STRINGSTRING
XPC XPC MSH3 MSH3 TP73 TP73 MCM9 MCM9 SETD2 SETD2 MUTYH MUTYH MSH4 MSH4 LIG1 LIG1 PMS2 PMS2 UPK3B UPK3B ERCC1 ERCC1 TDG TDG ABL1 ABL1 MLH1 MLH1 RPA1 RPA1 MSH6 MSH6 MSH2 MSH2 PCNA PCNA RPA3 RPA3 PMS1 PMS1 MLH3 MLH3 POLD3 POLD3 EXO1 EXO1 MSH5 MSH5 RNASEH2C RNASEH2C RNASEH2A RNASEH2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
XPCXPC complex subunit, DNA damage recognition and repair factor. (888 aa)
MSH3DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1125 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (637 aa)
MCM9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1142 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2565 aa)
MUTYHAdenine DNA glycosylase; Adenine glycosylase active on G-A mispairs. (618 aa)
MSH4MutS homolog 4. (935 aa)
LIG1DNA ligase. (919 aa)
PMS2PMS1 homolog 2, mismatch repair system component. (862 aa)
UPK3BUroplakin 3B. (276 aa)
ERCC1ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa)
TDGThymine DNA glycosylase. (267 aa)
ABL1Tyrosine-protein kinase. (1130 aa)
MLH1MutL homolog 1. (756 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1360 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (933 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
RPA3Replication protein A3. (121 aa)
PMS1PMS1 homolog 1, mismatch repair system component. (931 aa)
MLH3MutL homolog 3. (1237 aa)
POLD3Uncharacterized protein. (466 aa)
EXO1Exonuclease 1. (845 aa)
MSH5DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (850 aa)
RNASEH2CRibonuclease H2 subunit C. (164 aa)
RNASEH2ARibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (300 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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