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| | ENSCSAP00000018652 | annotation not available (156 aa) |
| | ENSCSAP00000018628 | Ribosomal_L23eN domain-containing protein. (154 aa) |
| | EIF3G-2 | Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (320 aa) |
| | ENSCSAP00000018400 | Uncharacterized protein. (264 aa) |
| | ENSCSAP00000018382 | Ribosomal_L6e_N domain-containing protein. (288 aa) |
| | RPSA | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa) |
| | SNRPE | Small nuclear ribonucleoprotein E; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development. (92 aa) |
| | ENSCSAP00000018249 | 60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family. (288 aa) |
| | ENSCSAP00000018171 | HIT-type domain-containing protein. (155 aa) |
| | EIF3J | Eukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (258 aa) |
| | ENSCSAP00000018129 | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa) |
| | RRS1 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa) |
| | DDX28 | DEAD-box helicase 28. (546 aa) |
| | ENSCSAP00000017968 | HIT-type domain-containing protein. (155 aa) |
| | RPL24-2 | TRASH domain-containing protein. (157 aa) |
| | ENSCSAP00000017850 | Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (156 aa) |
| | ENSCSAP00000017835 | Ribosomal_L18_c domain-containing protein. (296 aa) |
| | RPS28 | Uncharacterized protein. (68 aa) |
| | SF3B5 | Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa) |
| | RPL5 | Ribosomal_L18_c domain-containing protein. (297 aa) |
| | ENSCSAP00000017732 | Ribosomal_L23eN domain-containing protein. (156 aa) |
| | LOC103230486 | 40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteri [...] (295 aa) |
| | ENSCSAP00000017685 | Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (156 aa) |
| | ENSCSAP00000017627 | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa) |
| | MRPL20 | Uncharacterized protein; Belongs to the bacterial ribosomal protein bL20 family. (149 aa) |
| | MRTO4 | Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa) |
| | SRSF10 | Serine and arginine rich splicing factor 10. (167 aa) |
| | EIF3I | Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (325 aa) |
| | AGO4 | Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (861 aa) |
| | AGO1 | Argonaute RISC component 1; Belongs to the argonaute family. (857 aa) |
| | AGO3 | Protein argonaute-3; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. (860 aa) |
| | SNIP1 | Smad nuclear interacting protein 1. (396 aa) |
| | SF3A3 | Splicing factor 3a subunit 3. (476 aa) |
| | ZNHIT6 | Zinc finger HIT-type containing 6. (470 aa) |
| | ENSCSAP00000016553 | Ribosomal_L18_c domain-containing protein. (247 aa) |
| | PTBP2 | Polypyrimidine tract binding protein 2. (531 aa) |
| | WDR77 | WD repeat domain 77. (342 aa) |
| | DDX20 | DEAD-box helicase 20. (827 aa) |
| | RPS5 | Ribosomal protein S5; Belongs to the universal ribosomal protein uS7 family. (204 aa) |
| | CELF3 | CUGBP Elav-like family member 3. (389 aa) |
| | ENSCSAP00000016189 | RL10P_insert domain-containing protein. (307 aa) |
| | SFSWAP | Splicing factor SWAP. (948 aa) |
| | PRPF31 | Pre-mRNA processing factor 31. (499 aa) |
| | ADAR | Adenosine deaminase RNA specific. (931 aa) |
| | KHDC4 | KH domain containing 4, pre-mRNA splicing factor. (614 aa) |
| | DENR | Density-regulated protein; Belongs to the DENR family. (152 aa) |
| | SRSF9 | Serine and arginine rich splicing factor 9. (221 aa) |
| | RPLP0 | 60S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (279 aa) |
| | ENSCSAP00000015556 | Ribosomal_L6e_N domain-containing protein. (219 aa) |
| | PIH1D1 | PIH1 domain containing 1. (290 aa) |
| | BUD13 | BUD13 homolog. (619 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa) |
| | ENSCSAP00000015254 | Ribosomal_L23eN domain-containing protein. (156 aa) |
| | PIH1D2 | PIH1 domain containing 2. (315 aa) |
| | SART3 | Spliceosome associated factor 3, U4/U6 recycling protein. (963 aa) |
| | NOP53 | Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (478 aa) |
| | C12orf45 | Chromosome 12 open reading frame 45. (186 aa) |
| | SNRPD2 | Small nuclear ribonucleoprotein Sm D2; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. (118 aa) |
| | NAF1 | Nuclear assembly factor 1 ribonucleoprotein. (497 aa) |
| | SNRPF | Small nuclear ribonucleoprotein polypeptide F. (123 aa) |
| | MCTS1 | Malignant T-cell-amplified sequence. (181 aa) |
| | TXNL4A | Thioredoxin like 4A. (103 aa) |
| | EIF4H | Eukaryotic translation initiation factor 4H. (228 aa) |
| | SF3B4 | Splicing factor 3b subunit 4. (424 aa) |
| | ENSCSAP00000014076 | JAB_MPN domain-containing protein; Belongs to the eIF-3 subunit F family. (323 aa) |
| | ENSCSAP00000013960 | Uncharacterized protein. (160 aa) |
| | ENSCSAP00000013957 | RRM domain-containing protein. (144 aa) |
| | NUFIP1 | Nuclear FMR1 interacting protein 1. (495 aa) |
| | SNRPD1 | Small nuclear ribonucleoprotein Sm D1; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through non-specific electrostatic contacts with RNA. (119 aa) |
| | EIF3B | Eukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (811 aa) |
| | MRM2 | Mitochondrial rRNA methyltransferase 2. (255 aa) |
| | SNRNP200 | Small nuclear ribonucleoprotein U5 subunit 200. (2136 aa) |
| | SRSF12 | Serine and arginine rich splicing factor 12. (262 aa) |
| | MDN1 | Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5014 aa) |
| | ENSCSAP00000013317 | Uncharacterized protein. (566 aa) |
| | MRPS11 | Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (194 aa) |
| | ENSCSAP00000012922 | Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (242 aa) |
| | POLR2D | RNA polymerase II subunit D. (142 aa) |
| | DHX29 | ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1368 aa) |
| | USP39 | Ubiquitin specific peptidase 39. (565 aa) |
| | PRMT5 | Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (637 aa) |
| | DHX30 | DExH-box helicase 30. (1169 aa) |
| | GCFC2 | GC-rich sequence DNA-binding factor 2. (788 aa) |
| | ENSCSAP00000011744 | Tudor domain-containing protein. (294 aa) |
| | ENSCSAP00000011517 | Ribosomal_S7 domain-containing protein. (152 aa) |
| | PRPF39 | Pre-mRNA processing factor 39. (548 aa) |
| | ENSCSAP00000011248 | Small nuclear ribonucleoprotein G; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. (76 aa) |
| | USP4 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (908 aa) |
| | ENSCSAP00000011163 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (136 aa) |
| | ENSCSAP00000011123 | Uncharacterized protein. (164 aa) |
| | EIF2D | Eukaryotic translation initiation factor 2D. (584 aa) |
| | SETX | Senataxin. (2679 aa) |
| | ZRSR2 | Zinc finger CCCH-type, RNA binding motif and serine/arginine rich 2. (482 aa) |
| | PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4131 aa) |
| | TGS1 | Trimethylguanosine synthase 1. (798 aa) |
| | ENSCSAP00000010621 | Uncharacterized protein. (167 aa) |
| | EIF3C | Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (913 aa) |
| | CPSF7 | Cleavage and polyadenylation specific factor 7. (462 aa) |
| | AHNAK | AHNAK nucleoprotein. (4337 aa) |
| | SCAF11 | SR-related CTD associated factor 11. (1464 aa) |
| | SRPK3 | SRSF protein kinase 3. (568 aa) |
| | EIF3L | Eukaryotic translation initiation factor 3 subunit L. (301 aa) |
| | ERAL1 | Era like 12S mitochondrial rRNA chaperone 1. (437 aa) |
| | RPL23A | Ribosomal_L23eN domain-containing protein; Belongs to the universal ribosomal protein uL23 family. (156 aa) |
| | SF1 | Splicing factor 1. (548 aa) |
| | CXorf66 | Chromosome X open reading frame 66. (361 aa) |
| | EIF3G | Eukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (320 aa) |
| | FAU | 40S ribosomal protein S30; Belongs to the eukaryotic ribosomal protein eS30 family. (133 aa) |
| | ENSCSAP00000004154 | RRM domain-containing protein. (600 aa) |
| | EIF3D | Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, a complex required for several steps in the initiation of protein synthesis of a specialized repertoire of mRNAs. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required [...] (544 aa) |
| | PWP2 | Uncharacterized protein. (919 aa) |
| | RBMX2 | RNA binding motif protein X-linked 2. (324 aa) |
| | RBM5 | RNA binding motif protein 5. (815 aa) |
| | ENSCSAP00000010410 | RRM domain-containing protein. (607 aa) |
| | GEMIN4 | Gem nuclear organelle associated protein 4. (1058 aa) |
| | SRSF6 | Serine and arginine rich splicing factor 6. (343 aa) |
| | PRPF8 | Pre-mRNA processing factor 8. (2335 aa) |
| | ENSCSAP00000010012 | 60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family. (291 aa) |
| | CELF6 | Uncharacterized protein. (481 aa) |
| | CDC73 | Cell division cycle 73. (531 aa) |
| | ENSCSAP00000009274 | Ribosomal_L6e_N domain-containing protein. (279 aa) |
| | LUC7L | LUC7 like. (371 aa) |
| | SRSF5 | Serine and arginine rich splicing factor 5. (272 aa) |
| | DHX9 | DExH-box helicase 9. (1126 aa) |
| | GEMIN6 | Gem nuclear organelle associated protein 6. (167 aa) |
| | SF3A2 | Splicing factor 3a subunit 2. (471 aa) |
| | EIF3E | Eukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (445 aa) |
| | C9H10orf126 | Uncharacterized protein. (116 aa) |
| | SNRPB2 | Small nuclear ribonucleoprotein polypeptide B2. (225 aa) |
| | SRPK2 | SRSF protein kinase 2. (702 aa) |
| | RPS14 | Ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family. (151 aa) |
| | SHQ1 | SHQ1, H/ACA ribonucleoprotein assembly factor. (488 aa) |
| | SF3B1 | Splicing factor 3b subunit 1. (1304 aa) |
| | CRNKL1 | Crooked neck pre-mRNA splicing factor 1. (687 aa) |
| | CELF5 | CUGBP Elav-like family member 5. (397 aa) |
| | TRAF7 | TNF receptor associated factor 7. (670 aa) |
| | NCBP1 | Nuclear cap binding protein subunit 1. (790 aa) |
| | SNRPB | Small nuclear ribonucleoprotein-associated protein. (231 aa) |
| | GEMIN5 | Gem nuclear organelle associated protein 5. (1512 aa) |
| | SNRPD3 | Small nuclear ribonucleoprotein Sm D3; Plays role in pre-mRNA splicing as core component of the SMN- Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone pre-mRNA 3'-end processing. (126 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1920 aa) |
| | YJU2 | YJU2 splicing factor homolog. (325 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | NOP2 | SAM_MT_RSMB_NOP domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (816 aa) |
| | SLU7 | SLU7 homolog, splicing factor. (490 aa) |
| | FASTKD2 | FAST kinase domains 2. (694 aa) |
| | ENSCSAP00000006155 | Ribosomal_S7 domain-containing protein. (199 aa) |
| | SNRPC | U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (178 aa) |
| | AGO2 | Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (904 aa) |
| | SF3A1 | Splicing factor 3a subunit 1. (793 aa) |
| | PSIP1 | PC4 and SFRS1 interacting protein 1. (530 aa) |
| | XRCC5 | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (732 aa) |
| | LSM2 | U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa) |
| | ISY1 | Uncharacterized protein. (285 aa) |
| | BOP1 | Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (745 aa) |
| | RPL24 | Ribosomal protein L24. (177 aa) |
| | PRPF19 | Pre-mRNA processing factor 19. (504 aa) |
| | CCDC105 | Coiled-coil domain containing 105. (417 aa) |
| | CD2BP2 | CD2 cytoplasmic tail binding protein 2. (341 aa) |
| | ZNHIT3 | HIT-type domain-containing protein. (155 aa) |
| | CLP1 | Polyribonucleotide 5'-hydroxyl-kinase Clp1; Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of double-stranded RNA (dsRNA), single-stranded RNA (ssRNA), double stranded DNA (dsDNA) and double-stranded DNA:RNA hybrids. dsRNA is phosphorylated more efficiently than dsDNA, and the RNA component of a DNA:RNA hybrid is phosphorylated more efficiently than the DNA component. Appears to have roles in both tRNA splicing and mRNA 3'-end formation. Component of the tRNA splicing endonuclease complex. Phosphorylates the 5'-terminus of the tRNA 3'-exon during tRNA splicing; thi [...] (425 aa) |
| | PHF5A | PHD finger protein 5A. (110 aa) |
| | CELF1 | CUGBP Elav-like family member 1. (513 aa) |
| | SNU13 | Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa) |
| | SRSF1 | Uncharacterized protein. (253 aa) |
| | EIF4B | Eukaryotic translation initiation factor 4B. (611 aa) |
| | LUC7L3 | LUC7 like 3 pre-mRNA splicing factor. (472 aa) |
| | TARBP2 | RISC-loading complex subunit TARBP2; Required for formation of the RNA induced silencing complex (RISC). Component of the RISC loading complex (RLC), also known as the micro-RNA (miRNA) loading complex (miRLC), which is composed of DICER1, AGO2 and TARBP2. Within the RLC/miRLC, DICER1 and TARBP2 are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto AGO2. AGO2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from DICER1 and TARBP2. May also play a role in the production of short interfering RNAs (siRNAs) from [...] (366 aa) |
| | LSM4 | U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (139 aa) |
| | EIF3M | Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (374 aa) |
| | YTHDC1 | YTH domain containing 1. (728 aa) |
| | NUDT21 | Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa) |
| | ENSCSAP00000001239 | 40S_SA_C domain-containing protein; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits; Belongs to the universal ribosomal protein uS2 family. (292 aa) |
| | EIF3A | Eukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre- initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termi [...] (1225 aa) |
| | MRPS7 | Mitochondrial ribosomal protein S7. (242 aa) |
| | EIF3F | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (361 aa) |
| | CPSF6 | Cleavage and polyadenylation specific factor 6. (588 aa) |
| | PRMT7 | Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (698 aa) |
| | EIF3K | Eukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF- 2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] (218 aa) |
| | CLNS1A | Chloride nucleotide-sensitive channel 1A. (237 aa) |
| | NOL3 | Nucleolar protein 3. (265 aa) |
| | SART1 | Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (800 aa) |
| | GEMIN7 | Gem nuclear organelle associated protein 7. (131 aa) |
| | ENSCSAP00000018983 | Uncharacterized protein; Belongs to the bacterial ribosomal protein bL20 family. (149 aa) |
| | GEMIN8 | Uncharacterized protein. (242 aa) |
| | ENSCSAP00000018913 | 60S ribosomal protein L6; Belongs to the eukaryotic ribosomal protein eL6 family. (288 aa) |
| | ZNHIT2 | Zinc finger HIT-type containing 2. (404 aa) |
| | STRAP | Serine/threonine kinase receptor associated protein. (350 aa) |
| | SF3B2 | Splicing factor 3b subunit 2. (895 aa) |
| | ABT1 | Activator of basal transcription 1. (276 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | DDX39B | DExD-box helicase 39B. (425 aa) |
| | LUC7L2 | LUC7 like 2, pre-mRNA splicing factor. (392 aa) |
| | SF3B6 | Splicing factor 3b subunit 6. (125 aa) |
| | XAB2 | XPA binding protein 2. (855 aa) |
