STRINGSTRING
MMP15 MMP15 DUSP5 DUSP5 MMP2 MMP2 ITGA7 ITGA7 ITGA5 ITGA5 HOXC11 HOXC11 LDB1 LDB1 FGF8 FGF8 COL8A1 COL8A1 HNF1B HNF1B DKK1 DKK1 COL6A1 COL6A1 ITGB2 ITGB2 RTF1 RTF1 ITGB5 ITGB5 NODAL NODAL FN1 FN1 DUSP1 DUSP1 EOMES EOMES BMPR1A BMPR1A GDF3 GDF3 EXT1 EXT1 LAMB1 LAMB1 LEO1 LEO1 MED12 MED12 KIF16B KIF16B ITGAV ITGAV LAMC1 LAMC1 ITGA4 ITGA4 ZFP36L1 ZFP36L1 WNT8A WNT8A SMAD3 SMAD3 ENSCSAP00000009499 ENSCSAP00000009499 CDC73 CDC73 NR0B1 NR0B1 SOX17 SOX17 MMP9 MMP9 BMP4 BMP4 TBX20 TBX20 LAMB3 LAMB3 INHBA INHBA NKX2-1 NKX2-1 COL7A1 COL7A1 DUSP4 DUSP4 NOTCH1 NOTCH1 SETD2 SETD2 MMP14 MMP14 MIXL1 MIXL1 EPB41L5 EPB41L5 PELO PELO CTNNB1 CTNNB1 SOX7 SOX7 GATA4 GATA4 DUSP2 DUSP2 COL4A2 COL4A2 GATA6 GATA6 LAMA3 LAMA3 SMAD2 SMAD2 SMAD4 SMAD4 TGFB1 TGFB1 MMP8 MMP8 ENSCSAP00000016053 ENSCSAP00000016053 COL11A1 COL11A1 ENSCSAP00000016711 ENSCSAP00000016711 HDAC1 HDAC1 NOG NOG ARC ARC ENSCSAP00000017750 ENSCSAP00000017750 PAF1 PAF1 BPTF BPTF ENSCSAP00000000740 ENSCSAP00000000740 CTR9 CTR9 GRB2 GRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MMP15Matrix metallopeptidase 15. (669 aa)
DUSP5Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (384 aa)
MMP2Matrix metallopeptidase 2. (661 aa)
ITGA7Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (828 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
HOXC11Homeobox C11. (304 aa)
LDB1LIM domain binding 1. (411 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
COL8A1Collagen type VIII alpha 1 chain. (746 aa)
HNF1BHNF1 homeobox B. (557 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
COL6A1Uncharacterized protein. (1003 aa)
ITGB2Integrin beta. (784 aa)
RTF1RTF1 homolog, Paf1/RNA polymerase II complex component. (670 aa)
ITGB5Integrin beta; Belongs to the integrin beta chain family. (799 aa)
NODALNodal growth differentiation factor. (347 aa)
FN1Fibronectin 1. (2265 aa)
DUSP1Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (367 aa)
EOMESEomesodermin. (419 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
GDF3Growth differentiation factor 3. (364 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (420 aa)
LAMB1Laminin subunit beta 1. (1786 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (666 aa)
MED12Mediator complex subunit 12. (2090 aa)
KIF16BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1328 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
LAMC1Laminin subunit gamma 1. (1573 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa)
ZFP36L1ZFP36 ring finger protein like 1. (338 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
ENSCSAP00000009499Uncharacterized protein. (288 aa)
CDC73Cell division cycle 73. (531 aa)
NR0B1Nuclear receptor subfamily 0 group B member 1. (470 aa)
SOX17SRY-box transcription factor 17. (412 aa)
MMP9Matrix metallopeptidase 9. (707 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
TBX20T-box transcription factor 20. (447 aa)
LAMB3Laminin subunit beta 3. (1172 aa)
INHBAInhibin subunit beta A. (426 aa)
NKX2-1NK2 homeobox 1. (371 aa)
COL7A1Collagen type VII alpha 1 chain. (2946 aa)
DUSP4Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (394 aa)
NOTCH1Notch receptor 1. (2555 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2565 aa)
MMP14Matrix metallopeptidase 14. (582 aa)
MIXL1Mix paired-like homeobox. (232 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (699 aa)
PELOProtein pelota homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (385 aa)
CTNNB1Catenin beta 1. (781 aa)
SOX7SRY-box transcription factor 7. (340 aa)
GATA4GATA binding protein 4. (442 aa)
DUSP2Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (315 aa)
COL4A2Collagen type IV alpha 2 chain. (1696 aa)
GATA6GATA binding protein 6. (595 aa)
LAMA3Laminin subunit alpha 3. (3333 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
MMP8Matrix metallopeptidase 8. (468 aa)
ENSCSAP00000016053Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (497 aa)
COL11A1Collagen type XI alpha 1 chain. (1806 aa)
ENSCSAP00000016711Uncharacterized protein. (296 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ARCActivity regulated cytoskeleton associated protein. (396 aa)
ENSCSAP00000017750Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (479 aa)
PAF1PAF1 homolog, Paf1/RNA polymerase II complex component. (531 aa)
BPTFBromodomain PHD finger transcription factor. (2875 aa)
ENSCSAP00000000740Uncharacterized protein. (88 aa)
CTR9CTR9 homolog, Paf1/RNA polymerase II complex component. (1173 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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