STRINGSTRING
BMPR1A BMPR1A SLIT3 SLIT3 BMPR2 BMPR2 ADAMTS9 ADAMTS9 SMAD6 SMAD6 HEY1 HEY1 GATA3 GATA3 BMP2 BMP2 JAG1 JAG1 STRA6 STRA6 MDM4 MDM4 MEF2C MEF2C SNAI2 SNAI2 BMP4 BMP4 TBX20 TBX20 SNAI1 SNAI1 FGFRL1 FGFRL1 OLFM1 OLFM1 TGFB2 TGFB2 NOTCH1 NOTCH1 ACVR1 ACVR1 GATA5 GATA5 TBX5 TBX5 ENSCSAP00000012589 ENSCSAP00000012589 SLIT2 SLIT2 GATA4 GATA4 RB1 RB1 SMAD4 SMAD4 ELN ELN NFATC1 NFATC1 TGFB1 TGFB1 ZFPM1 ZFPM1 HEY2 HEY2 EFNA1 EFNA1 NOTCH2 NOTCH2 CCN1 CCN1 TIE1 TIE1 HEYL HEYL NPPA NPPA MTOR MTOR SOX4 SOX4 GJA5 GJA5 DCHS1 DCHS1 SOX9 SOX9 ENSCSAP00000002167 ENSCSAP00000002167 ROBO2 ROBO2 ROBO1 ROBO1 NOS3 NOS3 ROCK2 ROCK2 DLL4 DLL4 SCX SCX EMILIN1 EMILIN1 NKX2-5 NKX2-5 TGFBR2 TGFBR2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SLIT3Slit guidance ligand 3. (1320 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1764 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
GATA3GATA binding protein 3. (443 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
STRA6Stimulated by retinoic acid 6. (659 aa)
MDM4Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (490 aa)
MEF2CMyocyte enhancer factor 2C. (446 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TBX20T-box transcription factor 20. (447 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
FGFRL1Fibroblast growth factor receptor like 1. (474 aa)
OLFM1Olfactomedin 1. (328 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
NOTCH1Notch receptor 1. (2555 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
GATA5GATA binding protein 5. (366 aa)
TBX5T-box transcription factor 5. (518 aa)
ENSCSAP00000012589LRRNT domain-containing protein. (132 aa)
SLIT2Slit guidance ligand 2. (1332 aa)
GATA4GATA binding protein 4. (442 aa)
RB1RB transcriptional corepressor 1. (928 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ELNUncharacterized protein. (68 aa)
NFATC1Nuclear factor of activated T cells 1. (929 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ZFPM1Zinc finger protein, FOG family member 1. (992 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
NOTCH2Notch receptor 2. (2471 aa)
CCN1Cellular communication network factor 1. (381 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
NPPANatriuretic peptide A. (153 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
SOX4Transcription factor SOX. (475 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (358 aa)
DCHS1Dachsous cadherin-related 1. (3296 aa)
SOX9SRY-box transcription factor 9. (509 aa)
ENSCSAP00000002167Ig-like domain-containing protein. (131 aa)
ROBO2Roundabout guidance receptor 2. (1235 aa)
ROBO1Uncharacterized protein. (1466 aa)
NOS3Nitric oxide synthase 3. (867 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
SCXScleraxis bHLH transcription factor. (201 aa)
EMILIN1Elastin microfibril interfacer 1. (860 aa)
NKX2-5NK2 homeobox 5. (324 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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