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| | IMPACT | Impact RWD domain protein. (320 aa) |
| | BRCA2 | BRCA2 DNA repair associated. (3420 aa) |
| | BCL2 | BCL2 apoptosis regulator. (239 aa) |
| | SERPINB13 | Serpin family B member 13; Belongs to the serpin family. (391 aa) |
| | CUL4B | Cullin 4B; Belongs to the cullin family. (900 aa) |
| | UBE2A | Ubiquitin conjugating enzyme E2 A; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (707 aa) |
| | BCL3 | BCL3 transcription coactivator. (358 aa) |
| | ENSCSAP00000014836 | Uncharacterized protein. (329 aa) |
| | MMP1 | Matrix metallopeptidase 1. (469 aa) |
| | MMP3 | Matrix metallopeptidase 3. (477 aa) |
| | ERCC2 | ERCC excision repair 2, TFIIH core complex helicase subunit. (736 aa) |
| | NSMCE3 | NSE3 homolog, SMC5-SMC6 complex component. (304 aa) |
| | MC1R | Melanocyte-stimulating hormone receptor; Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. (317 aa) |
| | ENSCSAP00000017976 | Uncharacterized protein. (145 aa) |
| | IVL | Involucrin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia. (469 aa) |
| | ENSCSAP00000017875 | Uncharacterized protein. (370 aa) |
| | H2AW | Histone H2A; Belongs to the histone H2A family. (130 aa) |
| | TRIM32 | Tripartite motif containing 32. (653 aa) |
| | NOC2L | NOC2 like nucleolar associated transcriptional repressor. (756 aa) |
| | UBE4B | Ubiquitination factor E4B. (1040 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (415 aa) |
| | KDM1A | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (872 aa) |
| | USP1 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (785 aa) |
| | BRSK1 | BR serine/threonine kinase 1. (703 aa) |
| | POLD1 | DNA polymerase. (1086 aa) |
| | TRIAP1 | TP53 regulated inhibitor of apoptosis 1. (76 aa) |
| | CHEK1 | Checkpoint kinase 1. (749 aa) |
| | USF1 | Upstream transcription factor 1. (366 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | USP28 | Ubiquitin specific peptidase 28; Belongs to the peptidase C19 family. (1139 aa) |
| | PRIMPOL | Primase and DNA directed polymerase. (556 aa) |
| | ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa) |
| | SDE2 | SDE2 telomere maintenance homolog. (451 aa) |
| | ENSCSAP00000003275 | Uncharacterized protein. (261 aa) |
| | CDKN2D | Cyclin dependent kinase inhibitor 2D. (166 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1649 aa) |
| | BMF | Bcl2 modifying factor. (184 aa) |
| | MEN1 | Menin 1. (610 aa) |
| | SIRT1 | Sirtuin 1. (743 aa) |
| | DCUN1D3 | DCN1-like protein. (304 aa) |
| | INO80 | INO80 complex ATPase subunit. (1556 aa) |
| | RHBDD1 | Rhomboid domain containing 1. (316 aa) |
| | MFAP4 | Microfibril associated protein 4. (255 aa) |
| | RELA | RELA proto-oncogene, NF-kB subunit. (548 aa) |
| | ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (735 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (517 aa) |
| | CCND1 | Cyclin D1; Belongs to the cyclin family. (295 aa) |
| | CRIP1 | LIM zinc-binding domain-containing protein. (77 aa) |
| | XPC | XPC complex subunit, DNA damage recognition and repair factor. (888 aa) |
| | OPN3 | Opsin 3; Belongs to the G-protein coupled receptor 1 family. (402 aa) |
| | ENSCSAP00000005812 | KOW domain-containing protein. (119 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (211 aa) |
| | CREBBP | CREB binding protein. (2417 aa) |
| | NPM1 | Nucleophosmin 1. (294 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | TAF1L | TATA-box binding protein associated factor 1 like. (1476 aa) |
| | OPN1SW | Opsin 1, short wave sensitive. (349 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (439 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (384 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (365 aa) |
| | ENSCSAP00000006521 | Uncharacterized protein. (266 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (164 aa) |
| | SPRTN | SprT-like N-terminal domain. (488 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1494 aa) |
| | RPL26 | Ribosomal protein L26. (145 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (344 aa) |
| | SIRT6 | Sirtuin 6. (355 aa) |
| | XPA | XPA, DNA damage recognition and repair factor. (226 aa) |
| | TAF1 | Transcription initiation factor TFIID subunit. (1894 aa) |
| | RHNO1 | RAD9-HUS1-RAD1 interacting nuclear orphan 1. (240 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2644 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa) |
| | ENSCSAP00000007810 | Uncharacterized protein. (88 aa) |
| | NEDD4 | E3 ubiquitin-protein ligase. (900 aa) |
| | DHX36 | DEAH-box helicase 36. (1007 aa) |
| | POLH | DNA polymerase eta. (712 aa) |
| | IL12A | Interleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (253 aa) |
| | CIRBP | Cold inducible RNA binding protein. (172 aa) |
| | MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1601 aa) |
| | STK11 | Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (433 aa) |
| | MAP4K3 | Mitogen-activated protein kinase kinase kinase kinase 3; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (894 aa) |
| | PCLAF | Uncharacterized protein. (111 aa) |
| | TP53INP1 | Tumor protein p53 inducible nuclear protein 1. (165 aa) |
| | OPN5 | Opsin 5; Belongs to the G-protein coupled receptor 1 family. (352 aa) |
| | ELANE | Elastase, neutrophil expressed; Belongs to the peptidase S1 family. (263 aa) |
| | RPAIN | RPA interacting protein. (219 aa) |
| | PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) |
| | TIPIN | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (307 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (572 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | RO60 | Ro60, Y RNA binding protein. (538 aa) |
| | MSH2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (933 aa) |
| | MSH6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1360 aa) |
| | UBE2B | Ubiquitin conjugating enzyme E2 B; Belongs to the ubiquitin-conjugating enzyme family. (152 aa) |
| | TIMP1 | TIMP metallopeptidase inhibitor 1. (207 aa) |
| | ZBTB1 | Zinc finger and BTB domain containing 1. (644 aa) |
| | ACTR5 | Actin related protein 5; Belongs to the actin family. (515 aa) |
| | PML | Promyelocytic leukemia. (819 aa) |
| | HYAL2 | Hyaluronidase. (473 aa) |
| | HYAL1 | Hyaluronidase. (450 aa) |
| | HYAL3 | Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Belongs to the glycosyl hydrolase 56 family. (417 aa) |
| | ENSCSAP00000010702 | Nucleoplasmin domain-containing protein. (275 aa) |
| | MMP9 | Matrix metallopeptidase 9. (707 aa) |
| | AQP1 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa) |
| | GPX1 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa) |
| | DTL | Denticleless E3 ubiquitin protein ligase homolog. (730 aa) |
| | POLK | DNA polymerase kappa. (847 aa) |
| | UVSSA | UV stimulated scaffold protein A. (709 aa) |
| | C9orf116 | Chromosome 9 open reading frame 116. (136 aa) |
| | WRN | WRN RecQ like helicase. (1399 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (901 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | CDC25A | Cell division cycle 25A. (523 aa) |
| | PBK | PDZ binding kinase. (322 aa) |
| | SCARA3 | Scavenger receptor class A member 3. (606 aa) |
| | ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1210 aa) |
| | TP53I13 | Tumor protein p53 inducible protein 13. (368 aa) |
| | CCAR2 | Cell cycle and apoptosis regulator 2. (920 aa) |
| | PARP1 | Poly(ADP-ribose) polymerase 1. (709 aa) |
| | ZRANB3 | Zinc finger RANBP2-type containing 3. (1016 aa) |
| | PTPRK | Protein tyrosine phosphatase receptor type K. (1461 aa) |
| | METTL3 | Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa) |
| | ERCC3 | ERCC excision repair 3, TFIIH core complex helicase subunit. (782 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (501 aa) |
| | ENSCSAP00000013063 | Uncharacterized protein. (278 aa) |
| | REV1 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1248 aa) |
| | CUL4A | Cullin 4A; Belongs to the cullin family. (759 aa) |
| | BIVM | Basic, immunoglobulin-like variable motif containing. (503 aa) |
| | POLD3 | Uncharacterized protein. (466 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (626 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (426 aa) |
| | C10orf90 | Chromosome 10 open reading frame 90. (758 aa) |
| | USP47 | Ubiquitin specific peptidase 47; Belongs to the peptidase C19 family. (1355 aa) |
| | CASP7 | Caspase 7; Belongs to the peptidase C14A family. (303 aa) |
| | TMEM161A | Transmembrane protein 161A. (462 aa) |
| | MMP2 | Matrix metallopeptidase 2. (661 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | N4BP1 | NEDD4 binding protein 1. (810 aa) |
| | DDB2 | Damage specific DNA binding protein 2. (427 aa) |
| | EP300 | E1A binding protein p300. (2416 aa) |
| | RBX1 | Ring-box 1. (108 aa) |
| | ATF4 | Activating transcription factor 4. (351 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1140 aa) |
