STRINGSTRING
SCARB1 SCARB1 LPL LPL ENSCSAP00000008488 ENSCSAP00000008488 LIPC LIPC ABCA1 ABCA1 TREM2 TREM2 VLDLR VLDLR LRP4 LRP4 LRP1 LRP1 MTTP MTTP LRP8 LRP8 PCSK9 PCSK9 LILRB4 LILRB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SCARB1Scavenger receptor class B member 1; Belongs to the CD36 family. (470 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
ENSCSAP00000008488Uncharacterized protein; Belongs to the peptidase S1 family. (1235 aa)
LIPCLipase C, hepatic type. (499 aa)
ABCA1ATP binding cassette subfamily A member 1. (2261 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (260 aa)
VLDLRVery low density lipoprotein receptor. (873 aa)
LRP4LDL receptor related protein 4. (1669 aa)
LRP1LDL receptor related protein 1. (4544 aa)
MTTPMicrosomal triglyceride transfer protein. (894 aa)
LRP8LDL receptor related protein 8. (1002 aa)
PCSK9Proprotein convertase subtilisin/kexin type 9. (692 aa)
LILRB4Leukocyte immunoglobulin like receptor B4. (448 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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