STRINGSTRING
HEYL HEYL FGFR2 FGFR2 MYBPC3 MYBPC3 SMARCD3 SMARCD3 PKP2 PKP2 DSP DSP DLL4 DLL4 HEG1 HEG1 FOXH1 FOXH1 NKX2-5 NKX2-5 TGFBR2 TGFBR2 RYR2 RYR2 BMPR1A BMPR1A HAND1 HAND1 TGFBR1 TGFBR1 ZFPM2 ZFPM2 SEMA3C SEMA3C GRHL2 GRHL2 HEY1 HEY1 GATA3 GATA3 TNNC1 TNNC1 JAG1 JAG1 ENG ENG TNNT2 TNNT2 TNNI1 TNNI1 HIF1A HIF1A CHD7 CHD7 MEF2C MEF2C TBX20 TBX20 BMP10 BMP10 LRP2 LRP2 PROX1 PROX1 PTCD2 PTCD2 TGFB2 TGFB2 NRG1 NRG1 NOTCH1 NOTCH1 MYH7 MYH7 MYH6 MYH6 MYL3 MYL3 HEY2 HEY2 ISL1 ISL1 GATA4 GATA4 MESP1 MESP1 SMAD7 SMAD7 MYL10 MYL10 SMAD4 SMAD4 TGFB1 TGFB1 GSK3A GSK3A EDNRA EDNRA SFRP2 SFRP2 NPY5R NPY5R ENSCSAP00000014858 ENSCSAP00000014858 PPP1R13L PPP1R13L CPE CPE FOXF1 FOXF1 HAND2 HAND2 MED1 MED1 MYL2 MYL2 TBX5 TBX5 TNNI3 TNNI3 COL11A1 COL11A1 TGFBR3 TGFBR3 NOG NOG NPY2R NPY2R SOX11 SOX11 FOXC2 FOXC2 SOX4 SOX4 FOXC1 FOXC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
MYBPC3Myosin binding protein C, cardiac. (1266 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (470 aa)
PKP2Plakophilin 2. (837 aa)
DSPDesmoplakin. (2871 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
HEG1Heart development protein with EGF like domains 1. (1323 aa)
FOXH1Forkhead box H1. (365 aa)
NKX2-5NK2 homeobox 5. (324 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
RYR2Ryanodine receptor 2. (4906 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
HAND1Heart and neural crest derivatives expressed 1. (215 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
ZFPM2Zinc finger protein, FOG family member 2. (940 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
GATA3GATA binding protein 3. (443 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (161 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
ENGEndoglin. (658 aa)
TNNT2Troponin T2, cardiac type. (302 aa)
TNNI1Troponin I1, slow skeletal type. (183 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2998 aa)
MEF2CMyocyte enhancer factor 2C. (446 aa)
TBX20T-box transcription factor 20. (447 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
LRP2LDL receptor related protein 2. (3861 aa)
PROX1Prospero homeobox 1. (737 aa)
PTCD2Pentatricopeptide repeat domain 2. (383 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
NRG1Neuregulin 1. (467 aa)
NOTCH1Notch receptor 1. (2555 aa)
MYH7Myosin heavy chain 7; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1501 aa)
MYH6Myosin heavy chain 6; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1942 aa)
MYL3Myosin light chain 3. (197 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
ISL1ISL LIM homeobox 1. (349 aa)
GATA4GATA binding protein 4. (442 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (272 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
MYL10Myosin light chain 10. (136 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
GSK3AGlycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
NPY5RNeuropeptide Y receptor Y5. (287 aa)
ENSCSAP00000014858Uncharacterized protein. (451 aa)
PPP1R13LUncharacterized protein. (518 aa)
CPECarboxypeptidase E. (476 aa)
FOXF1Forkhead box F1. (354 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1580 aa)
MYL2Myosin light chain 2. (166 aa)
TBX5T-box transcription factor 5. (518 aa)
TNNI3Troponin I3, cardiac type. (210 aa)
COL11A1Collagen type XI alpha 1 chain. (1806 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
NPY2RNeuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family. (381 aa)
SOX11Transcription factor SOX. (441 aa)
FOXC2Forkhead box C2. (501 aa)
SOX4Transcription factor SOX. (475 aa)
FOXC1Forkhead box C1. (552 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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