STRINGSTRING
PHACTR4 PHACTR4 FOXC1 FOXC1 FOXC2 FOXC2 CITED2 CITED2 SOX11 SOX11 PEF1 PEF1 SEMA6C SEMA6C SEMA4A SEMA4A CORO1C CORO1C HAND2 HAND2 EDNRA EDNRA CDH2 CDH2 RADIL RADIL EDNRB EDNRB PDCD6 PDCD6 SEMA5A SEMA5A SEMA4C SEMA4C SEMA4B SEMA4B PHOX2B PHOX2B GDNF GDNF ISL1 ISL1 TAPT1 TAPT1 ACVR1 ACVR1 KITLG KITLG PITX2 PITX2 ALX1 ALX1 NOLC1 NOLC1 SEMA4G SEMA4G MAPK3 MAPK3 GBX2 GBX2 SHH SHH CYP26C1 CYP26C1 HTR2B HTR2B SOX10 SOX10 SEMA4D SEMA4D SEMA5B SEMA5B EDN1 EDN1 FN1 FN1 FGF19 FGF19 ERBB4 ERBB4 ENSCSAP00000005731 ENSCSAP00000005731 BMPR1A BMPR1A NRTN NRTN SMO SMO NRP2 NRP2 SEMA6B SEMA6B RET RET ANXA6 ANXA6 NRP1 NRP1 OVOL2 OVOL2 TCOF1 TCOF1 KBTBD8 KBTBD8 TBX1 TBX1 EFNB1 EFNB1 SOX8 SOX8 SEMA3C SEMA3C ALDH1A2 ALDH1A2 SEMA3E SEMA3E SEMA3A SEMA3A SEMA3D SEMA3D SEMA3G SEMA3G RDH10 RDH10 MAPK1 MAPK1 JAG1 JAG1 HIF1A HIF1A SEMA7A SEMA7A KLHL12 KLHL12 SEMA3B SEMA3B SEMA3F SEMA3F FAM172A FAM172A SEMA6A SEMA6A SNAI2 SNAI2 ENSCSAP00000011447 ENSCSAP00000011447 EDN3 EDN3 SEMA4F SEMA4F NRG1 NRG1 LAMA5 LAMA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PHACTR4Phosphatase and actin regulator. (685 aa)
FOXC1Forkhead box C1. (552 aa)
FOXC2Forkhead box C2. (501 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (273 aa)
SOX11Transcription factor SOX. (441 aa)
PEF1Penta-EF-hand domain containing 1. (283 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (931 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (810 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (483 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (906 aa)
RADILRap associating with DIL domain. (1100 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (442 aa)
PDCD6Programmed cell death 6. (136 aa)
SEMA5ASemaphorin 5A. (1074 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (833 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (836 aa)
PHOX2BPaired like homeobox 2B. (314 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
ISL1ISL LIM homeobox 1. (349 aa)
TAPT1Transmembrane anterior posterior transformation 1. (674 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
PITX2Homeobox protein. (325 aa)
ALX1ALX homeobox 1. (327 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (714 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (810 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (379 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (522 aa)
HTR2B5-hydroxytryptamine receptor 2B. (481 aa)
SOX10SRY-box transcription factor 10. (236 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (862 aa)
SEMA5BSemaphorin 5B. (1152 aa)
EDN1Endothelin 1. (211 aa)
FN1Fibronectin 1. (2265 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
ERBB4Protein kinase domain-containing protein. (622 aa)
ENSCSAP00000005731Protein kinase domain-containing protein. (479 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
NRTNNeurturin. (197 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (901 aa)
SEMA6BSema domain-containing protein; Belongs to the semaphorin family. (374 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1099 aa)
ANXA6Annexin. (676 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
OVOL2Ovo like zinc finger 2. (275 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1524 aa)
KBTBD8Kelch repeat and BTB domain containing 8. (575 aa)
TBX1T-box transcription factor 1. (490 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (346 aa)
SOX8SRY-box transcription factor 8. (446 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (715 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (746 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (777 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (782 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (360 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (826 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (501 aa)
KLHL12BTB domain-containing protein. (527 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (748 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (754 aa)
FAM172AFamily with sequence similarity 172 member A. (450 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1043 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
ENSCSAP00000011447Uncharacterized protein. (637 aa)
EDN3Endothelin 3. (230 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
NRG1Neuregulin 1. (467 aa)
LAMA5Laminin subunit alpha 5. (3694 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.