STRINGSTRING
ENSCSAP00000016815 ENSCSAP00000016815 NOG NOG ASCL1 ASCL1 GREM2 GREM2 FOXG1 FOXG1 GREM1 GREM1 INTU INTU SMAD2 SMAD2 ZFR ZFR WDR19 WDR19 CTNNB1 CTNNB1 GLI2 GLI2 EN1 EN1 BMP1 BMP1 WNT3A WNT3A TBC1D32 TBC1D32 DISP1 DISP1 ENSCSAP00000012074 ENSCSAP00000012074 AIDA AIDA ACVR1 ACVR1 LHX3 LHX3 NKX2-1 NKX2-1 TTC21B TTC21B FOXA1 FOXA1 NOTO NOTO GLI3 GLI3 VAX2 VAX2 SFRP1 SFRP1 TBX20 TBX20 BMP4 BMP4 HOXD11 HOXD11 HOXA11 HOXA11 HOXA2 HOXA2 IFT52 IFT52 CHRD CHRD LMX1B LMX1B SP8 SP8 LHX2 LHX2 SIX3 SIX3 SMAD6 SMAD6 AXIN1 AXIN1 PSEN1 PSEN1 OVOL2 OVOL2 MDFI MDFI TULP3 TULP3 NKX2-2 NKX2-2 ZFR2 ZFR2 GSC GSC SMO SMO BMPR1A BMPR1A WNT7A WNT7A CER1 CER1 DMRT3 DMRT3 DLL4 DLL4 EDN1 EDN1 SHH SHH PTCH1 PTCH1 ARL13B ARL13B LRP4 LRP4 WNT8B WNT8B FGF8 FGF8 FBXL15 FBXL15 SUFU SUFU FKBP8 FKBP8 PAX6 PAX6 DBX1 DBX1 GSX2 GSX2 GLI1 GLI1 BMPR1B BMPR1B CXXC4 CXXC4 WNT3 WNT3 HHIP HHIP TLL1 TLL1 DYNC2H1 DYNC2H1 RFX4 RFX4 FOXN4 FOXN4 DSCAML1 DSCAML1 TCTN1 TCTN1 HOXB2 HOXB2 NBL1 NBL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSCSAP00000016815RING-type domain-containing protein. (282 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (239 aa)
GREM2Gremlin. (168 aa)
FOXG1Forkhead box G1. (490 aa)
GREM1Gremlin. (184 aa)
INTUInturned planar cell polarity protein. (921 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ZFRZinc finger RNA binding protein. (1074 aa)
WDR19WD repeat domain 19. (1342 aa)
CTNNB1Catenin beta 1. (781 aa)
GLI2GLI family zinc finger 2. (1554 aa)
EN1Homeobox protein engrailed-like. (395 aa)
BMP1Metalloendopeptidase. (986 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
TBC1D32TBC1 domain family member 32. (968 aa)
DISP1SSD domain-containing protein. (1329 aa)
ENSCSAP00000012074Uncharacterized protein. (188 aa)
AIDAAxin interactor, dorsalization associated. (306 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
LHX3LIM homeobox 3. (402 aa)
NKX2-1NK2 homeobox 1. (371 aa)
TTC21BTetratricopeptide repeat domain 21B. (1316 aa)
FOXA1Forkhead box A1. (470 aa)
NOTONotochord homeobox. (251 aa)
GLI3GLI family zinc finger 3. (1459 aa)
VAX2Ventral anterior homeobox 2. (290 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
TBX20T-box transcription factor 20. (447 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
HOXD11Homeobox D11. (338 aa)
HOXA11Homeobox A11. (310 aa)
HOXA2Homeobox A2. (373 aa)
IFT52Intraflagellar transport 52. (442 aa)
CHRDChordin; Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. (956 aa)
LMX1BLIM homeobox transcription factor 1 beta. (402 aa)
SP8Sp8 transcription factor. (507 aa)
LHX2LIM homeobox 2. (406 aa)
SIX3SIX homeobox 3. (331 aa)
SMAD6Mothers against decapentaplegic homolog. (496 aa)
AXIN1Axin 1. (867 aa)
PSEN1Presenilin 1. (467 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
MDFIMyoD family inhibitor. (246 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (442 aa)
NKX2-2NK2 homeobox 2. (273 aa)
ZFR2Zinc finger RNA binding protein 2. (936 aa)
GSCGoosecoid homeobox. (259 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
CER1Cerberus 1, DAN family BMP antagonist. (267 aa)
DMRT3Doublesex and mab-3 related transcription factor 3. (472 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
EDN1Endothelin 1. (211 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
PTCH1Patched 1. (1452 aa)
ARL13BADP ribosylation factor like GTPase 13B. (428 aa)
LRP4LDL receptor related protein 4. (1669 aa)
WNT8BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
FBXL15F-box and leucine rich repeat protein 15. (300 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (484 aa)
FKBP8Peptidylprolyl isomerase. (413 aa)
PAX6Paired box 6. (436 aa)
DBX1Developing brain homeobox 1. (344 aa)
GSX2GS homeobox 2. (304 aa)
GLI1GLI family zinc finger 1. (1106 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
CXXC4CXXC finger protein 4. (198 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (353 aa)
HHIPHedgehog interacting protein. (682 aa)
TLL1Metalloendopeptidase. (1013 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4311 aa)
RFX4Regulatory factor X4. (738 aa)
FOXN4Forkhead box N4. (517 aa)
DSCAML1DS cell adhesion molecule like 1. (1886 aa)
TCTN1Tectonic family member 1. (587 aa)
HOXB2Homeobox B2. (356 aa)
NBL1Neuroblastoma suppressor of tumorigenicity 1. (181 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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