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GEN1 | GEN1 Holliday junction 5' flap endonuclease. (907 aa) | ||||
ENSCSAP00000017472 | ERCC4 domain-containing protein. (551 aa) | ||||
SLX1 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products. (275 aa) | ||||
RAD51C | RAD51 paralog C. (367 aa) |