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ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (703 aa) | ||||
MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (121 aa) | ||||
MAP1LC3B | Uncharacterized protein. (125 aa) | ||||
GABARAPL2 | GABA type A receptor associated protein like 2. (117 aa) | ||||
MAP1LC3C | Microtubule associated protein 1 light chain 3 gamma. (147 aa) | ||||
ENSCSAP00000005633 | Uncharacterized protein. (148 aa) |