STRINGSTRING
LBX1 LBX1 MNX1 MNX1 PTCH1 PTCH1 GIGYF2 GIGYF2 SHH SHH GBX1 GBX1 DLL4 DLL4 SCYL1 SCYL1 ABT1 ABT1 GATA2 GATA2 DMRT3 DMRT3 VLDLR VLDLR NKX2-2 NKX2-2 SCYL3 SCYL3 RELN RELN ZC4H2 ZC4H2 LHX4 LHX4 HOXD10 HOXD10 ISL2 ISL2 TBX20 TBX20 MDGA2 MDGA2 GLI3 GLI3 DCTN1 DCTN1 LHX3 LHX3 GLI2 GLI2 SOX4 SOX4 ASCL1 ASCL1 OLIG2 OLIG2 OLIG3 OLIG3 LRP8 LRP8 LMO4 LMO4 TCTN1 TCTN1 FOXN4 FOXN4 DYNC2H1 DYNC2H1 VSTM5 VSTM5 CLN8 CLN8 ISL1 ISL1 PHOX2A PHOX2A DBX1 DBX1 PAX6 PAX6 SUFU SUFU HOXC10 HOXC10
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LBX1Ladybird homeobox 1. (281 aa)
MNX1Motor neuron and pancreas homeobox 1. (401 aa)
PTCH1Patched 1. (1452 aa)
GIGYF2GRB10 interacting GYF protein 2. (1232 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
GBX1Gastrulation brain homeobox 1. (434 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (663 aa)
SCYL1SCY1 like pseudokinase 1. (808 aa)
ABT1Activator of basal transcription 1. (276 aa)
GATA2GATA binding protein 2. (397 aa)
DMRT3Doublesex and mab-3 related transcription factor 3. (472 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
NKX2-2NK2 homeobox 2. (273 aa)
SCYL3SCY1 like pseudokinase 3. (742 aa)
RELNReelin. (3427 aa)
ZC4H2Zinc finger C4H2-type containing. (224 aa)
LHX4LIM homeobox 4. (390 aa)
HOXD10Homeobox D10. (340 aa)
ISL2ISL LIM homeobox 2. (359 aa)
TBX20T-box transcription factor 20. (447 aa)
MDGA2MAM domain containing glycosylphosphatidylinositol anchor 2. (932 aa)
GLI3GLI family zinc finger 3. (1459 aa)
DCTN1CAP-Gly domain-containing protein. (1433 aa)
LHX3LIM homeobox 3. (402 aa)
GLI2GLI family zinc finger 2. (1554 aa)
SOX4Transcription factor SOX. (475 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (239 aa)
OLIG2Oligodendrocyte transcription factor 2. (323 aa)
OLIG3Oligodendrocyte transcription factor 3. (273 aa)
LRP8LDL receptor related protein 8. (1002 aa)
LMO4LIM domain only 4. (165 aa)
TCTN1Tectonic family member 1. (587 aa)
FOXN4Forkhead box N4. (517 aa)
DYNC2H1Dynein cytoplasmic 2 heavy chain 1. (4311 aa)
VSTM5V-set and transmembrane domain containing 5. (199 aa)
CLN8CLN8 transmembrane ER and ERGIC protein. (286 aa)
ISL1ISL LIM homeobox 1. (349 aa)
PHOX2APaired like homeobox 2A. (284 aa)
DBX1Developing brain homeobox 1. (344 aa)
PAX6Paired box 6. (436 aa)
SUFUSuppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...] (484 aa)
HOXC10Homeobox C10. (342 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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