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| | PTGIS | Prostaglandin I2 synthase; Belongs to the cytochrome P450 family. (492 aa) |
| | OLAH | Oleoyl-ACP hydrolase. (323 aa) |
| | DECR2 | 2,4-dienoyl-CoA reductase 2. (292 aa) |
| | HACD1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa) |
| | GPX4 | Uncharacterized protein. (109 aa) |
| | QKI | QKI, KH domain containing RNA binding. (341 aa) |
| | ENSCSAP00000008436 | Uncharacterized protein. (665 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (663 aa) |
| | LIPC | Lipase C, hepatic type. (499 aa) |
| | CD74 | CD74 molecule. (294 aa) |
| | PNPLA8 | Patatin like phospholipase domain containing 8. (782 aa) |
| | MIF | Macrophage migration inhibitory factor. (115 aa) |
| | ALOX15B | Arachidonate 15-lipoxygenase type B. (676 aa) |
| | PCCB | Propionyl-CoA carboxylase subunit beta. (539 aa) |
| | ALOX12B | Arachidonate 12-lipoxygenase, 12R type. (701 aa) |
| | ALOXE3 | Arachidonate lipoxygenase 3. (714 aa) |
| | XBP1 | X-box binding protein 1. (261 aa) |
| | ACSM4 | Acyl-CoA synthetase medium chain family member 4. (580 aa) |
| | ACSBG2 | Acyl-CoA synthetase bubblegum family member 2. (639 aa) |
| | OXSM | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (460 aa) |
| | HACD4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (195 aa) |
| | ABHD1 | Abhydrolase domain containing 1. (411 aa) |
| | HSD17B8 | Hydroxysteroid 17-beta dehydrogenase 8. (257 aa) |
| | PLP1 | Proteolipid protein 1. (277 aa) |
| | PECR | Peroxisomal trans-2-enoyl-CoA reductase. (303 aa) |
| | LIPI | Lipase I. (415 aa) |
| | GSTP1 | Glutathione S-transferase pi 1. (383 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (464 aa) |
| | MGLL | Monoglyceride lipase. (339 aa) |
| | PLA2G4F | Phospholipase A2. (853 aa) |
| | LTC4S | Leukotriene C4 synthase. (150 aa) |
| | TBXAS1 | Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (534 aa) |
| | PLA2G10 | Phospholipase A(2). (165 aa) |
| | ACSM5 | Acyl-CoA synthetase medium chain family member 5. (582 aa) |
| | ACSM2B | Uncharacterized protein. (577 aa) |
| | ACSM1 | Acyl-CoA synthetase medium chain family member 1. (577 aa) |
| | ACSM3 | Acyl-CoA synthetase medium chain family member 3. (586 aa) |
| | HACD2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (161 aa) |
| | EDN1 | Endothelin 1. (211 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (296 aa) |
| | ASAH2 | Neutral ceramidase. (780 aa) |
| | NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (112 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (524 aa) |
| | FADS3 | Fatty acid desaturase 3. (445 aa) |
| | FADS2 | Fatty acid desaturase 2. (444 aa) |
| | FADS1 | Fatty acid desaturase 1. (501 aa) |
| | TECR | Trans-2,3-enoyl-CoA reductase. (308 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (331 aa) |
| | CYP2C9 | Uncharacterized protein; Belongs to the cytochrome P450 family. (468 aa) |
| | CYP2C8 | Cytochrome P450 family 2 subfamily C member 8; Belongs to the cytochrome P450 family. (490 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2346 aa) |
| | ENSCSAP00000002230 | FA_desaturase domain-containing protein. (370 aa) |
| | MCAT | Malonyl-CoA-acyl carrier protein transacylase. (390 aa) |
| | SCD | Stearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa) |
| | HSD17B12 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa) |
| | TECRL | Trans-2,3-enoyl-CoA reductase like. (326 aa) |
| | ARMC7 | Armadillo repeat containing 7. (198 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) |
| | SCD5 | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (344 aa) |
| | HPGDS | Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein. (192 aa) |
| | ALOX15 | Arachidonate 15-lipoxygenase. (610 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (572 aa) |
| | PLA2G4A | Phospholipase A2. (749 aa) |
| | PTGS1 | Prostaglandin-endoperoxide synthase 1. (599 aa) |
| | LOC103246731 | Uncharacterized protein. (741 aa) |
| | TMEM196 | Uncharacterized protein. (104 aa) |
| | AKR1C3 | Aldo-keto reductase family 1 member C3. (326 aa) |
| | PTGES2 | Prostaglandin E synthase 2; Belongs to the GST superfamily. (377 aa) |
| | LIPH | Lipase H. (451 aa) |
| | PTGES | Prostaglandin E synthase. (145 aa) |
| | HACD3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (362 aa) |
| | SUGCT | Succinyl-CoA:glutarate-CoA transferase. (332 aa) |
| | ELOVL7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa) |
| | PTGDS | Lipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (190 aa) |
| | DEGS1 | Delta 4-desaturase, sphingolipid 1. (323 aa) |
| | THNSL2 | Threonine synthase like 2. (519 aa) |
| | LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (501 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (372 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa) |
| | ABHD3 | Abhydrolase domain containing 3. (410 aa) |
| | DAGLB | Diacylglycerol lipase beta. (668 aa) |
| | CYP3A4 | Cytochrome P450 family 3 subfamily A member 4; Belongs to the cytochrome P450 family. (359 aa) |
| | LIPG | Lipase G, endothelial type. (500 aa) |
| | ACSS1 | Acyl-CoA synthetase short chain family member 1. (399 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | BRCA1 | Uncharacterized protein. (663 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (493 aa) |
| | HSDL1 | Hydroxysteroid dehydrogenase like 1. (330 aa) |
| | CBR4 | Carbonyl reductase 4. (237 aa) |
| | ACLY | ATP citrate lyase. (603 aa) |
| | ACSF3 | Acyl-CoA synthetase family member 3. (576 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2462 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | PLA2G1B | Phospholipase A(2). (148 aa) |
| | HNF1A | HNF1 homeobox A. (632 aa) |
| | FASN | Fatty acid synthase. (2510 aa) |
| | GSTM5 | Glutathione S-transferase mu 5. (218 aa) |
| | GSTM4 | Glutathione S-transferase mu 4. (218 aa) |
| | ABCD3 | ATP binding cassette subfamily D member 3. (659 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | EDN2 | Endothelin 2. (178 aa) |
| | MECR | Mitochondrial trans-2-enoyl-CoA reductase. (373 aa) |
| | ACOT7 | Acyl-CoA thioesterase 7. (370 aa) |
| | PRXL2B | Peroxiredoxin like 2B. (230 aa) |
| | HTD2 | Hydroxyacyl-thioester dehydratase type 2. (168 aa) |
| | THNSL1 | Threonine synthase like 1. (743 aa) |
