
ATG14Autophagy related 14. (492 aa)
RB1CC1RB1 inducible coiled-coil 1. (1594 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
RAB1AUncharacterized protein. (144 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (443 aa)
SMURF1E3 ubiquitin-protein ligase. (728 aa)
AP4M1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (453 aa)
TRAPPC8Trafficking protein particle complex 8. (1435 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
LRBALPS responsive beige-like anchor protein. (2113 aa)
BECN1Beclin 1. (450 aa)
MAP1LC3BUncharacterized protein. (125 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (997 aa)
WDR45BWD repeat domain 45B. (344 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1070 aa)
KIAA1324KIAA1324. (987 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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