STRINGSTRING
ATG4C ATG4C UFC1 UFC1 MOAP1 MOAP1 BECN2 BECN2 NHLRC1 NHLRC1 ENSCSAP00000018379 ENSCSAP00000018379 FUNDC1 FUNDC1 TMEM74 TMEM74 ENSCSAP00000018133 ENSCSAP00000018133 UBQLN2 UBQLN2 EMC6 EMC6 PARK7 PARK7 MTOR MTOR MFN2 MFN2 ATP13A2 ATP13A2 PINK1 PINK1 STX12 STX12 TMEM39B TMEM39B TMEM59 TMEM59 PRKAA2 PRKAA2 FNBP1L FNBP1L KIAA1324 KIAA1324 DRAM2 DRAM2 CHMP2A CHMP2A PTPN22 PTPN22 TMEM150B TMEM150B LIX1L LIX1L PGAM5 PGAM5 S100A9 S100A9 S100A8 S100A8 SNAPIN SNAPIN ULK1 ULK1 GBA GBA SYT11 SYT11 VPS37B VPS37B UBQLN4 UBQLN4 WDR45B WDR45B VPS33A VPS33A HGS HGS EI24 EI24 CHMP6 CHMP6 RNF213 RNF213 HSPA8 HSPA8 TBC1D17 TBC1D17 IFI16 IFI16 SNF8 SNF8 CALCOCO2 CALCOCO2 VPS11 VPS11 TRAPPC4 TRAPPC4 CD84 CD84 PIP4K2B PIP4K2B ATP2A2 ATP2A2 SPATA33 SPATA33 CHMP1A CHMP1A USP30 USP30 RAB39A RAB39A RNF166 RNF166 MAP1LC3B MAP1LC3B IRF8 IRF8 USP10 USP10 RETREG3 RETREG3 DRAM1 DRAM1 VPS25 VPS25 BECN1 BECN1 LRBA LRBA NBR1 NBR1 RAB33B RAB33B MFSD8 MFSD8 LAMP2 LAMP2 SRPX SRPX FIS1 FIS1 EPG5 EPG5 PIK3C3 PIK3C3 TRAPPC8 TRAPPC8 UFM1 UFM1 AP4M1 AP4M1 FOXO1 FOXO1 SMURF1 SMURF1 TMEM130 TMEM130 RUBCNL RUBCNL TECPR1 TECPR1 TAZ TAZ NPC1 NPC1 RMC1 RMC1 VPS36 VPS36 WIPI2 WIPI2 RAB12 RAB12 DAP DAP RETREG1 RETREG1 EPM2A EPM2A TGFBRAP1 TGFBRAP1 ENSCSAP00000012988 ENSCSAP00000012988 PRKAA1 PRKAA1 C5orf51 C5orf51 VPS37A VPS37A RGS19 RGS19 TRIM17 TRIM17 ENSCSAP00000012530 ENSCSAP00000012530 CHMP3 CHMP3 CHMP7 CHMP7 VAMP8 VAMP8 TBC1D14 TBC1D14 STAM2 STAM2 TM9SF1 TM9SF1 CHMP4A CHMP4A CLU CLU EVA1A EVA1A SEC16A SEC16A AUP1 AUP1 ENSCSAP00000011477 ENSCSAP00000011477 WDR41 WDR41 ARSB ARSB VPS41 VPS41 YOD1 YOD1 SLC25A46 SLC25A46 ATG10 ATG10 ATG12 ATG12 RAB1A RAB1A ABL1 ABL1 ATG5 ATG5 RB1CC1 RB1CC1 ATG14 ATG14 FBXL4 FBXL4 PIK3C2B PIK3C2B UBXN2B UBXN2B NOD1 NOD1 UFL1 UFL1 ULK3 ULK3 LIX1 LIX1 PJVK PJVK ARL8A ARL8A TEX264 TEX264 WDR81 WDR81 LRSAM1 LRSAM1 SRC SRC RAB23 RAB23 MAP2K5 MAP2K5 VPS16 VPS16 DDRGK1 DDRGK1 VTI1B VTI1B SNAP29 SNAP29 TBC1D25 TBC1D25 CHMP4C CHMP4C HDAC6 HDAC6 OPTN OPTN ZFYVE26 ZFYVE26 USP13 USP13 STING1 STING1 WDR45 WDR45 RIPK2 RIPK2 PSEN1 PSEN1 ENSCSAP00000008892 ENSCSAP00000008892 STAM STAM TP53INP1 TP53INP1 PIP4K2A PIP4K2A HERC1 HERC1 SNX30 SNX30 STUB1 STUB1 STK11 STK11 PRKN PRKN WDR24 WDR24 CHMP4B CHMP4B MAP1LC3A MAP1LC3A SEC16B SEC16B TP53INP2 TP53INP2 PHF23 PHF23 GABARAP GABARAP ACBD5 ACBD5 TP53 TP53 TFEB TFEB OGT OGT TIGAR TIGAR PIK3CB PIK3CB STX17 STX17 ARL8B ARL8B MTMR14 MTMR14 NSFL1C NSFL1C UBA5 UBA5 ATG2B ATG2B UBXN6 UBXN6 PIK3R4 PIK3R4 VCP VCP WDFY4 WDFY4 TECPR2 TECPR2 PHB2 PHB2 CHMP5 CHMP5 TOLLIP TOLLIP XBP1 XBP1 TBC1D5 TBC1D5 ATG7 ATG7 ILRUN ILRUN C9orf72 C9orf72 GPR137B GPR137B LGALS8 LGALS8 PLAA PLAA MTMR3 MTMR3 PACS2 PACS2 ENSCSAP00000005633 ENSCSAP00000005633 MAP1LC3C MAP1LC3C GABARAPL1 GABARAPL1 PMP22 PMP22 RUFY4 RUFY4 RAB24 RAB24 ATG4A ATG4A TCIRG1 TCIRG1 RNF185 RNF185 RAB43 RAB43 MCOLN1 MCOLN1 ANXA7 ANXA7 RAB7A RAB7A VPS39 VPS39 RUBCN RUBCN VPS28 VPS28 CLEC16A CLEC16A SQSTM1 SQSTM1 UBXN2A UBXN2A FBXO7 FBXO7 RAB19 RAB19 RETREG2 RETREG2 ATG9A ATG9A HMOX1 HMOX1 RAB1B RAB1B SMCR8 SMCR8 ZKSCAN3 ZKSCAN3 ULK2 ULK2 VPS13A VPS13A VPS51 VPS51 VPS18 VPS18 NRBF2 NRBF2 ATG2A ATG2A LRRK2 LRRK2 GPR137 GPR137 ATG4D ATG4D TMEM39A TMEM39A MARK2 MARK2 ATG9B ATG9B ATG3 ATG3 FUNDC2 FUNDC2 RAB39B RAB39B ATG16L1 ATG16L1 CLN3 CLN3 MAPK3 MAPK3 TMBIM6 TMBIM6 BCAS3 BCAS3 CHMP2B CHMP2B VMP1 VMP1 CLTC CLTC ATG101 ATG101 RAB8A RAB8A ATG4B ATG4B ATG13 ATG13 AMBRA1 AMBRA1 MVB12A MVB12A MAP1S MAP1S NOD2 NOD2 RNF41 RNF41 VTI1A VTI1A TSG101 TSG101 HDAC10 HDAC10 SPATA18 SPATA18 C19orf12 C19orf12 ENSCSAP00000001172 ENSCSAP00000001172 ARSA ARSA BAG3 BAG3 STBD1 STBD1 GRAMD1A GRAMD1A SBF2 SBF2 TMEM41B TMEM41B BNIP3 BNIP3 WDFY3 WDFY3 ARFIP2 ARFIP2 TRIM5 TRIM5 WIPI1 WIPI1 VPS4A VPS4A ATG16L2 ATG16L2 CISD2 CISD2 UVRAG UVRAG TMEM208 TMEM208 SYNPO2 SYNPO2 PLEKHM1 PLEKHM1 GABARAPL2 GABARAPL2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATG4CCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (458 aa)
UFC1Ubiquitin-fold modifier-conjugating enzyme 1; E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage. (167 aa)
MOAP1Modulator of apoptosis 1. (351 aa)
BECN2Beclin 2. (440 aa)
NHLRC1NHL repeat containing E3 ubiquitin protein ligase 1. (395 aa)
ENSCSAP00000018379Uncharacterized protein. (212 aa)
FUNDC1Uncharacterized protein. (155 aa)
TMEM74Transmembrane protein 74. (305 aa)
ENSCSAP00000018133Uncharacterized protein. (215 aa)
UBQLN2Ubiquilin 2. (624 aa)
EMC6ER membrane protein complex subunit 6. (110 aa)
PARK7Parkinsonism associated deglycase. (189 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2549 aa)
MFN2Mitofusin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (757 aa)
ATP13A2Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1175 aa)
PINK1PTEN induced kinase 1. (581 aa)
STX12Syntaxin 12; Belongs to the syntaxin family. (276 aa)
TMEM39BTransmembrane protein 39B. (492 aa)
TMEM59Transmembrane protein 59. (323 aa)
PRKAA2Non-specific serine/threonine protein kinase. (552 aa)
FNBP1LFormin binding protein 1 like. (547 aa)
KIAA1324KIAA1324. (987 aa)
DRAM2DNA damage regulated autophagy modulator 2. (266 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (807 aa)
TMEM150BTransmembrane protein 150B. (233 aa)
LIX1LLimb and CNS expressed 1 like. (337 aa)
PGAM5PGAM family member 5, mitochondrial serine/threonine protein phosphatase. (285 aa)
S100A9Protein S100; Belongs to the S-100 family. (114 aa)
S100A8Protein S100; Belongs to the S-100 family. (93 aa)
SNAPINSNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1070 aa)
GBAGlucosylceramidase. (536 aa)
SYT11Synaptotagmin 11. (431 aa)
VPS37BVPS37B subunit of ESCRT-I. (285 aa)
UBQLN4Ubiquitin-like domain-containing protein. (308 aa)
WDR45BWD repeat domain 45B. (344 aa)
VPS33AUncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (534 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
EI24EI24 autophagy associated transmembrane protein. (340 aa)
CHMP6Charged multivesicular body protein 6. (201 aa)
RNF213Ring finger protein 213. (5249 aa)
HSPA8Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family. (646 aa)
TBC1D17TBC1 domain family member 17. (648 aa)
IFI16Interferon gamma inducible protein 16. (728 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
CALCOCO2Calcium binding and coiled-coil domain 2. (446 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa)
TRAPPC4Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (219 aa)
CD84CD84 molecule. (328 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (352 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (997 aa)
SPATA33Spermatogenesis associated 33. (108 aa)
CHMP1ACharged multivesicular body protein 1A. (196 aa)
USP30Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (517 aa)
RAB39ARAB39A, member RAS oncogene family. (217 aa)
RNF166Ring finger protein 166. (237 aa)
MAP1LC3BUncharacterized protein. (125 aa)
IRF8Interferon regulatory factor 8. (426 aa)
USP10Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (792 aa)
RETREG3Reticulophagy regulator family member 3. (466 aa)
DRAM1DNA damage regulated autophagy modulator 1. (238 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
BECN1Beclin 1. (450 aa)
LRBALPS responsive beige-like anchor protein. (2113 aa)
NBR1NBR1 autophagy cargo receptor. (967 aa)
RAB33BRAB33B, member RAS oncogene family. (229 aa)
MFSD8Major facilitator superfamily domain containing 8. (431 aa)
LAMP2Lysosomal associated membrane protein 2. (410 aa)
SRPXSushi repeat containing protein X-linked. (439 aa)
FIS1Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. (152 aa)
EPG5Ectopic P-granules autophagy protein 5 homolog. (2579 aa)
PIK3C3Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa)
TRAPPC8Trafficking protein particle complex 8. (1435 aa)
UFM1Ubiquitin fold modifier 1. (84 aa)
AP4M1AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (453 aa)
FOXO1Forkhead box O1. (655 aa)
SMURF1E3 ubiquitin-protein ligase. (728 aa)
TMEM130Transmembrane protein 130. (423 aa)
RUBCNLRubicon like autophagy enhancer. (663 aa)
TECPR1Tectonin beta-propeller repeat containing 1. (1165 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (262 aa)
NPC1NPC intracellular cholesterol transporter 1. (1278 aa)
RMC1Regulator of MON1-CCZ1. (657 aa)
VPS36Vacuolar protein sorting 36 homolog. (386 aa)
WIPI2WD repeat domain, phosphoinositide interacting 2. (443 aa)
RAB12RAB12, member RAS oncogene family. (346 aa)
DAPDeath associated protein. (162 aa)
RETREG1Reticulophagy regulator 1. (497 aa)
EPM2AEPM2A glucan phosphatase, laforin. (331 aa)
TGFBRAP1Transforming growth factor beta receptor associated protein 1. (860 aa)
ENSCSAP00000012988BCAS3 domain-containing protein. (913 aa)
PRKAA1Non-specific serine/threonine protein kinase. (501 aa)
C5orf51Chromosome 5 open reading frame 51. (294 aa)
VPS37AVPS37A subunit of ESCRT-I. (396 aa)
RGS19Regulator of G protein signaling 19. (217 aa)
TRIM17Tripartite motif containing 17. (288 aa)
ENSCSAP00000012530Spatacsin_C domain-containing protein. (308 aa)
CHMP3Charged multivesicular body protein 3. (292 aa)
CHMP7Charged multivesicular body protein 7. (453 aa)
VAMP8Vesicle associated membrane protein 8. (100 aa)
TBC1D14TBC1 domain family member 14. (693 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
TM9SF1Transmembrane 9 superfamily member; Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. (606 aa)
CHMP4ACharged multivesicular body protein 4A. (222 aa)
CLUClusterin; Belongs to the clusterin family. (501 aa)
EVA1AEva-1 homolog A, regulator of programmed cell death. (152 aa)
SEC16AProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (2365 aa)
AUP1AUP1 lipid droplet regulating VLDL assembly factor. (410 aa)
ENSCSAP00000011477Uncharacterized protein. (207 aa)
WDR41WD repeat domain 41. (459 aa)
ARSBArylsulfatase B. (534 aa)
VPS41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa)
YOD1YOD1 deubiquitinase. (303 aa)
SLC25A46Solute carrier family 25 member 46; Belongs to the mitochondrial carrier (TC 2.A.29) family. (418 aa)
ATG10Autophagy related 10. (228 aa)
ATG12Ubiquitin-like protein ATG12; Ubiquitin-like protein involved in autophagic vesicle formation; Belongs to the ATG12 family. (140 aa)
RAB1AUncharacterized protein. (144 aa)
ABL1Tyrosine-protein kinase. (1130 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
RB1CC1RB1 inducible coiled-coil 1. (1594 aa)
ATG14Autophagy related 14. (492 aa)
FBXL4F-box and leucine rich repeat protein 4. (621 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1634 aa)
UBXN2BUBX domain protein 2B. (331 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (953 aa)
UFL1UFM1 specific ligase 1. (793 aa)
ULK3Unc-51 like kinase 3; Belongs to the protein kinase superfamily. (472 aa)
LIX1Limb and CNS expressed 1. (282 aa)
PJVKPejvakin. (352 aa)
ARL8AADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa)
TEX264Testis expressed 264, ER-phagy receptor. (315 aa)
WDR81WD repeat domain 81. (1939 aa)
LRSAM1Leucine rich repeat and sterile alpha motif containing 1. (723 aa)
SRCTyrosine-protein kinase. (633 aa)
RAB23RAB23, member RAS oncogene family. (237 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa)
DDRGK1DDRGK domain containing 1. (312 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
SNAP29Synaptosome associated protein 29. (258 aa)
TBC1D25TBC1 domain family member 25. (477 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
HDAC6Histone deacetylase 6. (1215 aa)
OPTNOptineurin. (577 aa)
ZFYVE26Zinc finger FYVE-type containing 26. (2539 aa)
USP13Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa)
STING1Transmembrane protein 173. (379 aa)
WDR45Uncharacterized protein. (360 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (443 aa)
PSEN1Presenilin 1. (467 aa)
ENSCSAP00000008892Uncharacterized protein. (190 aa)
STAMSignal transducing adaptor molecule. (540 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (165 aa)
PIP4K2APhosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa)
HERC1HECT and RLD domain containing E3 ubiquitin protein ligase family member 1. (4846 aa)
SNX30Sorting nexin family member 30. (393 aa)
STUB1STIP1 homology and U-box containing protein 1. (303 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa)
PRKNParkin RBR E3 ubiquitin protein ligase. (288 aa)
WDR24WD repeat domain 24. (790 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
MAP1LC3AMicrotubule associated protein 1 light chain 3 alpha. (121 aa)
SEC16BProtein transport protein sec16; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. (1061 aa)
TP53INP2Tumor protein p53 inducible nuclear protein 2. (220 aa)
PHF23PHD finger protein 23. (403 aa)
GABARAPGABA type A receptor-associated protein. (117 aa)
ACBD5Acyl-CoA binding domain containing 5. (535 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
TFEBTranscription factor EB. (475 aa)
OGTO-linked N-acetylglucosamine (GlcNAc) transferase. (1046 aa)
TIGARTP53 induced glycolysis regulatory phosphatase. (270 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
STX17Syntaxin 17; Belongs to the syntaxin family. (302 aa)
ARL8BADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (239 aa)
MTMR14Myotubularin related protein 14. (650 aa)
NSFL1CNSFL1 cofactor. (370 aa)
UBA5Ubiquitin like modifier activating enzyme 5. (404 aa)
ATG2BAutophagy related 2B. (2078 aa)
UBXN6UBX domain protein 6. (441 aa)
PIK3R4Phosphoinositide-3-kinase regulatory subunit 4. (1358 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
WDFY4WDFY family member 4. (2440 aa)
TECPR2Tectonin beta-propeller repeat containing 2. (1411 aa)
PHB2Prohibitin. (288 aa)
CHMP5Charged multivesicular body protein 5. (219 aa)
TOLLIPToll interacting protein. (274 aa)
XBP1X-box binding protein 1. (261 aa)
TBC1D5TBC1 domain family member 5. (797 aa)
ATG7Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (703 aa)
ILRUNInflammation and lipid regulator with UBA-like and NBR1-like domains. (298 aa)
C9orf72C9orf72-SMCR8 complex subunit. (481 aa)
GPR137BG protein-coupled receptor 137B. (384 aa)
LGALS8Galectin. (317 aa)
PLAAPhospholipase A2 activating protein. (795 aa)
MTMR3Myotubularin related protein 3. (1207 aa)
PACS2Phosphofurin acidic cluster sorting protein 2. (879 aa)
ENSCSAP00000005633Uncharacterized protein. (148 aa)
MAP1LC3CMicrotubule associated protein 1 light chain 3 gamma. (147 aa)
GABARAPL1GABA type A receptor associated protein like 1. (117 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
RUFY4RUN and FYVE domain containing 4. (571 aa)
RAB24RAB24, member RAS oncogene family. (203 aa)
ATG4ACysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (399 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (830 aa)
RNF185Ring finger protein 185. (192 aa)
RAB43RAB43, member RAS oncogene family. (212 aa)
MCOLN1Mucolipin 1. (580 aa)
ANXA7Annexin. (466 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
VPS39VPS39 subunit of HOPS complex. (751 aa)
RUBCNRubicon autophagy regulator. (1011 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (231 aa)
CLEC16AC-type lectin domain containing 16A. (1035 aa)
SQSTM1Sequestosome 1. (440 aa)
UBXN2AUBX domain protein 2A. (260 aa)
FBXO7F-box protein 7. (522 aa)
RAB19RAB19, member RAS oncogene family. (217 aa)
RETREG2Reticulophagy regulator family member 2. (543 aa)
ATG9AAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (839 aa)
HMOX1Heme oxygenase 1. (288 aa)
RAB1BRAB1B, member RAS oncogene family. (224 aa)
SMCR8SMCR8-C9orf72 complex subunit. (936 aa)
ZKSCAN3Zinc finger with KRAB and SCAN domains 3. (538 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1036 aa)
VPS13AVacuolar protein sorting 13 homolog A. (3067 aa)
VPS51VPS51 subunit of GARP complex. (806 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (973 aa)
NRBF2Nuclear receptor binding factor 2. (285 aa)
ATG2AAutophagy related 2A. (1932 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
GPR137G protein-coupled receptor 137. (396 aa)
ATG4DCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (474 aa)
TMEM39ATransmembrane protein 39A. (488 aa)
MARK2Non-specific serine/threonine protein kinase. (733 aa)
ATG9BAutophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family. (922 aa)
ATG3Autophagy-related protein 3. (314 aa)
FUNDC2FUN14 domain containing 2. (189 aa)
RAB39BRAB39B, member RAS oncogene family. (213 aa)
ATG16L1Autophagy related 16 like 1. (588 aa)
CLN3Battenin. (438 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
TMBIM6Transmembrane BAX inhibitor motif containing 6; Belongs to the BI1 family. (237 aa)
BCAS3BCAS3 domain-containing protein. (665 aa)
CHMP2BCharged multivesicular body protein 2B. (213 aa)
VMP1Vacuole membrane protein 1. (406 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1495 aa)
ATG101Autophagy related 101. (218 aa)
RAB8ARAB8A, member RAS oncogene family. (207 aa)
ATG4BCysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa)
ATG13Autophagy-related protein 13; Belongs to the ATG13 family. Metazoan subfamily. (550 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1208 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
MAP1SMicrotubule associated protein 1S. (1063 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1036 aa)
RNF41Ring finger protein 41. (317 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (224 aa)
TSG101Tumor susceptibility 101. (390 aa)
HDAC10Histone deacetylase 10. (671 aa)
SPATA18Spermatogenesis associated 18. (538 aa)
C19orf12Chromosome 19 open reading frame 12. (141 aa)
ENSCSAP00000001172Uncharacterized protein. (864 aa)
ARSAArylsulfatase A. (507 aa)
BAG3BCL2 associated athanogene 3. (575 aa)
STBD1Starch binding domain 1. (358 aa)
GRAMD1AGRAM domain containing 1A. (773 aa)
SBF2SET binding factor 2. (1881 aa)
TMEM41BTransmembrane protein 41B. (291 aa)
BNIP3BCL2 interacting protein 3. (194 aa)
WDFY3WD repeat and FYVE domain containing 3. (3547 aa)
ARFIP2ADP ribosylation factor interacting protein 2. (341 aa)
TRIM5Uncharacterized protein. (515 aa)
WIPI1WD repeat domain, phosphoinositide interacting 1. (446 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
ATG16L2Autophagy related 16 like 2. (621 aa)
CISD2CDGSH iron sulfur domain 2. (135 aa)
UVRAGUV radiation resistance associated. (699 aa)
TMEM208Transmembrane protein 208. (173 aa)
SYNPO2Synaptopodin 2. (1245 aa)
PLEKHM1Pleckstrin homology and RUN domain containing M1. (1055 aa)
GABARAPL2GABA type A receptor associated protein like 2. (117 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (24%) [HD]