STRINGSTRING
COL3A1 COL3A1 TFPI TFPI ENPP4 ENPP4 TFPI2 TFPI2 DGKK DGKK PIK3CA PIK3CA GP1BA GP1BA GATA1 GATA1 WAS WAS SERPIND1 SERPIND1 DGKB DGKB P2RX1 P2RX1 F13B F13B ENSCSAP00000009778 ENSCSAP00000009778 SRC SRC CSRP1 CSRP1 DGKG DGKG HNF4A HNF4A HRG HRG ENSCSAP00000010534 ENSCSAP00000010534 PLEK PLEK C4BPB C4BPB ADAMTS13 ADAMTS13 AP3B1 AP3B1 F2R F2R F2RL2 F2RL2 DGKQ DGKQ VAV2 VAV2 GNAS GNAS PPIA PPIA CTSG CTSG HGFAC HGFAC ENTPD2 ENTPD2 WNT3A WNT3A ITGA2 ITGA2 MERTK MERTK PROC PROC GAS6 GAS6 PROZ PROZ F10 F10 F7 F7 GNA12 GNA12 CPB2 CPB2 DGKH DGKH HSPB1 HSPB1 LMAN1 LMAN1 AXL AXL SLC7A11 SLC7A11 SLC4A1 SLC4A1 PLCG2 PLCG2 FGB FGB FGG FGG F11 F11 ENSCSAP00000015436 ENSCSAP00000015436 UBASH3B UBASH3B PEAR1 PEAR1 ENSCSAP00000016261 ENSCSAP00000016261 STXBP3 STXBP3 VAV3 VAV3 F3 F3 MPL MPL PABPC4 PABPC4 LCK LCK PAFAH2 PAFAH2 HPS6 HPS6 ADRA2A ADRA2A THBD THBD LOC103243499 LOC103243499 GP9 GP9 RAP2B RAP2B P2RY12 P2RY12 ADRA2B ADRA2B C1GALT1C1 C1GALT1C1 BLOC1S3 BLOC1S3 BLOC1S4 BLOC1S4 ADRA2C ADRA2C FGA FGA ANXA5 ANXA5 ITGB3 ITGB3 GNA13 GNA13 APOH APOH MMRN1 MMRN1 PF4 PF4 PF4V1 PF4V1 HPS5 HPS5 COMP COMP DGKA DGKA FBLN1 FBLN1 DGKE DGKE SCUBE1 SCUBE1 DGKZ DGKZ F2 F2 F2RL3 F2RL3 VKORC1 VKORC1 PROS1 PROS1 SERPING1 SERPING1 ENTPD1 ENTPD1 DGKD DGKD SHH SHH PRSS56 PRSS56 F8 F8 ANO6 ANO6 FLNA FLNA PAPSS2 PAPSS2 FERMT3 FERMT3 SYK SYK F13A1 F13A1 F9 F9 JMJD1C JMJD1C CD40LG CD40LG DTNBP1 DTNBP1 GNAQ GNAQ SERPINE2 SERPINE2 TYRO3 TYRO3 MYH9 MYH9 MPIG6B MPIG6B CLIC1 CLIC1 DGKI DGKI F12 F12 VCL VCL FN1 FN1 VAV1 VAV1 KNG1 KNG1 TSPAN32 TSPAN32 MYL9 MYL9 HPS4 HPS4 PTPN6 PTPN6 BLOC1S6 BLOC1S6 TLN1 TLN1 ADORA2A ADORA2A CD9 CD9 VWF VWF SERPINA10 SERPINA10 PIK3CB PIK3CB F5 F5 TREML1 TREML1 ITPK1 ITPK1 PLSCR1 PLSCR1 PIK3CG PIK3CG SRF SRF RAB27A RAB27A PROCR PROCR CD36 CD36 FZD6 FZD6 PLG PLG
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
COL3A1Collagen type III alpha 1 chain. (878 aa)
TFPITissue factor pathway inhibitor. (300 aa)
ENPP4Ectonucleotide pyrophosphatase/phosphodiesterase 4. (453 aa)
TFPI2Tissue factor pathway inhibitor. (235 aa)
DGKKDiacylglycerol kinase. (1273 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
GP1BAGlycoprotein Ib platelet subunit alpha. (628 aa)
GATA1GATA binding protein 1. (414 aa)
WASWASP actin nucleation promoting factor. (502 aa)
SERPIND1Serpin family D member 1; Belongs to the serpin family. (499 aa)
DGKBDiacylglycerol kinase. (706 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
F13BCoagulation factor XIII B chain. (651 aa)
ENSCSAP00000009778Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (165 aa)
SRCTyrosine-protein kinase. (633 aa)
CSRP1Cysteine and glycine rich protein 1. (193 aa)
DGKGDiacylglycerol kinase. (791 aa)
HNF4AHepatocyte nuclear factor 4 alpha. (474 aa)
HRGHistidine rich glycoprotein. (521 aa)
ENSCSAP00000010534Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
PLEKPleckstrin. (350 aa)
C4BPBComplement component 4 binding protein beta. (252 aa)
ADAMTS13ADAM metallopeptidase with thrombospondin type 1 motif 13. (1425 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
F2RL2Coagulation factor II thrombin receptor like 2; Belongs to the G-protein coupled receptor 1 family. (374 aa)
DGKQDiacylglycerol kinase. (941 aa)
VAV2Vav guanine nucleotide exchange factor 2. (896 aa)
GNASUncharacterized protein. (335 aa)
PPIAPeptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (166 aa)
CTSGCathepsin G; Belongs to the peptidase S1 family. (255 aa)
HGFACHGF activator. (538 aa)
ENTPD2Ectonucleoside triphosphate diphosphohydrolase 2; Belongs to the GDA1/CD39 NTPase family. (495 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
MERTKMER proto-oncogene, tyrosine kinase. (995 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa; Belongs to the peptidase S1 family. (547 aa)
GAS6Growth arrest specific 6. (542 aa)
PROZProtein Z, vitamin K dependent plasma glycoprotein; Belongs to the peptidase S1 family. (421 aa)
F10Coagulation factor X. (488 aa)
F7Coagulation factor VII. (526 aa)
GNA12G protein subunit alpha 12. (305 aa)
CPB2Carboxypeptidase B2. (423 aa)
DGKHDiacylglycerol kinase. (1220 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (143 aa)
LMAN1Lectin, mannose binding 1. (510 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
SLC7A11Solute carrier family 7 member 11. (501 aa)
SLC4A1Anion exchange protein. (924 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1265 aa)
FGBFibrinogen beta chain. (491 aa)
FGGFibrinogen gamma chain. (437 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (609 aa)
ENSCSAP00000015436Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (159 aa)
UBASH3BUbiquitin associated and SH3 domain containing B. (649 aa)
PEAR1Platelet endothelial aggregation receptor 1. (1037 aa)
ENSCSAP00000016261Uncharacterized protein. (319 aa)
STXBP3Syntaxin binding protein 3; Belongs to the STXBP/unc-18/SEC1 family. (592 aa)
VAV3Vav guanine nucleotide exchange factor 3. (782 aa)
F3Coagulation factor III, tissue factor. (245 aa)
MPLMPL proto-oncogene, thrombopoietin receptor. (635 aa)
PABPC4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (660 aa)
LCKTyrosine-protein kinase. (513 aa)
PAFAH2Platelet-activating factor acetylhydrolase. (428 aa)
HPS6Hermansky-Pudlak syndrome 6 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (775 aa)
ADRA2AAdrenoceptor alpha 2A. (450 aa)
THBDThrombomodulin. (626 aa)
LOC103243499Uncharacterized protein. (251 aa)
GP9Glycoprotein IX platelet. (177 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
P2RY12Purinergic receptor P2Y12. (342 aa)
ADRA2BAdrenoceptor alpha 2B. (447 aa)
C1GALT1C1C1GALT1 specific chaperone 1. (318 aa)
BLOC1S3Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO). Belongs to the BLOC1S3 family. (200 aa)
BLOC1S4Biogenesis of lysosomal organelles complex 1 subunit 4. (216 aa)
ADRA2CAdrenoceptor alpha 2C. (456 aa)
FGAFibrinogen alpha chain. (875 aa)
ANXA5Annexin. (320 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (741 aa)
GNA13G protein subunit alpha 13. (377 aa)
APOHApolipoprotein H. (266 aa)
MMRN1Multimerin 1. (1224 aa)
PF4Platelet factor 4. (73 aa)
PF4V1C-X-C motif chemokine. (75 aa)
HPS5Hermansky-Pudlak syndrome 5 protein homolog; May regulate the synthesis and function of lysosomes and of highly specialized organelles, such as melanosomes and platelet dense granules. (1129 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
DGKADiacylglycerol kinase. (737 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (703 aa)
DGKEDiacylglycerol kinase. (567 aa)
SCUBE1Signal peptide, CUB domain and EGF like domain containing 1. (630 aa)
DGKZDiacylglycerol kinase. (929 aa)
F2Coagulation factor II, thrombin; Belongs to the peptidase S1 family. (596 aa)
F2RL3F2R like thrombin or trypsin receptor 3; Belongs to the G-protein coupled receptor 1 family. (385 aa)
VKORC1Vitamin K epoxide reductase complex subunit 1. (163 aa)
PROS1Protein S. (676 aa)
SERPING1Serpin family G member 1; Belongs to the serpin family. (500 aa)
ENTPD1Ectonucleoside triphosphate diphosphohydrolase 1; Belongs to the GDA1/CD39 NTPase family. (571 aa)
DGKDDiacylglycerol kinase. (1156 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
PRSS56Serine protease 56; Belongs to the peptidase S1 family. (604 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2355 aa)
ANO6Anoctamin. (910 aa)
FLNAFilamin A. (2639 aa)
PAPSS23'-phosphoadenosine 5'-phosphosulfate synthase 2. (619 aa)
FERMT3Fermitin family member 3. (663 aa)
SYKTyrosine-protein kinase. (635 aa)
F13A1Coagulation factor XIII A chain. (732 aa)
F9Coagulation factor IX. (461 aa)
JMJD1CJumonji domain containing 1C. (1362 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa)
DTNBP1Dystrobrevin binding protein 1. (350 aa)
GNAQG protein subunit alpha q. (301 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (409 aa)
TYRO3TYRO3 protein tyrosine kinase. (890 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
MPIG6BMegakaryocyte and platelet inhibitory receptor G6b. (241 aa)
CLIC1Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (241 aa)
DGKIDiacylglycerol kinase. (809 aa)
F12Coagulation factor XII. (615 aa)
VCLVinculin. (1134 aa)
FN1Fibronectin 1. (2265 aa)
VAV1Vav guanine nucleotide exchange factor 1. (719 aa)
KNG1Kininogen 1. (427 aa)
TSPAN32Tetraspanin 32; Belongs to the tetraspanin (TM4SF) family. (320 aa)
MYL9Myosin light chain 9. (172 aa)
HPS4HPS4 biogenesis of lysosomal organelles complex 3 subunit 2. (705 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (595 aa)
BLOC1S6Biogenesis of lysosome-related organelles complex 1 subunit 6; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particular [...] (172 aa)
TLN1Talin 1. (2558 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
CD9Tetraspanin. (228 aa)
VWFVon Willebrand factor. (2813 aa)
SERPINA10Serpin family A member 10; Belongs to the serpin family. (472 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2156 aa)
TREML1Triggering receptor expressed on myeloid cells like 1. (311 aa)
ITPK1Inositol-tetrakisphosphate 1-kinase. (414 aa)
PLSCR1Phospholipid scramblase; May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. Belongs to the phospholipid scramblase family. (313 aa)
PIK3CGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (918 aa)
SRFSerum response factor. (508 aa)
RAB27ARAB27A, member RAS oncogene family. (221 aa)
PROCRProtein C receptor. (238 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (810 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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