46 items (Chlorocebus sabaeus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PER2	Period circadian regulator 2. (1254 aa)
	EED	Embryonic ectoderm development. (441 aa)
	LEF1	Lymphoid enhancer binding factor 1. (331 aa)
	CNOT2	CCR4-NOT transcription complex subunit 2. (540 aa)
	CTBP2	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (386 aa)
	ENSCSAP00000002340	HTH psq-type domain-containing protein. (575 aa)
	WIZ	WIZ zinc finger. (649 aa)
	SUZ12	SUZ12 polycomb repressive complex 2 subunit. (739 aa)
	EZH2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
	PHF12	PHD finger protein 12. (1004 aa)
	FAM89B	Family with sequence similarity 89 member B. (189 aa)
	STK36	Serine/threonine kinase 36. (1317 aa)
	RUNX1	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (456 aa)
	EHMT2	Euchromatic histone lysine methyltransferase 2. (1197 aa)
	BCL6	BCL6 transcription repressor. (708 aa)
	PHF1	PHD finger protein 1. (567 aa)
	ELOB	Ubiquitin-like domain-containing protein. (118 aa)
	PBX1	PBX homeobox 1. (301 aa)
	PER1	Period circadian regulator 1. (1292 aa)
	ZBTB7A	Zinc finger and BTB domain containing 7A. (584 aa)
	RORA	RAR related orphan receptor A. (490 aa)
	STAT1	Signal transducer and activator of transcription. (750 aa)
	HDAC3	Hist_deacetyl domain-containing protein. (266 aa)
	THAP7	THAP domain containing 7. (309 aa)
	HDAC6	Histone deacetylase 6. (1215 aa)
	SIX3	SIX homeobox 3. (331 aa)
	ELOC	Elongin C; Belongs to the SKP1 family. (112 aa)
	NEK6	NIMA related kinase 6; Belongs to the protein kinase superfamily. (313 aa)
	USP11	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (963 aa)
	ESR1	Estrogen receptor 1. (487 aa)
	CTBP1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (421 aa)
	EHMT1	Euchromatic histone lysine methyltransferase 1. (1267 aa)
	NR1D1	Nuclear receptor subfamily 1 group D member 1. (613 aa)
	ZBTB16	Zinc finger and BTB domain containing 16. (673 aa)
	ETS1	ETS proto-oncogene 1, transcription factor. (441 aa)
	HDGF	Heparin binding growth factor. (225 aa)
	ENSCSAP00000016053	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (497 aa)
	MTF2	Metal response element binding transcription factor 2. (593 aa)
	ZNF644	Zinc finger protein 644. (1327 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	RUNX3	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (428 aa)
	PER3	Period circadian regulator 3. (1182 aa)
	TP73	Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (637 aa)
	ENSCSAP00000017424	Ubiquitin-like domain-containing protein. (118 aa)
	ENSCSAP00000017750	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (479 aa)
	ENSCSAP00000018734	Ubiquitin-like domain-containing protein. (118 aa)

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL6	ENSCSAP00000016053	ENSCSAP00000005366	ENSCSAP00000016053	BCL6 transcription repressor.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.469
BCL6	ENSCSAP00000017750	ENSCSAP00000005366	ENSCSAP00000017750	BCL6 transcription repressor.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.469
BCL6	EZH2	ENSCSAP00000005366	ENSCSAP00000003315	BCL6 transcription repressor.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.407
BCL6	HDAC1	ENSCSAP00000005366	ENSCSAP00000016960	BCL6 transcription repressor.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.469
BCL6	LEF1	ENSCSAP00000005366	ENSCSAP00000000331	BCL6 transcription repressor.	Lymphoid enhancer binding factor 1.	0.445
BCL6	STAT1	ENSCSAP00000005366	ENSCSAP00000008380	BCL6 transcription repressor.	Signal transducer and activator of transcription.	0.479
CNOT2	ZNF644	ENSCSAP00000000534	ENSCSAP00000016566	CCR4-NOT transcription complex subunit 2.	Zinc finger protein 644.	0.633
CTBP1	CTBP2	ENSCSAP00000011669	ENSCSAP00000000840	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.900
CTBP1	EHMT1	ENSCSAP00000011669	ENSCSAP00000012911	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Euchromatic histone lysine methyltransferase 1.	0.428
CTBP1	EHMT2	ENSCSAP00000011669	ENSCSAP00000005100	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Euchromatic histone lysine methyltransferase 2.	0.473
CTBP1	ENSCSAP00000016053	ENSCSAP00000011669	ENSCSAP00000016053	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.939
CTBP1	ENSCSAP00000017750	ENSCSAP00000011669	ENSCSAP00000017750	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.710
CTBP1	HDAC1	ENSCSAP00000011669	ENSCSAP00000016960	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.951
CTBP1	HDAC3	ENSCSAP00000011669	ENSCSAP00000008654	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Hist_deacetyl domain-containing protein.	0.480
CTBP1	LEF1	ENSCSAP00000011669	ENSCSAP00000000331	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lymphoid enhancer binding factor 1.	0.956
CTBP1	RUNX1	ENSCSAP00000011669	ENSCSAP00000004965	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.928
CTBP1	WIZ	ENSCSAP00000011669	ENSCSAP00000002381	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	WIZ zinc finger.	0.527
CTBP2	CTBP1	ENSCSAP00000000840	ENSCSAP00000011669	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.900
CTBP2	ENSCSAP00000016053	ENSCSAP00000000840	ENSCSAP00000016053	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.893
CTBP2	ENSCSAP00000017750	ENSCSAP00000000840	ENSCSAP00000017750	Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.491

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