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KCNJ5 KCNJ5 P2RX7 P2RX7 P2RX4 P2RX4 MYH14 MYH14 KCND3 KCND3 CLDN19 CLDN19 MTOR MTOR KCNE3 KCNE3 KCNJ2 KCNJ2 KCNE5 KCNE5 KCNA2 KCNA2 GPR88 GPR88 KCNE2 KCNE2 KCNE1 KCNE1 KCNE4 KCNE4 KCNA1 KCNA1 KCNA5 KCNA5 GPER1 GPER1 ANK2 ANK2 KCNH6 KCNH6 SCN4A SCN4A KCNC2 KCNC2 SCN1B SCN1B CACNA1G CACNA1G KCNIP2 KCNIP2 SCN8A SCN8A P2RX3 P2RX3 CACNA1I CACNA1I KCNH2 KCNH2 GJD2 GJD2 CLCN1 CLCN1 PKP2 PKP2 CNTNAP1 CNTNAP1 NUP155 NUP155 AKAP7 AKAP7 GJA1 GJA1 CACNB4 CACNB4 KCNJ3 KCNJ3 AKAP6 AKAP6 KCNH7 KCNH7 SCN3A SCN3A SCN2A SCN2A SCN1A SCN1A SCN9A SCN9A SCN7A SCN7A KCNB1 KCNB1 CHRNB4 CHRNB4 KCNN2 KCNN2 GRIK2 GRIK2 SCN11A SCN11A SCN10A SCN10A CHRNA1 CHRNA1 SCN5A SCN5A ENSCSAP00000010271 ENSCSAP00000010271 DMD DMD YWHAE YWHAE HCN4 HCN4 P2RX1 P2RX1 CACNA1D CACNA1D HCN2 HCN2 KCNMB3 KCNMB3 KCNMB2 KCNMB2 CACNB2 CACNB2 SLC8A1 SLC8A1 SNTA1 SNTA1 CACNA2D1 CACNA2D1 CACNA1H CACNA1H CACNA1C CACNA1C GNA11 GNA11 GNA15 GNA15 NRCAM NRCAM GLRA1 GLRA1 CAV3 CAV3 KCND2 KCND2 RYR2 RYR2 KCNQ1 KCNQ1 PMP22 PMP22 ANK3 ANK3 NTRK2 NTRK2 GNAQ GNAQ GNA14 GNA14 SLC4A3 SLC4A3 KCNJ8 KCNJ8 YWHAH YWHAH FKBP1B FKBP1B TRPM4 TRPM4 SCN4B SCN4B SCN2B SCN2B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KCNJ5Potassium voltage-gated channel subfamily J member 5. (432 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (491 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (358 aa)
MYH14Myosin heavy chain 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
KCND3Potassium voltage-gated channel subfamily D member 3; Belongs to the potassium channel family. (655 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (181 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
KCNE3Potassium voltage-gated channel subfamily E regulatory subunit 3. (103 aa)
KCNJ2Potassium voltage-gated channel subfamily J member 2. (427 aa)
KCNE5Potassium voltage-gated channel subfamily E regulatory subunit 5. (142 aa)
KCNA2Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
GPR88G protein-coupled receptor 88. (384 aa)
KCNE2Potassium voltage-gated channel subfamily E regulatory subunit 2. (123 aa)
KCNE1Uncharacterized protein. (146 aa)
KCNE4Potassium voltage-gated channel subfamily E regulatory subunit 4. (170 aa)
KCNA1Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (495 aa)
KCNA5Potassium voltage-gated channel subfamily A member 5; Belongs to the potassium channel family. (605 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
ANK2Ankyrin 2. (4035 aa)
KCNH6Potassium voltage-gated channel subfamily H member 6. (994 aa)
SCN4ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1836 aa)
KCNC2Potassium voltage-gated channel subfamily C member 2; Belongs to the potassium channel family. (638 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (218 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2186 aa)
KCNIP2Potassium voltage-gated channel interacting protein 2. (285 aa)
SCN8ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1980 aa)
P2RX3Purinergic receptor P2X 3. (298 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2234 aa)
KCNH2Potassium voltage-gated channel subfamily H member 2. (1160 aa)
GJD2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (321 aa)
CLCN1Chloride channel protein. (988 aa)
PKP2Plakophilin 2. (837 aa)
CNTNAP1Contactin associated protein 1. (1382 aa)
NUP155Nucleoporin 155. (1080 aa)
AKAP7A-kinase anchoring protein 7. (348 aa)
GJA1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (382 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (486 aa)
KCNJ3Potassium voltage-gated channel subfamily J member 3. (501 aa)
AKAP6A-kinase anchoring protein 6. (2319 aa)
KCNH7Potassium voltage-gated channel subfamily H member 7. (1093 aa)
SCN3ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1701 aa)
SCN2ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2052 aa)
SCN1ASodium voltage-gated channel alpha subunit 1. (1359 aa)
SCN9ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1992 aa)
SCN7ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1680 aa)
KCNB1Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (753 aa)
CHRNB4Cholinergic receptor nicotinic beta 4 subunit. (492 aa)
KCNN2Potassium calcium-activated channel subfamily N member 2. (846 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (859 aa)
SCN11ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1791 aa)
SCN10ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1956 aa)
CHRNA1Neur_chan_LBD domain-containing protein. (248 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1881 aa)
ENSCSAP00000010271ZZ-type domain-containing protein. (595 aa)
DMDUncharacterized protein. (774 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (240 aa)
HCN4Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1203 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2036 aa)
HCN2Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2. (806 aa)
KCNMB3Potassium calcium-activated channel subfamily M regulatory beta subunit 3. (286 aa)
KCNMB2KcnmB2_inactiv domain-containing protein. (235 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (612 aa)
SLC8A1Solute carrier family 8 member A1; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (632 aa)
SNTA1Syntrophin alpha 1. (505 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (962 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2240 aa)
CACNA1CCalcium voltage-gated channel subunit alpha1 C. (1898 aa)
GNA11G protein subunit alpha 11. (394 aa)
GNA15G protein subunit alpha 15. (374 aa)
NRCAMNeuronal cell adhesion molecule. (1298 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (457 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
KCND2Potassium voltage-gated channel subfamily D member 2; Belongs to the potassium channel family. (389 aa)
RYR2Ryanodine receptor 2. (4906 aa)
KCNQ1Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (518 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
ANK3Ankyrin 3. (2797 aa)
NTRK2Neurotrophic receptor tyrosine kinase 2. (477 aa)
GNAQG protein subunit alpha q. (301 aa)
GNA14G protein subunit alpha 14. (355 aa)
SLC4A3Anion exchange protein. (1232 aa)
KCNJ8Potassium voltage-gated channel subfamily J member 8. (424 aa)
YWHAHTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (246 aa)
FKBP1BPeptidylprolyl isomerase. (108 aa)
TRPM4Transient receptor potential cation channel subfamily M member 4. (1214 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (228 aa)
SCN2BSodium voltage-gated channel beta subunit 2. (215 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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