STRINGSTRING
COL2A1 COL2A1 PDGFB PDGFB IL9R IL9R PXDN PXDN COL6A1 COL6A1 THBS1 THBS1 NTRK2 NTRK2 IL2RB IL2RB LTBP3 LTBP3 FLT4 FLT4 NRROS NRROS CHRDL1 CHRDL1 INSR INSR TRIM16 TRIM16 FGFR4 FGFR4 IGFBP5 IGFBP5 IGFBP2 IGFBP2 TGFBR2 TGFBR2 NRP2 NRP2 SRPX2 SRPX2 IGFBPL1 IGFBPL1 TGFBR1 TGFBR1 SEC61B SEC61B ENSCSAP00000007371 ENSCSAP00000007371 RPS2 RPS2 IGFALS IGFALS NRP1 NRP1 IL2RG IL2RG LTBP1 LTBP1 PDGFRB PDGFRB CRIM1 CRIM1 CD36 CD36 TGFB3 TGFB3 ENSCSAP00000008428 ENSCSAP00000008428 LTBP2 LTBP2 IGF2R IGF2R COL3A1 COL3A1 ITGAV ITGAV WFIKKN1 WFIKKN1 COL1A2 COL1A2 RHBDF1 RHBDF1 IL2RA IL2RA FSTL4 FSTL4 ENG ENG CD109 CD109 HYAL2 HYAL2 SPINT3 SPINT3 ACVR2B ACVR2B ENSCSAP00000010642 ENSCSAP00000010642 SCN5A SCN5A FGFR2 FGFR2 ITGA6 ITGA6 GHRHR GHRHR LRP2 LRP2 FGFR1 FGFR1 ENSCSAP00000011551 ENSCSAP00000011551 FGFRL1 FGFRL1 COL5A1 COL5A1 FGFR3 FGFR3 IGFBP1 IGFBP1 IGFBP3 IGFBP3 ACVR1 ACVR1 ACVR1C ACVR1C EGFR EGFR ACVR2A ACVR2A IL6ST IL6ST CCN2 CCN2 IL1RN IL1RN IL36RN IL36RN PCSK6 PCSK6 KLB KLB IGF1R IGF1R OSMR OSMR LIFR LIFR FURIN FURIN IL1R1 IL1R1 IL1R2 IL1R2 NKD2 NKD2 COL4A1 COL4A1 PDGFA PDGFA TWSG1 TWSG1 KL KL FLT1 FLT1 FLT3 FLT3 AXL AXL CEP57 CEP57 IGFBP4 IGFBP4 IL10RA IL10RA NGFR NGFR NTRK1 NTRK1 SHC1 SHC1 IL6R IL6R HAX1 HAX1 S100A13 S100A13 NLRP7 NLRP7 SORT1 SORT1 TGFBR3 TGFBR3 CCN1 CCN1 EPHA8 EPHA8 EPHA2 EPHA2 TSKU TSKU ENSCSAP00000017473 ENSCSAP00000017473 ENSCSAP00000017574 ENSCSAP00000017574 ENSCSAP00000017975 ENSCSAP00000017975 FGFBP3 FGFBP3 ENSCSAP00000017991 ENSCSAP00000017991 SDCBP SDCBP ENSCSAP00000018239 ENSCSAP00000018239 ENSCSAP00000018303 ENSCSAP00000018303 ENSCSAP00000018320 ENSCSAP00000018320 ENSCSAP00000018494 ENSCSAP00000018494 ENSCSAP00000019116 ENSCSAP00000019116 FGFBP1 FGFBP1 HTRA1 HTRA1 CXCL13 CXCL13 GLG1 GLG1 LRRC32 LRRC32 ENSCSAP00000000085 ENSCSAP00000000085 LTBP4 LTBP4 KDR KDR IGFBP7 IGFBP7 RHBDF2 RHBDF2 COL1A1 COL1A1 ERBB3 ERBB3 WFIKKN2 WFIKKN2 API5 API5 KAZALD1 KAZALD1 IGFBP6 IGFBP6 ACVRL1 ACVRL1 GPC1 GPC1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
COL2A1Collagen type II alpha 1 chain. (1488 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
IL9RInterleukin 9 receptor. (418 aa)
PXDNPeroxidasin. (1479 aa)
COL6A1Uncharacterized protein. (1003 aa)
THBS1Thrombospondin 1. (1170 aa)
NTRK2Neurotrophic receptor tyrosine kinase 2. (477 aa)
IL2RBInterleukin 2 receptor subunit beta. (551 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1298 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1361 aa)
NRROSNegative regulator of reactive oxygen species. (732 aa)
CHRDL1Chordin like 1. (458 aa)
INSRTyrosine-protein kinase receptor. (1385 aa)
TRIM16Uncharacterized protein. (557 aa)
FGFR4Fibroblast growth factor receptor. (806 aa)
IGFBP5Insulin like growth factor binding protein 5. (272 aa)
IGFBP2Insulin like growth factor binding protein 2. (325 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (567 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (901 aa)
SRPX2Sushi repeat containing protein X-linked 2. (427 aa)
IGFBPL1Insulin like growth factor binding protein like 1. (273 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (434 aa)
SEC61BProtein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (96 aa)
ENSCSAP00000007371S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (287 aa)
RPS2S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
IGFALSInsulin like growth factor binding protein acid labile subunit. (605 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
IL2RGFibronectin type-III domain-containing protein. (369 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1724 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1106 aa)
CRIM1Cysteine rich transmembrane BMP regulator 1. (1036 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
ENSCSAP00000008428S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
LTBP2Latent transforming growth factor beta binding protein 2. (1824 aa)
IGF2RInsulin like growth factor 2 receptor. (2491 aa)
COL3A1Collagen type III alpha 1 chain. (878 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1048 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (548 aa)
COL1A2Collagen type I alpha 2 chain. (1274 aa)
RHBDF1Rhomboid 5 homolog 1. (855 aa)
IL2RAInterleukin 2 receptor subunit alpha. (274 aa)
FSTL4Follistatin like 4. (745 aa)
ENGEndoglin. (658 aa)
CD109CD109 molecule. (1201 aa)
HYAL2Hyaluronidase. (473 aa)
SPINT3Serine peptidase inhibitor, Kunitz type 3. (89 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (354 aa)
ENSCSAP00000010642Uncharacterized protein. (241 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1881 aa)
FGFR2Fibroblast growth factor receptor. (840 aa)
ITGA6Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1073 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (393 aa)
LRP2LDL receptor related protein 2. (3861 aa)
FGFR1Fibroblast growth factor receptor. (830 aa)
ENSCSAP00000011551Uncharacterized protein. (357 aa)
FGFRL1Fibroblast growth factor receptor like 1. (474 aa)
COL5A1Collagen type V alpha 1 chain. (1641 aa)
FGFR3Fibroblast growth factor receptor. (806 aa)
IGFBP1Insulin like growth factor binding protein 1. (281 aa)
IGFBP3Insulin like growth factor binding protein 3. (291 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
ACVR1CReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (443 aa)
EGFRReceptor protein-tyrosine kinase. (1210 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
IL6STInterleukin 6 signal transducer. (928 aa)
CCN2Cellular communication network factor 2. (349 aa)
IL1RNInterleukin-1. (177 aa)
IL36RNInterleukin-1. (155 aa)
PCSK6Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (839 aa)
KLBKlotho beta. (907 aa)
IGF1RTyrosine-protein kinase receptor. (1064 aa)
OSMROncostatin M receptor. (977 aa)
LIFRLIF receptor subunit alpha. (1097 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (794 aa)
IL1R1Interleukin 1 receptor type 1. (569 aa)
IL1R2Interleukin 1 receptor type 2. (418 aa)
NKD2NKD inhibitor of WNT signaling pathway 2. (454 aa)
COL4A1Collagen type IV alpha 1 chain. (1669 aa)
PDGFAPlatelet derived growth factor subunit A; Belongs to the PDGF/VEGF growth factor family. (196 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
KLKlotho. (1010 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1338 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (974 aa)
AXLAXL receptor tyrosine kinase. (894 aa)
CEP57Centrosomal protein 57. (499 aa)
IGFBP4Insulin like growth factor binding protein 4. (258 aa)
IL10RAInterleukin 10 receptor subunit alpha. (578 aa)
NGFRNerve growth factor receptor. (427 aa)
NTRK1Tyrosine-protein kinase receptor. (796 aa)
SHC1SHC adaptor protein 1. (474 aa)
IL6RInterleukin 6 receptor. (443 aa)
HAX1HCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (279 aa)
S100A13S100 calcium binding protein A13; Belongs to the S-100 family. (98 aa)
NLRP7NLR family pyrin domain containing 7. (861 aa)
SORT1Sortilin. (831 aa)
TGFBR3Transforming growth factor beta receptor 3. (860 aa)
CCN1Cellular communication network factor 1. (381 aa)
EPHA8EPH receptor A8. (1006 aa)
EPHA2EPH receptor A2. (1033 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
ENSCSAP00000017473S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
ENSCSAP00000017574S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
ENSCSAP00000017975S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
FGFBP3Fibroblast growth factor binding protein 3. (260 aa)
ENSCSAP00000017991S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (291 aa)
SDCBPUncharacterized protein. (293 aa)
ENSCSAP00000018239S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (277 aa)
ENSCSAP00000018303S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (291 aa)
ENSCSAP00000018320S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (289 aa)
ENSCSAP00000018494S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (289 aa)
ENSCSAP00000019116S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (293 aa)
FGFBP1Fibroblast growth factor binding protein 1. (234 aa)
HTRA1HtrA serine peptidase 1. (524 aa)
CXCL13C-X-C motif chemokine. (109 aa)
GLG1Golgi glycoprotein 1. (1051 aa)
LRRC32Leucine rich repeat containing 32. (662 aa)
ENSCSAP00000000085S5 DRBM domain-containing protein; Belongs to the universal ribosomal protein uS5 family. (283 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1557 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1356 aa)
IGFBP7Insulin like growth factor binding protein 7. (282 aa)
RHBDF2Rhomboid 5 homolog 2. (856 aa)
COL1A1Collagen type I alpha 1 chain. (1464 aa)
ERBB3Erb-b2 receptor tyrosine kinase 3. (1342 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (576 aa)
API5Apoptosis inhibitor 5. (524 aa)
KAZALD1Kazal type serine peptidase inhibitor domain 1. (302 aa)
IGFBP6Insulin like growth factor binding protein 6. (239 aa)
ACVRL1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (503 aa)
GPC1Glypican 1; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (558 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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