STRINGSTRING
SPIRE2 SPIRE2 HTR3A HTR3A SPIRE1 SPIRE1 SEPTIN6 SEPTIN6 PLCD3 PLCD3 RDX RDX PLK4 PLK4 ICAM2 ICAM2 RAB21 RAB21 PSD PSD SEPTIN2 SEPTIN2 LIMA1 LIMA1 RACGAP1 RACGAP1 CEP55 CEP55 PKN1 PKN1 RAB11FIP4 RAB11FIP4 KATNBL1 KATNBL1 MEN1 MEN1 ZFYVE19 ZFYVE19 MYLK MYLK MYH9 MYH9 NDE1 NDE1 PITPNM1 PITPNM1 SEPTIN12 SEPTIN12 NF2 NF2 DCTN3 DCTN3 MYH10 MYH10 FSD1 FSD1 PLEKHG6 PLEKHG6 ENSCSAP00000007843 ENSCSAP00000007843 SVIL SVIL ANKRD45 ANKRD45 MASTL MASTL RAB11FIP3 RAB11FIP3 ECT2 ECT2 HMCN1 HMCN1 PSD2 PSD2 PSTPIP1 PSTPIP1 ENSCSAP00000010837 ENSCSAP00000010837 HMCN2 HMCN2 SEPTIN7 SEPTIN7 RHOA RHOA RALA RALA STAMBP STAMBP WDR73 WDR73 RHOB RHOB ARF6 ARF6 PKN2 PKN2 RHOC RHOC CIT CIT PPP1CC PPP1CC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SPIRE2Spire type actin nucleation factor 2. (583 aa)
HTR3A5-hydroxytryptamine receptor 3A; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (489 aa)
SPIRE1Spire type actin nucleation factor 1. (656 aa)
SEPTIN6Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (427 aa)
PLCD3Phosphoinositide phospholipase C. (799 aa)
RDXRadixin. (605 aa)
PLK4Polo like kinase 4. (970 aa)
ICAM2Intercellular adhesion molecule 2. (275 aa)
RAB21RAB21, member RAS oncogene family. (223 aa)
PSDPleckstrin and Sec7 domain containing. (1024 aa)
SEPTIN2Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (361 aa)
LIMA1LIM domain and actin binding 1. (760 aa)
RACGAP1Rac GTPase activating protein 1. (634 aa)
CEP55Centrosomal protein 55. (465 aa)
PKN1Protein kinase N1. (944 aa)
RAB11FIP4RAB11 family interacting protein 4. (557 aa)
KATNBL1Katanin regulatory subunit B1 like 1. (304 aa)
MEN1Menin 1. (610 aa)
ZFYVE19Zinc finger FYVE-type containing 19. (395 aa)
MYLKMyosin light chain kinase. (1914 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
NDE1NudE neurodevelopment protein 1. (346 aa)
PITPNM1Phosphatidylinositol transfer protein membrane associated 1. (1244 aa)
SEPTIN12Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (363 aa)
NF2Neurofibromin 2. (590 aa)
DCTN3Dynactin subunit 3. (186 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1976 aa)
FSD1Fibronectin type III and SPRY domain containing 1. (496 aa)
PLEKHG6Pleckstrin homology and RhoGEF domain containing G6. (790 aa)
ENSCSAP00000007843HP domain-containing protein. (97 aa)
SVILHP domain-containing protein. (2123 aa)
ANKRD45ANK_REP_REGION domain-containing protein. (266 aa)
MASTLMicrotubule associated serine/threonine kinase like. (809 aa)
RAB11FIP3RAB11 family interacting protein 3. (491 aa)
ECT2Epithelial cell transforming 2. (914 aa)
HMCN1Hemicentin 1. (5533 aa)
PSD2Pleckstrin and Sec7 domain containing 2. (772 aa)
PSTPIP1Proline-serine-threonine phosphatase interacting protein 1. (416 aa)
ENSCSAP00000010837Uncharacterized protein. (329 aa)
HMCN2Uncharacterized protein. (790 aa)
SEPTIN7Septin 7; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (384 aa)
RHOARas homolog family member A. (193 aa)
RALARAS like proto-oncogene A. (206 aa)
STAMBPSTAM binding protein. (424 aa)
WDR73WD repeat domain 73. (372 aa)
RHOBRas homolog family member B. (196 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
PKN2Protein kinase N2. (983 aa)
RHOCRas homolog family member C. (193 aa)
CITCitron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2068 aa)
PPP1CCSerine/threonine-protein phosphatase. (293 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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