(59 nodes) Cholesterol transport network (Chlorocebus sabaeus)

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	ABCA5	ATP binding cassette subfamily A member 5. (1642 aa)
	APOA2	Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism. (100 aa)
	ABCG4	ATP binding cassette subfamily G member 4. (646 aa)
	HNF1A	HNF1 homeobox A. (632 aa)
	SCARB1	Scavenger receptor class B member 1; Belongs to the CD36 family. (470 aa)
	SCP2	Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
	STX12	Syntaxin 12; Belongs to the syntaxin family. (276 aa)
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1. (320 aa)
	TSKU	Tsukushi, small leucine rich proteoglycan. (353 aa)
	LIMA1	LIM domain and actin binding 1. (760 aa)
	SOAT2	O-acyltransferase. (528 aa)
	ENSCSAP00000001494	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
	LIPG	Lipase G, endothelial type. (500 aa)
	RELCH	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1216 aa)
	APOE	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
	APOC2	Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. Belongs to the apolipoprotein C2 family. (101 aa)
	APOA5	Apolipoprotein A5. (366 aa)
	STARD3	StAR related lipid transfer domain containing 3. (445 aa)
	ENSCSAP00000001489	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (567 aa)
	ENSCSAP00000001481	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (532 aa)
	CETP	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (493 aa)
	VPS4A	Uncharacterized protein; Belongs to the AAA ATPase family. (437 aa)
	SYT7	Synaptotagmin 7. (611 aa)
	LDLR	Low density lipoprotein receptor. (767 aa)
	APOB	Apolipoprotein B. (4555 aa)
	ABCG1	ATP binding cassette subfamily G member 1. (666 aa)
	LRP6	Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1613 aa)
	ABCA12	ATP binding cassette subfamily A member 12. (2571 aa)
	TPCN2	Two pore segment channel 2. (752 aa)
	OSBPL5	Oxysterol-binding protein; Belongs to the OSBP family. (846 aa)
	ARV1	ARV1 homolog, fatty acid homeostasis modulator. (271 aa)
	CFTR	CFTR_R domain-containing protein. (289 aa)
	ARL8B	ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (239 aa)
	TSPO2	Translocator protein 2. (170 aa)
	ABCA1	ATP binding cassette subfamily A member 1. (2261 aa)
	CD36	CD36 molecule; Belongs to the CD36 family. (473 aa)
	LIPC	Lipase C, hepatic type. (499 aa)
	SOAT1	O-acyltransferase. (556 aa)
	ABCA7	ATP binding cassette subfamily A member 7. (2149 aa)
	PIP4K2A	Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha. (406 aa)
	NPC2	NPC intracellular cholesterol transporter 2. (151 aa)
	ABCG5	ATP binding cassette subfamily G member 5. (651 aa)
	ABCG8	ATP binding cassette subfamily G member 8. (673 aa)
	SERAC1	Serine active site containing 1. (654 aa)
	ARL8A	ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (186 aa)
	STARD4	StAR related lipid transfer domain containing 4. (205 aa)
	CEL	Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (668 aa)
	STARD3NL	STARD3 N-terminal like. (234 aa)
	STARD5	StAR related lipid transfer domain containing 5. (213 aa)
	STAR	Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (285 aa)
	NPC1L1	NPC1 like intracellular cholesterol transporter 1. (1364 aa)
	OSBPL2	Oxysterol-binding protein; Belongs to the OSBP family. (480 aa)
	CLU	Clusterin; Belongs to the clusterin family. (501 aa)
	ENSCSAP00000012530	Spatacsin_C domain-containing protein. (308 aa)
	MSR1	Macrophage scavenger receptor 1. (451 aa)
	NPC1	NPC intracellular cholesterol transporter 1. (1278 aa)
	OSBP	Oxysterol-binding protein; Belongs to the OSBP family. (805 aa)
	ABCA10	ABC transporter domain-containing protein. (830 aa)
	ABCA8	ATP binding cassette subfamily A member 8. (1623 aa)

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABCA1	ABCG1	ENSCSAP00000007500	ENSCSAP00000004402	ATP binding cassette subfamily A member 1.	ATP binding cassette subfamily G member 1.	0.470
ABCA1	APOA2	ENSCSAP00000007500	ENSCSAP00000015372	ATP binding cassette subfamily A member 1.	Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.	0.727
ABCA1	APOB	ENSCSAP00000007500	ENSCSAP00000004392	ATP binding cassette subfamily A member 1.	Apolipoprotein B.	0.747
ABCA1	APOE	ENSCSAP00000007500	ENSCSAP00000014799	ATP binding cassette subfamily A member 1.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.821
ABCA1	CD36	ENSCSAP00000007500	ENSCSAP00000008090	ATP binding cassette subfamily A member 1.	CD36 molecule; Belongs to the CD36 family.	0.622
ABCA1	CETP	ENSCSAP00000007500	ENSCSAP00000001280	ATP binding cassette subfamily A member 1.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.771
ABCA1	LIPC	ENSCSAP00000007500	ENSCSAP00000008157	ATP binding cassette subfamily A member 1.	Lipase C, hepatic type.	0.640
ABCA1	LIPG	ENSCSAP00000007500	ENSCSAP00000014049	ATP binding cassette subfamily A member 1.	Lipase G, endothelial type.	0.537
ABCA1	NPC1	ENSCSAP00000007500	ENSCSAP00000013710	ATP binding cassette subfamily A member 1.	NPC intracellular cholesterol transporter 1.	0.646
ABCA1	NPC1L1	ENSCSAP00000007500	ENSCSAP00000011693	ATP binding cassette subfamily A member 1.	NPC1 like intracellular cholesterol transporter 1.	0.647
ABCA1	SCARB1	ENSCSAP00000007500	ENSCSAP00000016048	ATP binding cassette subfamily A member 1.	Scavenger receptor class B member 1; Belongs to the CD36 family.	0.643
ABCA1	SOAT1	ENSCSAP00000007500	ENSCSAP00000008289	ATP binding cassette subfamily A member 1.	O-acyltransferase.	0.408
ABCA7	APOE	ENSCSAP00000008548	ENSCSAP00000014799	ATP binding cassette subfamily A member 7.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.545
ABCA7	CLU	ENSCSAP00000008548	ENSCSAP00000012055	ATP binding cassette subfamily A member 7.	Clusterin; Belongs to the clusterin family.	0.704
ABCG1	ABCA1	ENSCSAP00000004402	ENSCSAP00000007500	ATP binding cassette subfamily G member 1.	ATP binding cassette subfamily A member 1.	0.470
ABCG1	ABCG5	ENSCSAP00000004402	ENSCSAP00000009103	ATP binding cassette subfamily G member 1.	ATP binding cassette subfamily G member 5.	0.826
ABCG1	APOA2	ENSCSAP00000004402	ENSCSAP00000015372	ATP binding cassette subfamily G member 1.	Truncated apolipoprotein A-II; May stabilize HDL (high density lipoprotein) structure by its association with lipids, and affect the HDL metabolism.	0.642
ABCG1	APOB	ENSCSAP00000004402	ENSCSAP00000004392	ATP binding cassette subfamily G member 1.	Apolipoprotein B.	0.631
ABCG1	APOE	ENSCSAP00000004402	ENSCSAP00000014799	ATP binding cassette subfamily G member 1.	Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...]	0.753
ABCG1	CETP	ENSCSAP00000004402	ENSCSAP00000001280	ATP binding cassette subfamily G member 1.	Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.	0.685

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