STRINGSTRING
TBX20 TBX20 BMP4 BMP4 ISL1 ISL1 GATA6 GATA6 ZFPM2 ZFPM2 SEMA3C SEMA3C SMAD6 SMAD6 ENG ENG SMAD4 SMAD4 BMPR1A BMPR1A NRP2 NRP2 BMPR2 BMPR2 NRP1 NRP1 TBX1 TBX1 TGFBR2 TGFBR2 NKX2-5 NKX2-5 TBX2 TBX2 ROBO1 ROBO1 ROBO2 ROBO2 ENSCSAP00000002167 ENSCSAP00000002167 FGF8 FGF8 FGFR2 FGFR2 PARVA PARVA TGFB2 TGFB2 LRP2 LRP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBX20T-box transcription factor 20. (447 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
ISL1ISL LIM homeobox 1. (349 aa)
GATA6GATA binding protein 6. (595 aa)
ZFPM2Zinc finger protein, FOG family member 2. (940 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
ENGEndoglin. (658 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (901 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
TBX1T-box transcription factor 1. (490 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
NKX2-5NK2 homeobox 5. (324 aa)
TBX2T-box transcription factor 2. (588 aa)
ROBO1Uncharacterized protein. (1466 aa)
ROBO2Roundabout guidance receptor 2. (1235 aa)
ENSCSAP00000002167Ig-like domain-containing protein. (131 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
PARVAParvin alpha. (372 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
LRP2LDL receptor related protein 2. (3861 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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