STRINGSTRING
DLL4 DLL4 HEY1 HEY1 GATA3 GATA3 JAG1 JAG1 HEY2 HEY2 EMILIN1 EMILIN1 NKX2-5 NKX2-5 NPPA NPPA HEYL HEYL TIE1 TIE1 EFNA1 EFNA1 TGFB1 TGFB1 NFATC1 NFATC1 ELN ELN RB1 RB1 GATA4 GATA4 SLIT2 SLIT2 ENSCSAP00000012589 ENSCSAP00000012589 SMAD6 SMAD6 SLIT3 SLIT3 SNAI2 SNAI2 BMP4 BMP4 TBX20 TBX20 SNAI1 SNAI1 NOTCH1 NOTCH1 GATA5 GATA5 ENSCSAP00000002167 ENSCSAP00000002167 ROBO2 ROBO2 ROBO1 ROBO1 NOS3 NOS3 ROCK2 ROCK2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
GATA3GATA binding protein 3. (443 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
EMILIN1Elastin microfibril interfacer 1. (860 aa)
NKX2-5NK2 homeobox 5. (324 aa)
NPPANatriuretic peptide A. (153 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
NFATC1Nuclear factor of activated T cells 1. (929 aa)
ELNUncharacterized protein. (68 aa)
RB1RB transcriptional corepressor 1. (928 aa)
GATA4GATA binding protein 4. (442 aa)
SLIT2Slit guidance ligand 2. (1332 aa)
ENSCSAP00000012589LRRNT domain-containing protein. (132 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
SLIT3Slit guidance ligand 3. (1320 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TBX20T-box transcription factor 20. (447 aa)
SNAI1Snail family transcriptional repressor 1. (264 aa)
NOTCH1Notch receptor 1. (2555 aa)
GATA5GATA binding protein 5. (366 aa)
ENSCSAP00000002167Ig-like domain-containing protein. (131 aa)
ROBO2Roundabout guidance receptor 2. (1235 aa)
ROBO1Uncharacterized protein. (1466 aa)
NOS3Nitric oxide synthase 3. (867 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1383 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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