STRINGSTRING
WDR5 WDR5 SUPT6H SUPT6H DNMT1 DNMT1 SIRT1 SIRT1 JARID2 JARID2 KDM4C KDM4C FH FH PHF1 PHF1 KDM4B KDM4B AASS AASS PAX5 PAX5 SMARCB1 SMARCB1 DNMT3B DNMT3B EZHIP EZHIP MACROH2A1 MACROH2A1 BCOR BCOR KDM3A KDM3A BRCA1 BRCA1 MLLT6 MLLT6 PIH1D1 PIH1D1 MTF2 MTF2 KDM4A KDM4A KDM1A KDM1A PRMT6 PRMT6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WDR5WD repeat domain 5. (334 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1580 aa)
DNMT1DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1616 aa)
SIRT1Sirtuin 1. (743 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1246 aa)
KDM4CLysine demethylase 4C. (1090 aa)
FHFumarate hydratase. (510 aa)
PHF1PHD finger protein 1. (567 aa)
KDM4BLysine demethylase 4B. (1130 aa)
AASSAminoadipate-semialdehyde synthase. (925 aa)
PAX5Paired box 5. (391 aa)
SMARCB1SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (385 aa)
DNMT3BDNA methyltransferase 3 beta; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (856 aa)
EZHIPEZH inhibitory protein. (504 aa)
MACROH2A1Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (368 aa)
BCORBCL6 corepressor. (1721 aa)
KDM3ALysine demethylase 3A. (1321 aa)
BRCA1Uncharacterized protein. (663 aa)
MLLT6MLLT6, PHD finger containing. (1091 aa)
PIH1D1PIH1 domain containing 1. (290 aa)
MTF2Metal response element binding transcription factor 2. (593 aa)
KDM4AUncharacterized protein. (1018 aa)
KDM1ALysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (872 aa)
PRMT6Protein arginine methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (375 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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