STRINGSTRING
HOXC9 HOXC9 FOXB1 FOXB1 NRARP NRARP TSHZ1 TSHZ1 FOXC1 FOXC1 BASP1 BASP1 FZD5 FZD5 NEUROD1 NEUROD1 ARC ARC FOXC2 FOXC2 MSGN1 MSGN1 TDRD15 TDRD15 NEUROG1 NEUROG1 NOG NOG HES4 HES4 SKI SKI HES5 HES5 HES3 HES3 HES2 HES2 CTNNBIP1 CTNNBIP1 FAM76A FAM76A HEYL HEYL ENSCSAP00000016711 ENSCSAP00000016711 WLS WLS CELSR2 CELSR2 HIPK1 HIPK1 TDRKH TDRKH TDRD10 TDRD10 TMED2 TMED2 KDM2B KDM2B CDON CDON TBX3 TBX3 HOXB9 HOXB9 HOXB8 HOXB8 HOXB7 HOXB7 HOXB6 HOXB6 HOXB5 HOXB5 HOXB4 HOXB4 HOXB3 HOXB3 HOXB2 HOXB2 HOXB1 HOXB1 PCGF2 PCGF2 TCAP TCAP ZBTB16 ZBTB16 ATM ATM HELT HELT KAT2A KAT2A MTHFSD MTHFSD FOXF1 FOXF1 SFRP2 SFRP2 FAM76B FAM76B MEOX1 MEOX1 SMAD4 SMAD4 SMAD2 SMAD2 CDX2 CDX2 CFC1 CFC1 MIB1 MIB1 PCDH8 PCDH8 LFNG LFNG RIPPLY2 RIPPLY2 TBX18 TBX18 MESP1 MESP1 MESP2 MESP2 NR2F2 NR2F2 GATA4 GATA4 CTNNB1 CTNNB1 PCSK6 PCSK6 EPB41L5 EPB41L5 EN1 EN1 WNT3A WNT3A HEY2 HEY2 MSX1 MSX1 NKX3-1 NKX3-1 TDGF1 TDGF1 ACVR2A ACVR2A COBL COBL NOTCH1 NOTCH1 AURKA AURKA GLI3 GLI3 PLXNA2 PLXNA2 SFRP1 SFRP1 PRKDC PRKDC BMP4 BMP4 OTX1 OTX1 SOX17 SOX17 OTX2 OTX2 ACVR2B ACVR2B HOXD13 HOXD13 HOXD11 HOXD11 HOXD10 HOXD10 HOXD9 HOXD9 HOXD8 HOXD8 HOXD4 HOXD4 HOXD3 HOXD3 BTG2 BTG2 HOXA11 HOXA11 HOXA10 HOXA10 HOXA7 HOXA7 HOXA6 HOXA6 HOXA5 HOXA5 HOXA4 HOXA4 HOXA3 HOXA3 HOXA2 HOXA2 ATP6AP2 ATP6AP2 KDM6A KDM6A PBX3 PBX3 BMP2 BMP2 CRB2 CRB2 HEY1 HEY1 MEOX2 MEOX2 TIFAB TIFAB SIX2 SIX2 ENSCSAP00000009499 ENSCSAP00000009499 SMAD3 SMAD3 WNT8A WNT8A CRKL CRKL WNT5A WNT5A RNF2 RNF2 TASOR TASOR PSEN1 PSEN1 POFUT1 POFUT1 TDRD6 TDRD6 TBXT TBXT TDRD5 TDRD5 FEZF2 FEZF2 ABI1 ABI1 ALDH1A2 ALDH1A2 SEMA3C SEMA3C DLL1 DLL1 TBX1 TBX1 CDX1 CDX1 SRF SRF C2orf66 C2orf66 PGAP1 PGAP1 MED12 MED12 TP53 TP53 TULP3 TULP3 TGFBR1 TGFBR1 PAX1 PAX1 FOXA2 FOXA2 CDX4 CDX4 HES7 HES7 PBX1 PBX1 FEZF1 FEZF1 BMPR2 BMPR2 TCF15 TCF15 SMO SMO GDF3 GDF3 BMPR1A BMPR1A MLLT3 MLLT3 RIPPLY1 RIPPLY1 CER1 CER1 LRP5 LRP5 HES1 HES1 LRP6 LRP6 PLD6 PLD6 ETS2 ETS2 HIPK2 HIPK2 FOXH1 FOXH1 NODAL NODAL OSR1 OSR1 PCSK5 PCSK5 BHLHE41 BHLHE41 ZIC3 ZIC3 DKK1 DKK1 BARX1 BARX1 POGLUT1 POGLUT1 PALB2 PALB2 XRCC2 XRCC2 HHEX HHEX CYP26C1 CYP26C1 SHH SHH NLE1 NLE1 GBX2 GBX2 WNT1 WNT1 TBX6 TBX6 HNF1B HNF1B HES6 HES6 EP300 EP300 ALX4 ALX4 RARG RARG FGF8 FGF8 LDB1 LDB1 HOXC13 HOXC13 HOXC8 HOXC8 HOXC11 HOXC11 HOXC10 HOXC10 HOXC6 HOXC6 HOXC5 HOXC5 HOXC4 HOXC4 GDF11 GDF11 WT1 WT1 PAX6 PAX6 TDRD1 TDRD1 GRSF1 GRSF1 DDIT3 DDIT3 EMX2 EMX2 TAF10 TAF10 FRS2 FRS2 BPTF BPTF AXIN2 AXIN2 LEF1 LEF1 MYF6 MYF6 MYF5 MYF5 DLL3 DLL3 WNT3 WNT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (260 aa)
FOXB1Forkhead box B1. (325 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
TSHZ1Teashirt zinc finger homeobox 1. (1064 aa)
FOXC1Forkhead box C1. (552 aa)
BASP1Brain abundant membrane attached signal protein 1. (227 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (585 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
ARCActivity regulated cytoskeleton associated protein. (396 aa)
FOXC2Forkhead box C2. (501 aa)
MSGN1Mesogenin 1. (193 aa)
TDRD15Tudor domain containing 15. (1935 aa)
NEUROG1Neurogenin 1. (237 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
HES4Hes family bHLH transcription factor 4. (221 aa)
SKISKI proto-oncogene. (728 aa)
HES5Hes family bHLH transcription factor 5. (166 aa)
HES3Hes family bHLH transcription factor 3. (197 aa)
HES2Hes family bHLH transcription factor 2. (173 aa)
CTNNBIP1Catenin beta interacting protein 1. (81 aa)
FAM76AFamily with sequence similarity 76 member A. (307 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (328 aa)
ENSCSAP00000016711Uncharacterized protein. (296 aa)
WLSWnt ligand secretion mediator. (564 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2757 aa)
HIPK1Homeodomain interacting protein kinase 1. (1210 aa)
TDRKHTudor and KH domain containing. (561 aa)
TDRD10Tudor domain containing 10. (366 aa)
TMED2Transmembrane p24 trafficking protein 2. (208 aa)
KDM2BLysine demethylase 2B. (1348 aa)
CDONCell adhesion associated, oncogene regulated. (1287 aa)
TBX3T-box transcription factor 3. (723 aa)
HOXB9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (250 aa)
HOXB8Homeobox B8. (243 aa)
HOXB7Homeobox B7. (217 aa)
HOXB6Homeobox B6. (224 aa)
HOXB5Homeobox B5. (269 aa)
HOXB4Homeobox B4. (251 aa)
HOXB3Homeobox B3. (431 aa)
HOXB2Homeobox B2. (356 aa)
HOXB1Homeobox B1. (304 aa)
PCGF2Polycomb group ring finger 2. (344 aa)
TCAPTitin-cap. (167 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
ATMSerine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa)
HELTHelt bHLH transcription factor. (327 aa)
KAT2AHistone acetyltransferase; Belongs to the acetyltransferase family. GCN5 subfamily. (837 aa)
MTHFSDMethenyltetrahydrofolate synthetase domain containing. (395 aa)
FOXF1Forkhead box F1. (354 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
FAM76BFamily with sequence similarity 76 member B. (323 aa)
MEOX1Mesenchyme homeobox 1. (254 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
CDX2Caudal type homeobox 2. (313 aa)
CFC1EGF-like domain-containing protein. (227 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
PCDH8Protocadherin 8. (1070 aa)
LFNGLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (236 aa)
RIPPLY2Ripply transcriptional repressor 2. (128 aa)
TBX18T-box transcription factor 18. (607 aa)
MESP1Mesoderm posterior bHLH transcription factor 1. (272 aa)
MESP2Uncharacterized protein. (205 aa)
NR2F2Nuclear receptor subfamily 2 group F member 2. (414 aa)
GATA4GATA binding protein 4. (442 aa)
CTNNB1Catenin beta 1. (781 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (839 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (699 aa)
EN1Homeobox protein engrailed-like. (395 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
MSX1Msh homeobox 1. (303 aa)
NKX3-1NK3 homeobox 1. (232 aa)
TDGF1Growth factor; Belongs to the EGF-CFC (Cripto-1/FRL1/Cryptic) family. (187 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
COBLCordon-bleu WH2 repeat protein. (1302 aa)
NOTCH1Notch receptor 1. (2555 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (403 aa)
GLI3GLI family zinc finger 3. (1459 aa)
PLXNA2Plexin A2. (1909 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4131 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
OTX1Orthodenticle homeobox 1. (354 aa)
SOX17SRY-box transcription factor 17. (412 aa)
OTX2Orthodenticle homeobox 2. (223 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)
HOXD13Homeobox D13. (343 aa)
HOXD11Homeobox D11. (338 aa)
HOXD10Homeobox D10. (340 aa)
HOXD9Homeobox D9. (343 aa)
HOXD8Homeobox D8. (290 aa)
HOXD4Homeobox D4. (255 aa)
HOXD3Homeobox D3. (432 aa)
BTG2BTG anti-proliferation factor 2. (158 aa)
HOXA11Homeobox A11. (310 aa)
HOXA10Homeobox domain-containing protein. (94 aa)
HOXA7Homeobox A7. (230 aa)
HOXA6Homeobox A6. (233 aa)
HOXA5Homeobox A5. (381 aa)
HOXA4Homeobox A4. (320 aa)
HOXA3Homeobox A3. (443 aa)
HOXA2Homeobox A2. (373 aa)
ATP6AP2ATPase H+ transporting accessory protein 2. (350 aa)
KDM6ALysine demethylase 6A. (1453 aa)
PBX3Homeobox domain-containing protein. (326 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
CRB2Crumbs cell polarity complex component 2. (1287 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
MEOX2Mesenchyme homeobox 2. (303 aa)
TIFABTIFA inhibitor. (161 aa)
SIX2SIX homeobox 2. (290 aa)
ENSCSAP00000009499Uncharacterized protein. (288 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
WNT8AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
RNF2Ring finger protein 2. (336 aa)
TASORTranscription activation suppressor. (1514 aa)
PSEN1Presenilin 1. (467 aa)
POFUT1Protein O-fucosyltransferase 1. (365 aa)
TDRD6Tudor domain containing 6. (2097 aa)
TBXTT-box transcription factor T. (436 aa)
TDRD5Tudor domain containing 5. (978 aa)
FEZF2FEZ family zinc finger 2. (458 aa)
ABI1Abl interactor 1. (508 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
TBX1T-box transcription factor 1. (490 aa)
CDX1Caudal type homeobox 1. (265 aa)
SRFSerum response factor. (508 aa)
C2orf66Chromosome 2 open reading frame 66. (113 aa)
PGAP1GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi. (922 aa)
MED12Mediator complex subunit 12. (2090 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (393 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (442 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
PAX1Paired box 1. (399 aa)
FOXA2Forkhead box A2. (463 aa)
CDX4Caudal type homeobox 4. (284 aa)
HES7Hes family bHLH transcription factor 7. (230 aa)
PBX1PBX homeobox 1. (301 aa)
FEZF1FEZ family zinc finger 1. (475 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
TCF15Transcription factor 15. (197 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
GDF3Growth differentiation factor 3. (364 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
MLLT3MLLT3 super elongation complex subunit. (543 aa)
RIPPLY1Uncharacterized protein. (80 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
LRP5LDL receptor related protein 5. (1451 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
LRP6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
PLD6Phospholipase D family member 6. (249 aa)
ETS2ETS proto-oncogene 2, transcription factor. (391 aa)
HIPK2Homeodomain interacting protein kinase 2. (1198 aa)
FOXH1Forkhead box H1. (365 aa)
NODALNodal growth differentiation factor. (347 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
PCSK5Proprotein convertase subtilisin/kexin type 5; Belongs to the peptidase S8 family. (1754 aa)
BHLHE41Basic helix-loop-helix family member e41. (482 aa)
ZIC3Zic family member 3. (466 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (266 aa)
BARX1BARX homeobox 1. (254 aa)
POGLUT1Protein O-glucosyltransferase 1. (392 aa)
PALB2Partner and localizer of BRCA2. (1183 aa)
XRCC2X-ray repair cross complementing 2. (280 aa)
HHEXHematopoietically expressed homeobox. (268 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
NLE1Notchless homolog 1. (487 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa)
TBX6T-box transcription factor 6. (436 aa)
HNF1BHNF1 homeobox B. (557 aa)
HES6Hes family bHLH transcription factor 6. (224 aa)
EP300E1A binding protein p300. (2416 aa)
ALX4ALX homeobox 4. (409 aa)
RARGRetinoic acid receptor gamma. (443 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
LDB1LIM domain binding 1. (411 aa)
HOXC13Homeobox C13. (329 aa)
HOXC8Homeobox C8. (242 aa)
HOXC11Homeobox C11. (304 aa)
HOXC10Homeobox C10. (342 aa)
HOXC6Homeobox C6. (235 aa)
HOXC5Homeobox C5. (202 aa)
HOXC4Homeobox C4. (264 aa)
GDF11Growth differentiation factor 11. (406 aa)
WT1WT1 transcription factor. (320 aa)
PAX6Paired box 6. (436 aa)
TDRD1Tudor domain containing 1. (1190 aa)
GRSF1G-rich RNA sequence binding factor 1. (479 aa)
DDIT3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (192 aa)
EMX2Empty spiracles homeobox 2. (252 aa)
TAF10Transcription initiation factor TFIID subunit 10; TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors; Belongs to the TAF10 family. (218 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
BPTFBromodomain PHD finger transcription factor. (2875 aa)
AXIN2Axin 2. (843 aa)
LEF1Lymphoid enhancer binding factor 1. (331 aa)
MYF6Myogenic factor 6. (241 aa)
MYF5Myogenic factor 5. (255 aa)
DLL3Delta like canonical Notch ligand 3. (614 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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