STRINGSTRING
LEPROT LEPROT ZFYVE9 ZFYVE9 EPS15 EPS15 TINAGL1 TINAGL1 TMEM50A TMEM50A VAMP3 VAMP3 ENSCSAP00000017966 ENSCSAP00000017966 LOC103214510 LOC103214510 ARL4C ARL4C MAGEL2 MAGEL2 PHETA1 PHETA1 PHETA2 PHETA2 ARF6 ARF6 ENSCSAP00000018972 ENSCSAP00000018972 ANKRD63 ANKRD63 RAB9A RAB9A PICALM PICALM KIAA1109 KIAA1109 RASSF9 RASSF9 VPS4A VPS4A LAMTOR1 LAMTOR1 GRIP1 GRIP1 DENND5A DENND5A ENSCSAP00000000931 ENSCSAP00000000931 AGAP2 AGAP2 GGA3 GGA3 ENSCSAP00000001087 ENSCSAP00000001087 ANKRD27 ANKRD27 UBE2O UBE2O TSG101 TSG101 VTI1A VTI1A GBF1 GBF1 SPAG9 SPAG9 VPS35 VPS35 MVB12A MVB12A ARHGAP1 ARHGAP1 EPS15L1 EPS15L1 CLTC CLTC TBC1D23 TBC1D23 TBC1D10B TBC1D10B RAB17 RAB17 STX10 STX10 RAB11FIP4 RAB11FIP4 CALY CALY STX5 STX5 MICALL1 MICALL1 EIPR1 EIPR1 GGA1 GGA1 EHD1 EHD1 VPS51 VPS51 VPS35L VPS35L VPS26A VPS26A TRAPPC10 TRAPPC10 GOLT1B GOLT1B SNX4 SNX4 AP5B1 AP5B1 SNX32 SNX32 TRIM27 TRIM27 LAPTM4A LAPTM4A EHD4 EHD4 TOM1 TOM1 DENND2A DENND2A CLEC16A CLEC16A VPS28 VPS28 ITSN2 ITSN2 VPS39 VPS39 VPS26C VPS26C TMEM87A TMEM87A TBC1D10C TBC1D10C RAB7A RAB7A RAB10 RAB10 ACAP2 ACAP2 SCRIB SCRIB RIC1 RIC1 ARHGAP44 ARHGAP44 TMCC1 TMCC1 RBSN RBSN GRIP2 GRIP2 ENSCSAP00000005665 ENSCSAP00000005665 TBC1D10A TBC1D10A NSG2 NSG2 VPS52 VPS52 DENND1C DENND1C CMTM6 CMTM6 SRL SRL LYST LYST TMEM50B TMEM50B SNX17 SNX17 ITSN1 ITSN1 ANXA8L1 ANXA8L1 TBC1D5 TBC1D5 UBAP1 UBAP1 PIKFYVE PIKFYVE VCP VCP UBXN6 UBXN6 ENSCSAP00000006780 ENSCSAP00000006780 ALS2 ALS2 RGP1 RGP1 ENSCSAP00000006899 ENSCSAP00000006899 RAB6B RAB6B CRACR2A CRACR2A EHD3 EHD3 ABCA1 ABCA1 ENSCSAP00000007692 ENSCSAP00000007692 CLTCL1 CLTCL1 SNX12 SNX12 SNX5 SNX5 RAB41 RAB41 VAMP4 VAMP4 ERC1 ERC1 PLEKHJ1 PLEKHJ1 BAIAP3 BAIAP3 AP3D1 AP3D1 HEATR5B HEATR5B WASHC1 WASHC1 CHMP4B CHMP4B RAB8B RAB8B SNX30 SNX30 LAPTM4B LAPTM4B STX6 STX6 SNX1 SNX1 STAM STAM VPS50 VPS50 RAB11FIP3 RAB11FIP3 ENSCSAP00000008966 ENSCSAP00000008966 CCDC22 CCDC22 AP5S1 AP5S1 GRIPAP1 GRIPAP1 SNX9 SNX9 LRRC1 LRRC1 ANKFY1 ANKFY1 WAS WAS CHMP4C CHMP4C VTI1B VTI1B RAB14 RAB14 PREPL PREPL VPS16 VPS16 DENND1A DENND1A DENND1B DENND1B MVB12B MVB12B SGSM2 SGSM2 RILP RILP TRARG1 TRARG1 VPS53 VPS53 RHOBTB3 RHOBTB3 GOLT1A GOLT1A AP5M1 AP5M1 SNX33 SNX33 SNX2 SNX2 RAB29 RAB29 VPS54 VPS54 REPS2 REPS2 RAB7B RAB7B ZFYVE16 ZFYVE16 AP3B1 AP3B1 ALMS1 ALMS1 DCTN1 DCTN1 STX16 STX16 YKT6 YKT6 SNX6 SNX6 HEATR5A HEATR5A ENTR1 ENTR1 LEPROTL1 LEPROTL1 CHMP4A CHMP4A STAM2 STAM2 PTPN23 PTPN23 TBC1D14 TBC1D14 ALS2CL ALS2CL NSG1 NSG1 CCDC93 CCDC93 SNX18 SNX18 ARFRP1 ARFRP1 VPS37A VPS37A TMEM87B TMEM87B GCC2 GCC2 REPS1 REPS1 VTA1 VTA1 MICALL2 MICALL2 SNX8 SNX8 AP5Z1 AP5Z1 VPS36 VPS36 ATP6AP1 ATP6AP1 LMTK2 LMTK2 DCLK1 DCLK1 EPG5 EPG5 MYO5B MYO5B SLC66A2 SLC66A2 ANKRD50 ANKRD50 ARL1 ARL1 VPS25 VPS25 WASHC3 WASHC3 WASHC4 WASHC4 EHD2 EHD2 CORO1C CORO1C VPS29 VPS29 SNF8 SNF8 TBC1D17 TBC1D17 RAB35 RAB35 HGS HGS VPS26B VPS26B VPS37B VPS37B RILPL1 RILPL1 RAB13 RAB13 SNX27 SNX27 CHMP2A CHMP2A SORT1 SORT1 EVI5 EVI5 BTBD8 BTBD8
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LEPROTLeptin receptor overlapping transcript. (131 aa)
ZFYVE9Zinc finger FYVE domain-containing protein. (1380 aa)
EPS15Epidermal growth factor receptor pathway substrate 15. (897 aa)
TINAGL1Tubulointerstitial nephritis antigen like 1; Belongs to the peptidase C1 family. (467 aa)
TMEM50ATransmembrane protein 50A. (157 aa)
VAMP3Vesicle associated membrane protein 3. (100 aa)
ENSCSAP00000017966PX domain-containing protein. (162 aa)
LOC103214510RING-type domain-containing protein. (311 aa)
ARL4CADP ribosylation factor like GTPase 4C; Belongs to the small GTPase superfamily. Arf family. (192 aa)
MAGEL2MAGE domain-containing protein. (645 aa)
PHETA1PH domain containing endocytic trafficking adaptor 1. (247 aa)
PHETA2PH domain containing endocytic trafficking adaptor 2. (259 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
ENSCSAP00000018972UDENN domain-containing protein. (357 aa)
ANKRD63Ankyrin repeat domain 63. (382 aa)
RAB9ARAB9A, member RAS oncogene family. (201 aa)
PICALMPhosphatidylinositol binding clathrin assembly protein. (660 aa)
KIAA1109KIAA1109. (4812 aa)
RASSF9Ras association domain family member 9. (435 aa)
VPS4AUncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
LAMTOR1Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1. (161 aa)
GRIP1Glutamate receptor interacting protein 1. (1113 aa)
DENND5ADENN domain containing 5A. (761 aa)
ENSCSAP00000000931PX domain-containing protein. (343 aa)
AGAP2ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1195 aa)
GGA3Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (723 aa)
ENSCSAP00000001087UDENN domain-containing protein. (357 aa)
ANKRD27Ankyrin repeat domain 27. (1046 aa)
UBE2OUbiquitin conjugating enzyme E2 O. (1293 aa)
TSG101Tumor susceptibility 101. (390 aa)
VTI1AVesicle transport through interaction with t-SNAREs 1A. (224 aa)
GBF1Golgi brefeldin A resistant guanine nucleotide exchange factor 1. (1856 aa)
SPAG9Sperm associated antigen 9. (1334 aa)
VPS35Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
MVB12AMultivesicular body subunit 12A. (273 aa)
ARHGAP1Rho GTPase activating protein 1. (439 aa)
EPS15L1Epidermal growth factor receptor pathway substrate 15 like 1. (926 aa)
CLTCClathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1495 aa)
TBC1D23TBC1 domain family member 23. (699 aa)
TBC1D10BTBC1 domain family member 10B. (815 aa)
RAB17RAB17, member RAS oncogene family. (212 aa)
STX10Syntaxin 10; Belongs to the syntaxin family. (249 aa)
RAB11FIP4RAB11 family interacting protein 4. (557 aa)
CALYCalcyon neuron specific vesicular protein. (217 aa)
STX5Syntaxin 5; Belongs to the syntaxin family. (355 aa)
MICALL1MICAL like 1. (863 aa)
EIPR1EARP complex and GARP complex interacting protein 1. (387 aa)
GGA1Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (639 aa)
EHD1EH domain containing 1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (534 aa)
VPS51VPS51 subunit of GARP complex. (806 aa)
VPS35LVPS35 endosomal protein sorting factor like. (980 aa)
VPS26AVPS26, retromer complex component A. (327 aa)
TRAPPC10Uncharacterized protein. (1259 aa)
GOLT1BGolgi transport 1B. (138 aa)
SNX4Sorting nexin 4. (450 aa)
AP5B1Adaptor related protein complex 5 subunit beta 1. (878 aa)
SNX32Sorting nexin; Involved in several stages of intracellular trafficking. (403 aa)
TRIM27Tripartite motif containing 27. (513 aa)
LAPTM4ALysosomal protein transmembrane 4 alpha. (233 aa)
EHD4EH domain containing 4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (541 aa)
TOM1Target of myb1 membrane trafficking protein; Belongs to the TOM1 family. (510 aa)
DENND2ADENN domain containing 2A. (675 aa)
CLEC16AC-type lectin domain containing 16A. (1035 aa)
VPS28Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (231 aa)
ITSN2Intersectin 2. (1684 aa)
VPS39VPS39 subunit of HOPS complex. (751 aa)
VPS26CVPS26 endosomal protein sorting factor C. (297 aa)
TMEM87ATransmembrane protein 87A. (555 aa)
TBC1D10CTBC1 domain family member 10C. (446 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
RAB10RAB10, member RAS oncogene family. (200 aa)
ACAP2ArfGAP with coiled-coil, ankyrin repeat and PH domains 2. (813 aa)
SCRIBScribble planar cell polarity protein. (1678 aa)
RIC1RIC1 homolog, RAB6A GEF complex partner 1. (1422 aa)
ARHGAP44Rho GTPase activating protein 44. (774 aa)
TMCC1Transmembrane and coiled-coil domain family 1. (329 aa)
RBSNRabenosyn, RAB effector. (785 aa)
GRIP2Glutamate receptor interacting protein 2. (1048 aa)
ENSCSAP00000005665WASH_WAHD domain-containing protein. (317 aa)
TBC1D10ATBC1 domain family member 10A. (508 aa)
NSG2Neuronal vesicle trafficking associated 2. (171 aa)
VPS52VPS52 subunit of GARP complex. (723 aa)
DENND1CDENN domain containing 1C. (757 aa)
CMTM6CKLF like MARVEL transmembrane domain containing 6. (183 aa)
SRLDynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (980 aa)
LYSTLysosomal trafficking regulator. (3804 aa)
TMEM50BTransmembrane protein 50B. (158 aa)
SNX17Sorting nexin 17. (470 aa)
ITSN1Intersectin 1. (1649 aa)
ANXA8L1Annexin. (327 aa)
TBC1D5TBC1 domain family member 5. (797 aa)
UBAP1Ubiquitin associated protein 1. (502 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2098 aa)
VCPValosin containing protein; Belongs to the AAA ATPase family. (806 aa)
UBXN6UBX domain protein 6. (441 aa)
ENSCSAP00000006780Uncharacterized protein. (812 aa)
ALS2VPS9 domain-containing protein. (881 aa)
RGP1RGP1 homolog, RAB6A GEF complex partner 1. (391 aa)
ENSCSAP00000006899CAP-ZIP_m domain-containing protein. (1334 aa)
RAB6BRAB6B, member RAS oncogene family. (208 aa)
CRACR2ACalcium release activated channel regulator 2A. (734 aa)
EHD3EH domain containing 3; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (535 aa)
ABCA1ATP binding cassette subfamily A member 1. (2261 aa)
ENSCSAP00000007692Uncharacterized protein. (192 aa)
CLTCL1Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1914 aa)
SNX12PX domain-containing protein. (85 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (404 aa)
RAB41RAB41, member RAS oncogene family. (221 aa)
VAMP4Vesicle associated membrane protein 4. (141 aa)
ERC1ELKS/RAB6-interacting/CAST family member 1. (1120 aa)
PLEKHJ1PH domain-containing protein. (149 aa)
BAIAP3BAI1 associated protein 3. (1152 aa)
AP3D1AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane. (1219 aa)
HEATR5BHEAT repeat containing 5B. (2161 aa)
WASHC1WASH complex subunit 1. (478 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
RAB8BRAB8B, member RAS oncogene family. (207 aa)
SNX30Sorting nexin family member 30. (393 aa)
LAPTM4BLysosomal protein transmembrane 4 beta. (226 aa)
STX6Syntaxin 6; Belongs to the syntaxin family. (244 aa)
SNX1Sorting nexin 1. (522 aa)
STAMSignal transducing adaptor molecule. (540 aa)
VPS50VPS50 subunit of EARP/GARPII complex. (964 aa)
RAB11FIP3RAB11 family interacting protein 3. (491 aa)
ENSCSAP00000008966RING-type domain-containing protein. (323 aa)
CCDC22Coiled-coil domain containing 22. (627 aa)
AP5S1Adaptor related protein complex 5 subunit sigma 1. (200 aa)
GRIPAP1GRIP1 associated protein 1. (840 aa)
SNX9Sorting nexin. (618 aa)
LRRC1Leucine rich repeat containing 1. (524 aa)
ANKFY1Ankyrin repeat and FYVE domain containing 1. (1169 aa)
WASWASP actin nucleation promoting factor. (502 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
VTI1BVesicle transport through interaction with t-SNAREs 1B. (232 aa)
RAB14RAB14, member RAS oncogene family. (215 aa)
PREPLProlyl endopeptidase like. (727 aa)
VPS16Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa)
DENND1ADENN domain containing 1A. (1058 aa)
DENND1BDENN domain containing 1B. (759 aa)
MVB12BMultivesicular body subunit 12B. (321 aa)
SGSM2Small G protein signaling modulator 2. (1052 aa)
RILPRab interacting lysosomal protein. (395 aa)
TRARG1Trafficking regulator of GLUT4 (SLC2A4) 1. (235 aa)
VPS53VPS53 subunit of GARP complex. (832 aa)
RHOBTB3Rho related BTB domain containing 3. (611 aa)
GOLT1AGolgi transport 1A. (132 aa)
AP5M1Adaptor related protein complex 5 subunit mu 1; Belongs to the adaptor complexes medium subunit family. (490 aa)
SNX33Sorting nexin. (574 aa)
SNX2Sorting nexin 2. (519 aa)
RAB29RAB29, member RAS oncogene family. (203 aa)
VPS54VPS54 subunit of GARP complex. (965 aa)
REPS2RALBP1 associated Eps domain containing 2. (521 aa)
RAB7BRAB7B, member RAS oncogene family. (199 aa)
ZFYVE16Zinc finger FYVE-type containing 16. (1540 aa)
AP3B1AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1094 aa)
ALMS1ALMS1 centrosome and basal body associated protein. (4031 aa)
DCTN1CAP-Gly domain-containing protein. (1433 aa)
STX16Syntaxin 16; Belongs to the syntaxin family. (304 aa)
YKT6YKT6 v-SNARE homolog; Belongs to the synaptobrevin family. (198 aa)
SNX6Sorting nexin 6. (298 aa)
HEATR5AHEAT repeat containing 5A. (2046 aa)
ENTR1Endosome associated trafficking regulator 1. (354 aa)
LEPROTL1Leptin receptor overlapping transcript like 1. (131 aa)
CHMP4ACharged multivesicular body protein 4A. (222 aa)
STAM2Signal transducing adaptor molecule 2. (525 aa)
PTPN23Protein tyrosine phosphatase non-receptor type 23. (1632 aa)
TBC1D14TBC1 domain family member 14. (693 aa)
ALS2CLALS2 C-terminal like. (844 aa)
NSG1Neuronal vesicle trafficking associated 1. (185 aa)
CCDC93Coiled-coil domain containing 93. (631 aa)
SNX18Sorting nexin. (624 aa)
ARFRP1ADP ribosylation factor related protein 1. (201 aa)
VPS37AVPS37A subunit of ESCRT-I. (396 aa)
TMEM87BTransmembrane protein 87B. (556 aa)
GCC2GRIP and coiled-coil domain containing 2. (1685 aa)
REPS1RALBP1 associated Eps domain containing 1. (796 aa)
VTA1Vesicle trafficking 1. (307 aa)
MICALL2MICAL like 2. (908 aa)
SNX8Sorting nexin 8. (412 aa)
AP5Z1Adaptor related protein complex 5 subunit zeta 1. (808 aa)
VPS36Vacuolar protein sorting 36 homolog. (386 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (475 aa)
LMTK2Lemur tyrosine kinase 2. (1502 aa)
DCLK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (487 aa)
EPG5Ectopic P-granules autophagy protein 5 homolog. (2579 aa)
MYO5BUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1823 aa)
SLC66A2Solute carrier family 66 member 2. (271 aa)
ANKRD50Ankyrin repeat domain 50. (1429 aa)
ARL1ADP ribosylation factor like GTPase 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
WASHC3WASH complex subunit 3. (194 aa)
WASHC4WASH complex subunit 4. (1173 aa)
EHD2EH domain containing 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (543 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (483 aa)
VPS29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (117 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
TBC1D17TBC1 domain family member 17. (648 aa)
RAB35RAB35, member RAS oncogene family. (201 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (777 aa)
VPS26BVPS26, retromer complex component B. (336 aa)
VPS37BVPS37B subunit of ESCRT-I. (285 aa)
RILPL1Rab interacting lysosomal protein like 1. (385 aa)
RAB13Uncharacterized protein. (245 aa)
SNX27Sorting nexin 27. (528 aa)
CHMP2ACharged multivesicular body protein 2A. (222 aa)
SORT1Sortilin. (831 aa)
EVI5Ecotropic viral integration site 5. (697 aa)
BTBD8BTB domain containing 8. (1356 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (14%) [HD]