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PNPLA3 PNPLA3 PNPLA5 PNPLA5 APOB APOB MGLL MGLL LIPI LIPI GPIHBP1 GPIHBP1 CPS1 CPS1 PNPLA1 PNPLA1 PLB1 PLB1 PNPLA2 PNPLA2 LIPC LIPC LIPH LIPH PNPLA4 PNPLA4 DDHD2 DDHD2 LPL LPL LIPG LIPG LIPE LIPE APOA5 APOA5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PNPLA3Patatin like phospholipase domain containing 3. (437 aa)
PNPLA5Patatin like phospholipase domain containing 5. (429 aa)
APOBApolipoprotein B. (4555 aa)
MGLLMonoglyceride lipase. (339 aa)
LIPILipase I. (415 aa)
GPIHBP1Glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1. (210 aa)
CPS1Carbamoyl-phosphate synthase 1. (1504 aa)
PNPLA1Patatin like phospholipase domain containing 1. (532 aa)
PLB1Phospholipase B1. (1464 aa)
PNPLA2Patatin like phospholipase domain containing 2. (515 aa)
LIPCLipase C, hepatic type. (499 aa)
LIPHLipase H. (451 aa)
PNPLA4Patatin like phospholipase domain containing 4. (248 aa)
DDHD2DDHD domain containing 2. (575 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
LIPGLipase G, endothelial type. (500 aa)
LIPELipase E, hormone sensitive type. (1069 aa)
APOA5Apolipoprotein A5. (366 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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