STRINGSTRING
GLI3 GLI3 BMP6 BMP6 SOX6 SOX6 SOX9 SOX9 BMPR1B BMPR1B FGF18 FGF18 GDF5 GDF5 GDF6 GDF6 PKDCC PKDCC RUNX2 RUNX2 SMAD3 SMAD3 HOXA11 HOXA11 HOXD11 HOXD11 SOX5 SOX5 LOXL2 LOXL2 ZNF219 ZNF219 SMAD7 SMAD7 POR POR ZBTB16 ZBTB16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GLI3GLI family zinc finger 3. (1459 aa)
BMP6Bone morphogenetic protein 6. (433 aa)
SOX6SRY-box transcription factor 6. (466 aa)
SOX9SRY-box transcription factor 9. (509 aa)
BMPR1BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (536 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
GDF5Growth differentiation factor 5. (499 aa)
GDF6Growth differentiation factor 6. (455 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (493 aa)
RUNX2Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. (450 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
HOXA11Homeobox A11. (310 aa)
HOXD11Homeobox D11. (338 aa)
SOX5SRY-box transcription factor 5. (763 aa)
LOXL2Lysyl oxidase like 2. (774 aa)
ZNF219Zinc finger protein 219. (722 aa)
SMAD7Mothers against decapentaplegic homolog. (426 aa)
PORNADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.