STRINGSTRING
TSPOAP1 TSPOAP1 RYR1 RYR1 CACNG5 CACNG5 CACNG4 CACNG4 CACNG1 CACNG1 PKD2 PKD2 CALHM1 CALHM1 CACNA1G CACNA1G CACNB1 CACNB1 CACNG7 CACNG7 CACNG8 CACNG8 CACNG6 CACNG6 CACHD1 CACHD1 CATSPER4 CATSPER4 CNR2 CNR2 CNR1 CNR1 CACNA1E CACNA1E ITGAV ITGAV CACNA2D1 CACNA2D1 CACNA1H CACNA1H CACNA2D4 CACNA2D4 CACNA1C CACNA1C TMC2 TMC2 TPCN2 TPCN2 TMC1 TMC1 CATSPER1 CATSPER1 CACNG2 CACNG2 CDK5 CDK5 CACNB2 CACNB2 CACNA1F CACNA1F CACNA2D3 CACNA2D3 CACNA1D CACNA1D CATSPER3 CATSPER3 OPRM1 OPRM1 TRPV1 TRPV1 CACNA1B CACNA1B CACNB4 CACNB4 ENSCSAP00000010833 ENSCSAP00000010833 CACNA2D2 CACNA2D2 CACNA1S CACNA1S CACNA1A CACNA1A CACNB3 CACNB3 CACNA1I CACNA1I
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TSPOAP1TSPO associated protein 1. (1858 aa)
RYR1Ryanodine receptor 1. (4303 aa)
CACNG5Calcium voltage-gated channel auxiliary subunit gamma 5. (278 aa)
CACNG4Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa)
CACNG1Voltage-dependent calcium channel gamma-1 subunit; Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents in skeletal muscle. Regulates channel inactivation kinetics. (222 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (859 aa)
CALHM1Calcium homeostasis modulator 1. (346 aa)
CACNA1GVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2186 aa)
CACNB1Calcium voltage-gated channel auxiliary subunit beta 1. (643 aa)
CACNG7Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa)
CACNG8Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (421 aa)
CACNG6Voltage-dependent calcium channel gamma-6 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (261 aa)
CACHD1Cache domain containing 1. (1223 aa)
CATSPER4Cation channel sperm associated 4. (472 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (360 aa)
CNR1Cannabinoid receptor 1; G-protein coupled receptor for cannabinoids (eCBs), including N-arachidonoylethanolamide (also called anandamide or AEA) and 2- arachidonoylglycerol (2-AG). Mediates many cannabinoid-induced effects, acting, among others, on food intake, memory loss, gastrointestinal motility, catalepsy, ambulatory activity, anxiety, chronic pain. Signaling typically involves reduction in cyclic AMP. In the hypothalamus, may have a dual effect on mitochondrial respiration depending upon the agonist dose and possibly upon the cell type. Increases respiration at low doses, while d [...] (472 aa)
CACNA1EVoltage-dependent R-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. (2306 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
CACNA2D1Calcium voltage-gated channel auxiliary subunit alpha2delta 1. (962 aa)
CACNA1HCalcium voltage-gated channel subunit alpha1 H. (2240 aa)
CACNA2D4Calcium voltage-gated channel auxiliary subunit alpha2delta 4. (1137 aa)
CACNA1CCalcium voltage-gated channel subunit alpha1 C. (1898 aa)
TMC2Transmembrane channel-like protein. (879 aa)
TPCN2Two pore segment channel 2. (752 aa)
TMC1Transmembrane channel-like protein. (761 aa)
CATSPER1Cation channel sperm associated 1. (758 aa)
CACNG2Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
CDK5Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (224 aa)
CACNB2Calcium voltage-gated channel auxiliary subunit beta 2. (612 aa)
CACNA1FIon_trans domain-containing protein. (233 aa)
CACNA2D3Calcium voltage-gated channel auxiliary subunit alpha2delta 3. (1034 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2036 aa)
CATSPER3Cation channel sperm associated 3. (398 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (400 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Belongs to the transient receptor (TC 1.A.4) family. (828 aa)
CACNA1BVoltage-dependent N-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1B gives rise to N-type calcium currents. (2342 aa)
CACNB4Calcium voltage-gated channel auxiliary subunit beta 4. (486 aa)
ENSCSAP00000010833Uncharacterized protein. (176 aa)
CACNA2D2Calcium voltage-gated channel auxiliary subunit alpha2delta 2. (1074 aa)
CACNA1SVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1873 aa)
CACNA1AVoltage-dependent P/Q-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q- type calcium currents. (1363 aa)
CACNB3Calcium voltage-gated channel auxiliary subunit beta 3. (484 aa)
CACNA1IVoltage-dependent T-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. This channel gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite ne [...] (2234 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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