STRINGSTRING
MDK MDK NDNF NDNF ITGB3 ITGB3 DMP1 DMP1 HPSE HPSE DOCK1 DOCK1 UNC13D UNC13D CX3CL1 CX3CL1 KDR KDR ITGA3 ITGA3 FBLN1 FBLN1 ITGA5 ITGA5 HSD17B12 HSD17B12 PTPRJ PTPRJ COL8A1 COL8A1 ABI3BP ABI3BP PDGFB PDGFB CALR CALR FLNA FLNA FMN1 FMN1 DNM2 DNM2 ENSCSAP00000003244 ENSCSAP00000003244 TRIOBP TRIOBP GSK3B GSK3B ITGB1BP1 ITGB1BP1 NINJ1 NINJ1 EPHA1 EPHA1 ECM2 ECM2 POLDIP2 POLDIP2 RREB1 RREB1 NEDD9 NEDD9 ARL2 ARL2 CARMIL1 CARMIL1 EFEMP2 EFEMP2 ENSCSAP00000004411 ENSCSAP00000004411 BRAF BRAF SPOCK2 SPOCK2 EMP2 EMP2 JAK2 JAK2 ARPC2 ARPC2 TSTA3 TSTA3 FN1 FN1 ENSCSAP00000005586 ENSCSAP00000005586 FBLN2 FBLN2 EMILIN1 EMILIN1 NID1 NID1 TEK TEK EMID1 EMID1 CCL21 CCL21 DISC1 DISC1 TESK1 TESK1 HAS2 HAS2 NRP1 NRP1 RIN2 RIN2 MYOC MYOC VIT VIT CD36 CD36 VEGFA VEGFA RELL2 RELL2 CDK6 CDK6 HACD1 HACD1 RSU1 RSU1 C1QBP C1QBP ALOX15 ALOX15 CRKL CRKL SMAD3 SMAD3 PRKCE PRKCE AGR2 AGR2 FERMT1 FERMT1 PPM1F PPM1F CRK CRK DMD DMD HRG HRG ENSCSAP00000010271 ENSCSAP00000010271 SDC4 SDC4 ABL1 ABL1 EDIL3 EDIL3 PREX1 PREX1 FERMT2 FERMT2 DAG1 DAG1 TSC1 TSC1 SFRP1 SFRP1 EGFL6 EGFL6 PLEKHA2 PLEKHA2 CASS4 CASS4 VWC2 VWC2 CSPG5 CSPG5 PTK2B PTK2B DOCK5 DOCK5 DMTN DMTN EPB41L5 EPB41L5 CCL28 CCL28 LIMS2 LIMS2 DAB2 DAB2 EGFLAM EGFLAM LIMS1 LIMS1 CIB1 CIB1 UTRN UTRN MAP4K4 MAP4K4 ARHGEF7 ARHGEF7 ROCK1 ROCK1 OLFM4 OLFM4 ENSCSAP00000014056 ENSCSAP00000014056 CCDC80 CCDC80 ENSCSAP00000014535 ENSCSAP00000014535 FGB FGB FGA FGA FGG FGG FOXF1 FOXF1 JUP JUP CCR7 CCR7 CD3E CD3E SKAP1 SKAP1 THY1 THY1 RRAS RRAS P4HB P4HB LRRC45 LRRC45 RAC3 RAC3 S100A10 S100A10 CSF1 CSF1 CCN1 CCN1 COL16A1 COL16A1 WNT4 WNT4 CDC42 CDC42 PRKCZ PRKCZ ENSCSAP00000019137 ENSCSAP00000019137 FUT1 FUT1 MYADM MYADM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MDKUncharacterized protein. (159 aa)
NDNFNeuron derived neurotrophic factor. (577 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (741 aa)
DMP1Dentin matrix acidic phosphoprotein 1. (506 aa)
HPSEHeparanase. (546 aa)
DOCK1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1330 aa)
UNC13DUnc-13 homolog D. (1071 aa)
CX3CL1C-X3-C motif chemokine ligand 1. (402 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
ITGA3Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1049 aa)
FBLN1Fibulin-1; Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. (703 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1098 aa)
HSD17B12Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa)
PTPRJProtein tyrosine phosphatase receptor type J. (1333 aa)
COL8A1Collagen type VIII alpha 1 chain. (746 aa)
ABI3BPABI family member 3 binding protein. (1753 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
CALRCalreticulin. (417 aa)
FLNAFilamin A. (2639 aa)
FMN1Formin 1. (1291 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (880 aa)
ENSCSAP00000003244Uncharacterized protein. (124 aa)
TRIOBPTRIO and F-actin binding protein. (2192 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
NINJ1Ninjurin 1. (152 aa)
EPHA1EPH receptor A1. (979 aa)
ECM2Extracellular matrix protein 2. (677 aa)
POLDIP2DNA polymerase delta interacting protein 2. (408 aa)
RREB1Ras responsive element binding protein 1. (1742 aa)
NEDD9Neural precursor cell expressed, developmentally down-regulated 9. (834 aa)
ARL2ADP ribosylation factor like GTPase 2; Belongs to the small GTPase superfamily. Arf family. (184 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1424 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
ENSCSAP00000004411SCY domain-containing protein. (142 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (482 aa)
SPOCK2SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (421 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (300 aa)
TSTA3Tissue specific transplantation antigen P35B. (321 aa)
FN1Fibronectin 1. (2265 aa)
ENSCSAP00000005586Uncharacterized protein. (163 aa)
FBLN2Fibulin 2. (1225 aa)
EMILIN1Elastin microfibril interfacer 1. (860 aa)
NID1Nidogen 1. (1249 aa)
TEKTEK receptor tyrosine kinase. (1123 aa)
EMID1EMI domain containing 1. (443 aa)
CCL21C-C motif chemokine ligand 21. (131 aa)
DISC1DISC1 scaffold protein. (639 aa)
TESK1Testis associated actin remodelling kinase 1. (626 aa)
HAS2Hyaluronan synthase 2. (552 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
RIN2Ras and Rab interactor 2. (895 aa)
MYOCMyocilin. (491 aa)
VITVitrin. (696 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (395 aa)
RELL2RELT like 2. (276 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (326 aa)
HACD1Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (288 aa)
RSU1Ras suppressor protein 1. (277 aa)
C1QBPComplement C1q binding protein. (281 aa)
ALOX15Arachidonate 15-lipoxygenase. (610 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
PRKCEProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (599 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (175 aa)
FERMT1Fermitin family member 1. (677 aa)
PPM1FProtein phosphatase, Mg2+/Mn2+ dependent 1F. (455 aa)
CRKCRK proto-oncogene, adaptor protein. (204 aa)
DMDUncharacterized protein. (774 aa)
HRGHistidine rich glycoprotein. (521 aa)
ENSCSAP00000010271ZZ-type domain-containing protein. (595 aa)
SDC4Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (198 aa)
ABL1Tyrosine-protein kinase. (1130 aa)
EDIL3EGF like repeats and discoidin domains 3. (480 aa)
PREX1Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1. (1661 aa)
FERMT2Fermitin family member 2. (507 aa)
DAG1Dystroglycan 1. (894 aa)
TSC1TSC complex subunit 1. (1164 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
EGFL6EGF like domain multiple 6. (553 aa)
PLEKHA2Pleckstrin homology domain containing A2. (425 aa)
CASS4Cas scaffold protein family member 4. (786 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
CSPG5Chondroitin sulfate proteoglycan 5. (562 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1018 aa)
DOCK5Dedicator of cytokinesis 5; Belongs to the DOCK family. (1870 aa)
DMTNDematin actin binding protein. (323 aa)
EPB41L5Erythrocyte membrane protein band 4.1 like 5. (699 aa)
CCL28C-C motif chemokine. (129 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (341 aa)
DAB2DAB adaptor protein 2. (770 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (1009 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (337 aa)
CIB1Calcium and integrin binding 1. (191 aa)
UTRNUtrophin. (3434 aa)
MAP4K4Mitogen-activated protein kinase kinase kinase kinase 4. (1382 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (862 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1354 aa)
OLFM4Olfactomedin 4. (508 aa)
ENSCSAP00000014056Uncharacterized protein. (313 aa)
CCDC80Coiled-coil domain containing 80. (660 aa)
ENSCSAP00000014535Uncharacterized protein. (344 aa)
FGBFibrinogen beta chain. (491 aa)
FGAFibrinogen alpha chain. (875 aa)
FGGFibrinogen gamma chain. (437 aa)
FOXF1Forkhead box F1. (354 aa)
JUPJunction plakoglobin. (745 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
CD3ECD3e molecule. (197 aa)
SKAP1Src kinase associated phosphoprotein 1. (266 aa)
THY1Thy-1 cell surface antigen. (161 aa)
RRASRAS related. (218 aa)
P4HBProtein disulfide-isomerase. (510 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
RAC3Rac family small GTPase 3. (192 aa)
S100A10S_100 domain-containing protein; Belongs to the S-100 family. (199 aa)
CSF1Macrophage colony-stimulating factor 1; Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female [...] (560 aa)
CCN1Cellular communication network factor 1. (381 aa)
COL16A1LAM_G_DOMAIN domain-containing protein. (868 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa)
CDC42Cell division cycle 42. (191 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. (488 aa)
ENSCSAP00000019137L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (357 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (366 aa)
MYADMMyeloid associated differentiation marker. (322 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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