STRINGSTRING
PLAA PLAA TNFRSF1A TNFRSF1A ALOXE3 ALOXE3 ALOX12B ALOX12B ALOX15B ALOX15B MIF MIF PNPLA8 PNPLA8 CD74 CD74 AWAT1 AWAT1 FAAH2 FAAH2 PTGR1 PTGR1 ABHD6 ABHD6 ALOX12 ALOX12 CYP1B1 CYP1B1 ENSCSAP00000008436 ENSCSAP00000008436 GPX4 GPX4 PTGR2 PTGR2 DECR2 DECR2 ALOX15 ALOX15 ELOVL5 ELOVL5 PTGS2 PTGS2 PLA2G4A PLA2G4A PTGS1 PTGS1 LOC103246731 LOC103246731 ENSCSAP00000010016 ENSCSAP00000010016 AKR1C3 AKR1C3 PTGES2 PTGES2 ACAA1 ACAA1 ACOT8 ACOT8 PTGES PTGES PTGIS PTGIS GPX1 GPX1 ELOVL6 ELOVL6 CYP2U1 CYP2U1 HPGDS HPGDS SCD5 SCD5 ACOX1 ACOX1 ELOVL3 ELOVL3 SCD SCD CYP4F11 CYP4F11 CYP4F12 CYP4F12 CYP4F57 CYP4F57 ENSCSAP00000018834 ENSCSAP00000018834 PRXL2B PRXL2B PDPN PDPN PLA2G2F PLA2G2F EDN2 EDN2 FAAH FAAH ENSCSAP00000016771 ENSCSAP00000016771 CYP4A22 CYP4A22 SCP2 SCP2 CYP2J2 CYP2J2 PLA2G4C PLA2G4C HPGD HPGD CYP2S1 CYP2S1 CYP2A28 CYP2A28 CYP2G2 CYP2G2 CYP2B6 CYP2B6 CYP2A23 CYP2A23 CYP2A24 CYP2A24 ZADH2 ZADH2 DAGLB DAGLB ELOVL4 ELOVL4 EPHX1 EPHX1 PTGDS PTGDS ELOVL7 ELOVL7 ATP6V1B1 ATP6V1B1 ENSCSAP00000002230 ENSCSAP00000002230 CYP4F3 CYP4F3 CYP4F8 CYP4F8 CYP4F23 CYP4F23 CYP2C8 CYP2C8 CYP2C9 CYP2C9 DAGLA DAGLA FADS1 FADS1 FADS2 FADS2 FADS3 FADS3 ELOVL2 ELOVL2 EDN1 EDN1 PLA2G10 PLA2G10 TBXAS1 TBXAS1 PLA2G4F PLA2G4F MGLL MGLL GSTP1 GSTP1 AKR1B1 AKR1B1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PLAAPhospholipase A2 activating protein. (795 aa)
TNFRSF1ATNF receptor superfamily member 1A. (455 aa)
ALOXE3Arachidonate lipoxygenase 3. (714 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (701 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (676 aa)
MIFMacrophage migration inhibitory factor. (115 aa)
PNPLA8Patatin like phospholipase domain containing 8. (782 aa)
CD74CD74 molecule. (294 aa)
AWAT1Acyl-CoA wax alcohol acyltransferase 1. (330 aa)
FAAH2Fatty acid amide hydrolase 2. (532 aa)
PTGR1Prostaglandin reductase 1. (280 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (663 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (542 aa)
ENSCSAP00000008436Uncharacterized protein. (665 aa)
GPX4Uncharacterized protein. (109 aa)
PTGR2Uncharacterized protein. (327 aa)
DECR22,4-dienoyl-CoA reductase 2. (292 aa)
ALOX15Arachidonate 15-lipoxygenase. (610 aa)
ELOVL5Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa)
PTGS2Prostaglandin-endoperoxide synthase 2. (572 aa)
PLA2G4APhospholipase A2. (749 aa)
PTGS1Prostaglandin-endoperoxide synthase 1. (599 aa)
LOC103246731Uncharacterized protein. (741 aa)
ENSCSAP00000010016Aldo_ket_red domain-containing protein. (323 aa)
AKR1C3Aldo-keto reductase family 1 member C3. (326 aa)
PTGES2Prostaglandin E synthase 2; Belongs to the GST superfamily. (377 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (454 aa)
ACOT8Acyl-CoA thioesterase 8. (319 aa)
PTGESProstaglandin E synthase. (145 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (492 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
ELOVL6Elongation of very long chain fatty acids protein. (192 aa)
CYP2U1Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (544 aa)
HPGDSHematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (199 aa)
SCD5Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (344 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (660 aa)
ELOVL3Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa)
SCDStearoyl-CoA desaturase; Belongs to the fatty acid desaturase type 1 family. (359 aa)
CYP4F11Cytochrome P450 family 4 subfamily F member 11; Belongs to the cytochrome P450 family. (520 aa)
CYP4F12Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
CYP4F57Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
ENSCSAP00000018834Aldo_ket_red domain-containing protein. (311 aa)
PRXL2BPeroxiredoxin like 2B. (230 aa)
PDPNPodoplanin. (162 aa)
PLA2G2FPhospholipase A(2). (223 aa)
EDN2Endothelin 2. (178 aa)
FAAHFatty acid amide hydrolase. (580 aa)
ENSCSAP00000016771Uncharacterized protein. (433 aa)
CYP4A22Uncharacterized protein. (455 aa)
SCP2Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
CYP2J2Cytochrome P450 family 2 subfamily J member 2; Belongs to the cytochrome P450 family. (502 aa)
PLA2G4CPhospholipase A2 group IVC. (547 aa)
HPGD15-hydroxyprostaglandin dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (266 aa)
CYP2S1Cytochrome P450 family 2 subfamily S member 1. (512 aa)
CYP2A28Uncharacterized protein; Belongs to the cytochrome P450 family. (497 aa)
CYP2G2Uncharacterized protein; Belongs to the cytochrome P450 family. (496 aa)
CYP2B6Cytochrome P450 family 2 subfamily B member 6; Belongs to the cytochrome P450 family. (491 aa)
CYP2A23Uncharacterized protein; Belongs to the cytochrome P450 family. (498 aa)
CYP2A24Uncharacterized protein; Belongs to the cytochrome P450 family. (494 aa)
ZADH2Zinc binding alcohol dehydrogenase domain containing 2. (382 aa)
DAGLBDiacylglycerol lipase beta. (668 aa)
ELOVL4Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa)
EPHX1Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (455 aa)
PTGDSLipocln_cytosolic_FA-bd_dom domain-containing protein; Belongs to the calycin superfamily. Lipocalin family. (190 aa)
ELOVL7Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa)
ATP6V1B1Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (513 aa)
ENSCSAP00000002230FA_desaturase domain-containing protein. (370 aa)
CYP4F3Uncharacterized protein; Belongs to the cytochrome P450 family. (520 aa)
CYP4F8Cytochrome P450 family 4 subfamily F member 8; Belongs to the cytochrome P450 family. (520 aa)
CYP4F23Uncharacterized protein; Belongs to the cytochrome P450 family. (524 aa)
CYP2C8Cytochrome P450 family 2 subfamily C member 8; Belongs to the cytochrome P450 family. (490 aa)
CYP2C9Uncharacterized protein; Belongs to the cytochrome P450 family. (468 aa)
DAGLADiacylglycerol lipase alpha. (1043 aa)
FADS1Fatty acid desaturase 1. (501 aa)
FADS2Fatty acid desaturase 2. (444 aa)
FADS3Fatty acid desaturase 3. (445 aa)
ELOVL2Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (296 aa)
EDN1Endothelin 1. (211 aa)
PLA2G10Phospholipase A(2). (165 aa)
TBXAS1Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (534 aa)
PLA2G4FPhospholipase A2. (853 aa)
MGLLMonoglyceride lipase. (339 aa)
GSTP1Glutathione S-transferase pi 1. (383 aa)
AKR1B1Aldo-keto reductase family 1 member B. (426 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.