STRINGSTRING
PDGFB PDGFB KLF15 KLF15 PTPRO PTPRO PODXL PODXL SMO SMO MTSS1 MTSS1 EXT1 EXT1 ENSCSAP00000008056 ENSCSAP00000008056 CD34 CD34 MYO1E MYO1E NPHS2 NPHS2 ASXL1 ASXL1 SIX2 SIX2 JAG1 JAG1 MEF2C MEF2C BMP4 BMP4 LAMB2 LAMB2 EDNRB EDNRB IQGAP1 IQGAP1 GDNF GDNF PROM1 PROM1 NOTCH1 NOTCH1 GREM1 GREM1 GPR4 GPR4 BASP1 BASP1 FOXC2 FOXC2 ENSCSAP00000017880 ENSCSAP00000017880 NOTCH2 NOTCH2 EDNRA EDNRA NPHS1 NPHS1 FOXJ1 FOXJ1 WT1 WT1 SALL1 SALL1 PAX2 PAX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (241 aa)
KLF15Kruppel like factor 15. (416 aa)
PTPROProtein tyrosine phosphatase receptor type O. (1023 aa)
PODXLPodocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Function as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Belongs to the podocalyxin family. (535 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa)
MTSS1MTSS I-BAR domain containing 1. (690 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (420 aa)
ENSCSAP00000008056Uncharacterized protein. (534 aa)
CD34CD34 molecule. (385 aa)
MYO1EMyosin IE; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1108 aa)
NPHS2NPHS2 stomatin family member, podocin. (383 aa)
ASXL1ASXL transcriptional regulator 1. (1541 aa)
SIX2SIX homeobox 2. (290 aa)
JAG1Jagged canonical Notch ligand 1. (1218 aa)
MEF2CMyocyte enhancer factor 2C. (446 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
LAMB2Laminin subunit beta 2. (1798 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (442 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
GDNFGlial cell derived neurotrophic factor. (211 aa)
PROM1Prominin 1. (855 aa)
NOTCH1Notch receptor 1. (2555 aa)
GREM1Gremlin. (184 aa)
GPR4G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
BASP1Brain abundant membrane attached signal protein 1. (227 aa)
FOXC2Forkhead box C2. (501 aa)
ENSCSAP00000017880Uncharacterized protein. (78 aa)
NOTCH2Notch receptor 2. (2471 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
NPHS1NPHS1 adhesion molecule, nephrin. (1242 aa)
FOXJ1Forkhead box J1. (421 aa)
WT1WT1 transcription factor. (320 aa)
SALL1Spalt like transcription factor 1. (1321 aa)
PAX2Paired box 2. (261 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.