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| | ENSCSAP00000003769 | Uncharacterized protein. (473 aa) |
| | TMPRSS6 | Transmembrane serine protease 6; Belongs to the peptidase S1 family. (800 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (799 aa) |
| | LTBP3 | Latent transforming growth factor beta binding protein 3. (1298 aa) |
| | HFE | Homeostatic iron regulator; Belongs to the MHC class I family. (300 aa) |
| | FAM83G | Family with sequence similarity 83 member G. (673 aa) |
| | INHA | Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa) |
| | GDF7 | Growth differentiation factor 7. (447 aa) |
| | TGFBR3L | Transforming growth factor beta receptor 3 like. (314 aa) |
| | NODAL | Nodal growth differentiation factor. (347 aa) |
| | FOXH1 | Forkhead box H1. (365 aa) |
| | ENSCSAP00000004608 | RRM domain-containing protein. (147 aa) |
| | HIPK2 | Homeodomain interacting protein kinase 2. (1198 aa) |
| | FLCN | Folliculin. (579 aa) |
| | NRROS | Negative regulator of reactive oxygen species. (732 aa) |
| | SCX | Scleraxis bHLH transcription factor. (201 aa) |
| | CHRDL1 | Chordin like 1. (458 aa) |
| | ZMIZ1 | Zinc finger MIZ-type containing 1. (1067 aa) |
| | PTK2 | Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1038 aa) |
| | TGFBR2 | TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa) |
| | BMPR1A | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa) |
| | GDF3 | Growth differentiation factor 3. (364 aa) |
| | ITGB8 | Integrin beta; Belongs to the integrin beta chain family. (769 aa) |
| | ZCCHC12 | Zinc finger CCHC-type containing 12. (404 aa) |
| | CLDN5 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa) |
| | EID2 | EP300 interacting inhibitor of differentiation 2. (236 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | CITED2 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa) |
| | TMEM100 | Transmembrane protein 100. (134 aa) |
| | NOG | Noggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa) |
| | SKI | SKI proto-oncogene. (728 aa) |
| | HES5 | Hes family bHLH transcription factor 5. (166 aa) |
| | ENSCSAP00000016885 | TGFb_propeptide domain-containing protein. (144 aa) |
| | ENSCSAP00000016884 | TGF_BETA_2 domain-containing protein. (292 aa) |
| | ENSCSAP00000016878 | TGF_BETA_2 domain-containing protein. (354 aa) |
| | ZFYVE9 | Zinc finger FYVE domain-containing protein. (1380 aa) |
| | TGFBR3 | Transforming growth factor beta receptor 3. (860 aa) |
| | ZNF8 | Zinc finger protein 8. (575 aa) |
| | NOTCH2 | Notch receptor 2. (2471 aa) |
| | HJV | Hemojuvelin BMP co-receptor. (425 aa) |
| | HNF1A | HNF1 homeobox A. (632 aa) |
| | PXN | Paxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (591 aa) |
| | BTBD11 | BTB domain containing 11. (599 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (664 aa) |
| | CHST11 | Carbohydrate sulfotransferase. (352 aa) |
| | HPGD | 15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | SMAD1 | Mothers against decapentaplegic homolog. (465 aa) |
| | MEGF8 | Multiple EGF like domains 8. (2789 aa) |
| | SOST | Sclerostin. (213 aa) |
| | TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa) |
| | USP9Y | Ubiquitin specific peptidase 9 Y-linked; Belongs to the peptidase C19 family. (2237 aa) |
| | ONECUT2 | One cut domain family member. (504 aa) |
| | SMAD4 | Mothers against decapentaplegic homolog. (552 aa) |
| | FGF9 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | SMAD2 | Mothers against decapentaplegic homolog. (467 aa) |
| | SPART | Spartin. (666 aa) |
| | SMAD9 | Mothers against decapentaplegic homolog. (467 aa) |
| | DSG4 | Desmoglein 4; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1052 aa) |
| | SMURF1 | E3 ubiquitin-protein ligase. (728 aa) |
| | CFC1 | EGF-like domain-containing protein. (227 aa) |
| | TWSG1 | Twisted gastrulation BMP signaling modulator 1. (223 aa) |
| | TGFBRAP1 | Transforming growth factor beta receptor associated protein 1. (860 aa) |
| | FURIN | Furin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa) |
| | RGMA | Repulsive guidance molecule BMP co-receptor a. (450 aa) |
| | INHBB | Inhibin subunit beta B. (320 aa) |
| | FST | Follistatin. (344 aa) |
| | PTPRK | Protein tyrosine phosphatase receptor type K. (1461 aa) |
| | PARP1 | Poly(ADP-ribose) polymerase 1. (709 aa) |
| | LEFTY2 | Left-right determination factor. (366 aa) |
| | LEFTY1 | Left-right determination factor. (366 aa) |
| | MSX1 | Msh homeobox 1. (303 aa) |
| | ATOH8 | Atonal bHLH transcription factor 8. (330 aa) |
| | TDGF1 | Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (187 aa) |
| | ACVR2A | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa) |
| | ACVR1C | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (443 aa) |
| | ACVR1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa) |
| | ITGB6 | Integrin beta; Belongs to the integrin beta chain family. (788 aa) |
| | CCDC142 | Coiled-coil domain containing 142. (750 aa) |
| | ZNF831 | Zinc finger protein 831. (1676 aa) |
| | BMP7 | Bone morphogenetic protein 7. (431 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (819 aa) |
| | RGMB | Repulsive guidance molecule BMP co-receptor b. (478 aa) |
| | INHBA | Inhibin subunit beta A. (426 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | FERMT2 | Fermitin family member 2. (507 aa) |
| | BMP10 | Bone morphogenetic protein 10. (424 aa) |
| | FNTA | Farnesyltransferase, CAAX box, alpha. (453 aa) |
| | BMPER | BMP binding endothelial regulator. (685 aa) |
| | BMP4 | Bone morphogenetic protein 4. (408 aa) |
| | ABL1 | Tyrosine-protein kinase. (1130 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa) |
| | ACVR2B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa) |
| | FMOD | Fibromodulin. (376 aa) |
| | LNPEP | Leucyl and cystinyl aminopeptidase. (1025 aa) |
| | HNF4A | Hepatocyte nuclear factor 4 alpha. (474 aa) |
| | PML | Promyelocytic leukemia. (819 aa) |
| | USP9X | Ubiquitin specific peptidase 9 X-linked; Belongs to the peptidase C19 family. (2554 aa) |
| | SPTBN1 | Spectrin beta chain; Belongs to the spectrin family. (2364 aa) |
| | ENG | Endoglin. (658 aa) |
| | HEXA | Beta-hexosaminidase. (529 aa) |
| | CHRD | Chordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (956 aa) |
| | SRC | Tyrosine-protein kinase. (633 aa) |
| | JADE2 | Jade family PHD finger 2. (834 aa) |
| | BMP2 | Bone morphogenetic protein 2. (396 aa) |
| | SOSTDC1 | Sclerostin domain containing 1. (206 aa) |
| | FUT8 | Alpha-(1,6)-fucosyltransferase; Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans. Belongs to the glycosyltransferase 23 family. (575 aa) |
| | SMAD5 | Mothers against decapentaplegic homolog. (465 aa) |
| | SMAD3 | Mothers against decapentaplegic homolog. (425 aa) |
| | BMP5 | Bone morphogenetic protein 5. (454 aa) |
| | SMAD6 | Mothers against decapentaplegic homolog. (496 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (542 aa) |
| | DLX5 | Distal-less homeobox 5. (289 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | ITGA8 | Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1063 aa) |
| | NCEH1 | Neutral cholesterol ester hydrolase 1. (408 aa) |
| | COL1A2 | Collagen type I alpha 2 chain. (1274 aa) |
| | APPL1 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1. (709 aa) |
| | ID1 | Inhibitor of DNA binding 1, HLH protein. (154 aa) |
| | AKAP4 | A-kinase anchoring protein 4. (854 aa) |
| | BMP15 | Bone morphogenetic protein 15. (393 aa) |
| | VIM | Vimentin; Belongs to the intermediate filament family. (466 aa) |
| | SKIL | SKI like proto-oncogene. (684 aa) |
| | RUNX2 | Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (450 aa) |
| | GDF6 | Growth differentiation factor 6. (455 aa) |
| | COL3A1 | Collagen type III alpha 1 chain. (878 aa) |
| | PPM1L | Protein phosphatase, Mg2+/Mn2+ dependent 1L. (250 aa) |
| | LTBP2 | Latent transforming growth factor beta binding protein 2. (1824 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1. (303 aa) |
| | MSTN | Myostatin. (375 aa) |
| | TBXT | T-box transcription factor T. (436 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | RNF111 | Ring finger protein 111. (985 aa) |
| | SLC33A1 | Solute carrier family 33 member 1. (550 aa) |
| | TGFB3 | Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa) |
| | ENSCSAP00000008056 | Uncharacterized protein. (534 aa) |
| | BAMBI | BMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (260 aa) |
| | AMH | Anti-Mullerian hormone. (566 aa) |
| | LTBP1 | Latent transforming growth factor beta binding protein 1. (1724 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | CITED1 | Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 1. (219 aa) |
| | TGFBR1 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa) |
| | AKAP3 | A-kinase anchoring protein 3. (857 aa) |
| | EXT1 | Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (420 aa) |
| | TF | Transferrin; Belongs to the transferrin family. (698 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | GDF5 | Growth differentiation factor 5. (499 aa) |
| | MAPK14 | Mitogen-activated protein kinase. (360 aa) |
| | GDF10 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa) |
| | TGIF2 | TGFB induced factor homeobox 2. (237 aa) |
| | GDF2 | Growth differentiation factor 2. (429 aa) |
| | ETV2 | ETS variant 2. (375 aa) |
| | BMP3 | Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa) |
| | GLG1 | Golgi glycoprotein 1. (1051 aa) |
| | USP15 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (981 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (785 aa) |
| | AFP | Alpha fetoprotein. (609 aa) |
| | INHBE | Inhibin subunit beta E. (351 aa) |
| | INHBC | Inhibin subunit beta C. (352 aa) |
| | NUP93 | Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (819 aa) |
| | PDCD4 | Programmed cell death 4. (469 aa) |
| | SLC39A5 | Solute carrier family 39 member 5. (540 aa) |
| | DLX3 | Distal-less homeobox 3. (287 aa) |
| | COMP | Cartilage oligomeric matrix protein. (757 aa) |
| | GDF11 | Growth differentiation factor 11. (406 aa) |
| | FKBP8 | Peptidylprolyl isomerase. (413 aa) |
| | AMHR2 | Anti-Muellerian hormone type-2 receptor; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone. (573 aa) |
| | WFIKKN2 | WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa) |
| | MTMR4 | Myotubularin related protein 4. (1195 aa) |
| | ACVR1B | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (453 aa) |
| | ACVRL1 | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa) |
| | LPXN | Leupaxin; Transcriptional coactivator for androgen receptor (AR) and serum response factor (SRF). Contributes to the regulation of cell adhesion, spreading and cell migration and acts as a negative regulator in integrin-mediated cell adhesion events. Suppresses the integrin- induced tyrosine phosphorylation of paxillin (PXN). (386 aa) |
| | MAPK3 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | DUSP22 | Dual specificity phosphatase 22; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (184 aa) |
| | ZYX | Zyxin. (419 aa) |
| | NLK | Mitogen-activated protein kinase. (376 aa) |
| | BMP6 | Bone morphogenetic protein 6. (433 aa) |
| | GCNT2 | Glucosaminyl (N-acetyl) transferase 2 (I blood group). (402 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | HIVEP1 | Uncharacterized protein. (2175 aa) |
| | LTBP4 | Latent transforming growth factor beta binding protein 4. (1557 aa) |
| | LRRC32 | Leucine rich repeat containing 32. (662 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (331 aa) |
| | DDX5 | DEAD-box helicase 5; Belongs to the DEAD box helicase family. (614 aa) |
| | SMURF2 | SMAD specific E3 ubiquitin protein ligase 2. (474 aa) |
| | SMPD3 | Sphingomyelin phosphodiesterase 3. (655 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa) |
