STRINGSTRING
ATF2 ATF2 MSH2 MSH2 TIPIN TIPIN EME2 EME2 NEK11 NEK11 FANCD2 FANCD2 CHEK2 CHEK2 ENSCSAP00000006204 ENSCSAP00000006204 XPC XPC HUS1 HUS1 RAD9A RAD9A ENSCSAP00000017472 ENSCSAP00000017472 RAD9B RAD9B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (933 aa)
TIPINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (307 aa)
EME2Essential meiotic structure-specific endonuclease subunit 2. (383 aa)
NEK11NIMA related kinase 11. (637 aa)
FANCD2Uncharacterized protein. (1458 aa)
CHEK2Protein kinase domain-containing protein. (318 aa)
ENSCSAP00000006204FHA domain-containing protein. (214 aa)
XPCXPC complex subunit, DNA damage recognition and repair factor. (888 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (280 aa)
RAD9ACell cycle checkpoint control protein; Belongs to the rad9 family. (390 aa)
ENSCSAP00000017472ERCC4 domain-containing protein. (551 aa)
RAD9BCell cycle checkpoint control protein; Belongs to the rad9 family. (417 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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