STRINGSTRING
CHD7 CHD7 HOXA3 HOXA3 JAG1 JAG1 CRB1 CRB1 EPAS1 EPAS1 SEMA3C SEMA3C ACVR2B ACVR2B ATG5 ATG5 MEF2C MEF2C DBH DBH RSPO3 RSPO3 FGF10 FGF10 AXL AXL EDNRA EDNRA BAX BAX FOXC2 FOXC2 CCR2 CCR2 FOXC1 FOXC1 AGTR2 AGTR2 NOL3 NOL3 FGF8 FGF8 ACVRL1 ACVRL1 FLNA FLNA NOS3 NOS3 EXT1 EXT1 ATP7A ATP7A BMPR2 BMPR2 BAK1 BAK1 LIF LIF DLL4 DLL4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
HOXA3Homeobox A3. (443 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
CRB1Crumbs cell polarity complex component 1. (1335 aa)
EPAS1Endothelial PAS domain protein 1. (869 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
MEF2CMyocyte enhancer factor 2C. (446 aa)
DBHDopamine beta-hydroxylase. (597 aa)
RSPO3R-spondin 3. (273 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
FOXC2Forkhead box C2. (501 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
FOXC1Forkhead box C1. (552 aa)
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
NOL3Nucleolar protein 3. (265 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
FLNAFilamin A. (2639 aa)
NOS3Nitric oxide synthase 3. (867 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (420 aa)
ATP7AATPase copper transporting alpha. (1500 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
BAK1BCL2 antagonist/killer 1. (211 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (22%) [HD]