STRINGSTRING
ACKR3 ACKR3 PICALM PICALM ARRB1 ARRB1 FCHSD2 FCHSD2 LRP3 LRP3 INPP5F INPP5F LRP1 LRP1 SPHK1 SPHK1 EPN3 EPN3 FCHO1 FCHO1 EPS15L1 EPS15L1 CLTC CLTC SH3BP4 SH3BP4 AP2B1 AP2B1 DGKD DGKD LDLR LDLR DNM2 DNM2 DNM1L DNM1L AP1S3 AP1S3 ATAT1 ATAT1 C6orf136 C6orf136 OCRL OCRL ITSN2 ITSN2 TNK2 TNK2 TFRC TFRC VLDLR VLDLR APP APP CLTB CLTB CTTN CTTN SYNJ1 SYNJ1 ITSN1 ITSN1 ADCY8 ADCY8 AMN AMN BMPR2 BMPR2 AP2A2 AP2A2 TF TF CLTA CLTA CDHR5 CDHR5 SELE SELE CLTCL1 CLTCL1 LRP12 LRP12 SLC2A4 SLC2A4 NUMB NUMB CUBN CUBN ARRB2 ARRB2 AP2M1 AP2M1 STON1 STON1 CLHC1 CLHC1 FNBP1 FNBP1 AP1S2 AP1S2 AAK1 AAK1 LRP2 LRP2 FCHO2 FCHO2 LRP10 LRP10 DAB2 DAB2 REPS1 REPS1 MYO6 MYO6 AP1S1 AP1S1 RAMP2 RAMP2 ENSCSAP00000015592 ENSCSAP00000015592 ENSCSAP00000018951 ENSCSAP00000018951 AP2A1 AP2A1 RAB35 RAB35 HIP1R HIP1R EPN1 EPN1 SORT1 SORT1 SGIP1 SGIP1 EPS15 EPS15 NECAP2 NECAP2 SLC18A3 SLC18A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (362 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (660 aa)
ARRB1Arrestin beta 1. (418 aa)
FCHSD2FCH and double SH3 domains 2. (740 aa)
LRP3LDL receptor related protein 3. (770 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1133 aa)
LRP1LDL receptor related protein 1. (4544 aa)
SPHK1Sphingosine kinase 1. (472 aa)
EPN3Epsin 3. (640 aa)
FCHO1FCH domain only 1. (810 aa)
EPS15L1Epidermal growth factor receptor pathway substrate 15 like 1. (926 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1495 aa)
SH3BP4SH3 domain binding protein 4. (963 aa)
AP2B1AP complex subunit beta. (951 aa)
DGKDDiacylglycerol kinase. (1156 aa)
LDLRLow density lipoprotein receptor. (767 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
DNM1LDynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa)
AP1S3AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (154 aa)
ATAT1Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] (487 aa)
C6orf136Chromosome 6 open reading frame 136. (315 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (884 aa)
ITSN2Intersectin 2. (1684 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1065 aa)
TFRCTransferrin receptor. (774 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
APPAmyloid beta precursor protein. (770 aa)
CLTBClathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (211 aa)
CTTNCortactin. (550 aa)
SYNJ1Synaptojanin 1. (1311 aa)
ITSN1Intersectin 1. (1649 aa)
ADCY8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1037 aa)
AMNAmnion associated transmembrane protein. (484 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
AP2A2AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (939 aa)
TFTransferrin; Belongs to the transferrin family. (698 aa)
CLTAClathrin light chain A. (218 aa)
CDHR5Cadherin related family member 5. (787 aa)
SELESelectin E. (610 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1914 aa)
LRP12LDL receptor related protein 12. (859 aa)
SLC2A4Solute carrier family 2 member 4; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (509 aa)
NUMBNUMB endocytic adaptor protein. (652 aa)
CUBNCubilin. (3623 aa)
ARRB2Arrestin beta 2. (409 aa)
AP2M1Adaptor related protein complex 2 subunit mu 1; Belongs to the adaptor complexes medium subunit family. (251 aa)
STON1Stonin-1; May be involved in the endocytic machinery. (735 aa)
CLHC1Clathrin heavy chain linker domain-containing protein 1. (586 aa)
FNBP1Formin binding protein 1. (647 aa)
AP1S2AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (202 aa)
AAK1AP2 associated kinase 1. (909 aa)
LRP2LDL receptor related protein 2. (3861 aa)
FCHO2FCH domain only 2. (811 aa)
LRP10LDL receptor related protein 10. (716 aa)
DAB2DAB adaptor protein 2. (770 aa)
REPS1RALBP1 associated Eps domain containing 1. (796 aa)
MYO6Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1262 aa)
AP1S1AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (158 aa)
RAMP2Receptor activity modifying protein 2. (175 aa)
ENSCSAP00000015592Adaptin_N domain-containing protein. (132 aa)
ENSCSAP00000018951Uncharacterized protein. (355 aa)
AP2A1Alpha_adaptinC2 domain-containing protein. (817 aa)
RAB35RAB35, member RAS oncogene family. (201 aa)
HIP1RHuntingtin interacting protein 1 related. (1056 aa)
EPN1Epsin 1. (576 aa)
SORT1Sortilin. (831 aa)
SGIP1SH3 domain GRB2 like endophilin interacting protein 1. (828 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (897 aa)
NECAP2NECAP endocytosis associated 2. (263 aa)
SLC18A3Solute carrier family 18 member A3. (532 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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