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| | ALS2 | VPS9 domain-containing protein. (881 aa) |
| | PLEKHM1 | Pleckstrin homology and RUN domain containing M1. (1055 aa) |
| | CACNG5 | Calcium voltage-gated channel auxiliary subunit gamma 5. (278 aa) |
| | VPS4A | Uncharacterized protein; Belongs to the AAA ATPase family. (437 aa) |
| | CACNG4 | Voltage-dependent calcium channel gamma-4 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs), including GRIA1 and GRIA4. Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (327 aa) |
| | FAM160A2 | Family with sequence similarity 160 member A2. (934 aa) |
| | SCARB2 | Scavenger receptor class B member 2; Belongs to the CD36 family. (478 aa) |
| | GGA3 | Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (723 aa) |
| | LRP1 | LDL receptor related protein 1. (4544 aa) |
| | RNF157 | Ring finger protein 157. (654 aa) |
| | TSG101 | Tumor susceptibility 101. (390 aa) |
| | UEVLD | UEV and lactate/malate dehyrogenase domains. (461 aa) |
| | AKTIP | AKT interacting protein. (292 aa) |
| | VPS35 | Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa) |
| | MVB12A | Multivesicular body subunit 12A. (273 aa) |
| | USE1 | Unconventional SNARE in the ER 1. (259 aa) |
| | CHMP2B | Charged multivesicular body protein 2B. (213 aa) |
| | CLN3 | Battenin. (438 aa) |
| | VAMP7 | Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (220 aa) |
| | HOOK2 | Hook microtubule tethering protein 2. (717 aa) |
| | MTM1 | Myotubularin 1. (548 aa) |
| | DTX3L | Deltex E3 ubiquitin ligase 3L. (739 aa) |
| | CCDC91 | Coiled-coil domain containing 91. (440 aa) |
| | VPS18 | VPS18 core subunit of CORVET and HOPS complexes. (973 aa) |
| | VPS51 | VPS51 subunit of GARP complex. (806 aa) |
| | KIF13A | Kinesin family member 13A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1799 aa) |
| | CACNG2 | Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa) |
| | SPTBN5 | Spectrin beta, non-erythrocytic 5. (3671 aa) |
| | HMGXB4 | HMG-box containing 4. (601 aa) |
| | CLEC16A | C-type lectin domain containing 16A. (1035 aa) |
| | VPS39 | VPS39 subunit of HOPS complex. (751 aa) |
| | RAB7A | RAB7A, member RAS oncogene family. (207 aa) |
| | NAGPA | N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (515 aa) |
| | MGRN1 | Mahogunin ring finger 1. (576 aa) |
| | RBSN | Rabenosyn, RAB effector. (785 aa) |
| | TPCN2 | Two pore segment channel 2. (752 aa) |
| | M6PR | Mannose-6-phosphate receptor, cation dependent. (278 aa) |
| | VPS52 | VPS52 subunit of GARP complex. (723 aa) |
| | DENND3 | DENN domain containing 3. (1164 aa) |
| | LYST | Lysosomal trafficking regulator. (3804 aa) |
| | C9orf72 | C9orf72-SMCR8 complex subunit. (481 aa) |
| | CHMP5 | Charged multivesicular body protein 5. (219 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) |
| | STX8 | Syntaxin 8. (138 aa) |
| | NCOA4 | Nuclear receptor coactivator 4. (615 aa) |
| | UBXN6 | UBX domain protein 6. (441 aa) |
| | ENSCSAP00000006780 | Uncharacterized protein. (812 aa) |
| | ARL8B | ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (239 aa) |
| | EHD3 | EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa) |
| | ENSCSAP00000007559 | Uncharacterized protein. (366 aa) |
| | GNPTG | N-acetylglucosamine-1-phosphate transferase subunit gamma. (333 aa) |
| | VIPAS39 | VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog. (493 aa) |
| | NEDD4 | E3 ubiquitin-protein ligase. (900 aa) |
| | AP3D1 | AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1219 aa) |
| | CHMP4B | Charged multivesicular body protein 4B. (224 aa) |
| | PRKN | Parkin RBR E3 ubiquitin protein ligase. (288 aa) |
| | IGF2R | Insulin like growth factor 2 receptor. (2491 aa) |
| | ANKFY1 | Ankyrin repeat and FYVE domain containing 1. (1169 aa) |
| | SNX16 | Sorting nexin 16. (344 aa) |
| | CHMP4C | Charged multivesicular body protein 4C. (233 aa) |
| | TMEM106B | Transmembrane protein 106B. (274 aa) |
| | VPS16 | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa) |
| | LHCGR | Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (701 aa) |
| | RILP | Rab interacting lysosomal protein. (395 aa) |
| | ARL8A | ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa) |
| | VPS53 | VPS53 subunit of GARP complex. (832 aa) |
| | ATG14 | Autophagy related 14. (492 aa) |
| | VPS54 | VPS54 subunit of GARP complex. (965 aa) |
| | RAB7B | RAB7B, member RAS oncogene family. (199 aa) |
| | HGSNAT | Heparan-alpha-glucosaminide N-acetyltransferase. (663 aa) |
| | HOOK3 | Hook microtubule tethering protein 3. (698 aa) |
| | ZFYVE16 | Zinc finger FYVE-type containing 16. (1540 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | ARSB | Arylsulfatase B. (534 aa) |
| | AP3B1 | AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa) |
| | GAK | Cyclin G associated kinase. (1311 aa) |
| | CLU | Clusterin; Belongs to the clusterin family. (501 aa) |
| | CHMP4A | Charged multivesicular body protein 4A. (222 aa) |
| | CHMP7 | Charged multivesicular body protein 7. (453 aa) |
| | CHMP3 | Charged multivesicular body protein 3. (292 aa) |
| | TRAK1 | Trafficking kinesin protein 1. (917 aa) |
| | BIN1 | Bridging integrator 1. (608 aa) |
| | GCC2 | GRIP and coiled-coil domain containing 2. (1685 aa) |
| | TGFBRAP1 | Transforming growth factor beta receptor associated protein 1. (860 aa) |
| | LAMP1 | Lysosomal associated membrane protein 1. (416 aa) |
| | RAB12 | RAB12, member RAS oncogene family. (346 aa) |
| | NPC1 | NPC intracellular cholesterol transporter 1. (1278 aa) |
| | AP4M1 | AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (453 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | EPG5 | Ectopic P-granules autophagy protein 5 homolog. (2579 aa) |
| | CDX2 | Caudal type homeobox 2. (313 aa) |
| | LAMP2 | Lysosomal associated membrane protein 2. (410 aa) |
| | GRN | Granulin precursor. (605 aa) |
| | SCYL2 | Uncharacterized protein. (609 aa) |
| | GNPTAB | N-acetylglucosamine-1-phosphate transferase subunits alpha and beta. (1256 aa) |
| | CHMP1A | Charged multivesicular body protein 1A. (196 aa) |
| | VPS11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa) |
| | SORL1 | Sortilin related receptor 1. (2214 aa) |
| | CHMP6 | Charged multivesicular body protein 6. (201 aa) |
| | HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa) |
| | VPS33A | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (534 aa) |
| | RILPL1 | Rab interacting lysosomal protein like 1. (385 aa) |
| | CACNG7 | Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (275 aa) |
| | CACNG8 | Voltage-dependent calcium channel gamma-8 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (421 aa) |
| | SNAPIN | SNARE-associated protein Snapin; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling; Belongs to t [...] (136 aa) |
| | SNX27 | Sorting nexin 27. (528 aa) |
| | CHMP2A | Charged multivesicular body protein 2A. (222 aa) |
| | SORT1 | Sortilin. (831 aa) |
| | HOOK1 | Hook microtubule tethering protein 1. (733 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9. (692 aa) |
| | PINK1 | PTEN induced kinase 1. (581 aa) |
| | ATP13A2 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1175 aa) |
| | RHOB | Ras homolog family member B. (196 aa) |
| | PLEKHF1 | Pleckstrin homology and FYVE domain containing 1. (279 aa) |
| | PLEKHF2 | Pleckstrin homology and FYVE domain containing 2. (249 aa) |
