STRINGSTRING
INHBA INHBA BMP7 BMP7 TGFB2 TGFB2 RBPMS RBPMS ACVR1 ACVR1 ACVR2A ACVR2A LEFTY1 LEFTY1 LEFTY2 LEFTY2 INHBB INHBB DAB2 DAB2 TWSG1 TWSG1 SMAD4 SMAD4 TGFB1 TGFB1 ENSCSAP00000016878 ENSCSAP00000016878 ENSCSAP00000016884 ENSCSAP00000016884 ENSCSAP00000016885 ENSCSAP00000016885 SDCBP SDCBP BMPR1A BMPR1A TGFBR2 TGFBR2 NODAL NODAL GDF7 GDF7 INHA INHA HFE HFE BMP6 BMP6 ACVRL1 ACVRL1 GDF11 GDF11 INHBC INHBC GDF2 GDF2 INHBE INHBE BMP3 BMP3 GDF10 GDF10 GDF3 GDF3 GDF5 GDF5 BMPR2 BMPR2 TGFBR1 TGFBR1 TGFB3 TGFB3 GDF6 GDF6 BMP15 BMP15 BMP5 BMP5 BMP2 BMP2 ENG ENG ENSCSAP00000010642 ENSCSAP00000010642 BMP4 BMP4 BMP10 BMP10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
INHBAInhibin subunit beta A. (426 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
RBPMSRNA binding protein, mRNA processing factor. (219 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
LEFTY1Left-right determination factor. (366 aa)
LEFTY2Left-right determination factor. (366 aa)
INHBBInhibin subunit beta B. (320 aa)
DAB2DAB adaptor protein 2. (770 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
ENSCSAP00000016878TGF_BETA_2 domain-containing protein. (354 aa)
ENSCSAP00000016884TGF_BETA_2 domain-containing protein. (292 aa)
ENSCSAP00000016885TGFb_propeptide domain-containing protein. (144 aa)
SDCBPUncharacterized protein. (293 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
NODALNodal growth differentiation factor. (347 aa)
GDF7Growth differentiation factor 7. (447 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (366 aa)
HFEHomeostatic iron regulator; Belongs to the MHC class I family. (300 aa)
BMP6Bone morphogenetic protein 6. (433 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
GDF11Growth differentiation factor 11. (406 aa)
INHBCInhibin subunit beta C. (352 aa)
GDF2Growth differentiation factor 2. (429 aa)
INHBEInhibin subunit beta E. (351 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (474 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (477 aa)
GDF3Growth differentiation factor 3. (364 aa)
GDF5Growth differentiation factor 5. (499 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
GDF6Growth differentiation factor 6. (455 aa)
BMP15Bone morphogenetic protein 15. (393 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
BMP2Bone morphogenetic protein 2. (396 aa)
ENGEndoglin. (658 aa)
ENSCSAP00000010642Uncharacterized protein. (241 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
BMP10Bone morphogenetic protein 10. (424 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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