108 items (Chlorocebus sabaeus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	MBD3L1	Methyl-CpG binding domain protein 3 like 1. (194 aa)
	NDN	Necdin, MAGE family member. (321 aa)
	H3C11	Histone H3; Belongs to the histone H3 family. (136 aa)
	LOC103221946	Histone H3.1. (136 aa)
	LOC103221946-2	Histone H3.1. (136 aa)
	ARID4B	AT-rich interaction domain 4B. (1314 aa)
	KAT2B	Lysine acetyltransferase 2B. (675 aa)
	BAHD1	Bromo adjacent homology domain containing 1. (780 aa)
	SIRT1	Sirtuin 1. (743 aa)
	DNMT1	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1616 aa)
	CDYL	Chromodomain Y like. (544 aa)
	PHF2	PHD finger protein 2. (980 aa)
	EZH2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (746 aa)
	PPHLN1	Periphilin 1. (458 aa)
	MECP2	Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (479 aa)
	PCGF5	Polycomb group ring finger 5. (256 aa)
	SUZ12	SUZ12 polycomb repressive complex 2 subunit. (739 aa)
	MORC1	CW-type domain-containing protein. (982 aa)
	ENSCSAP00000002484	Uncharacterized protein. (97 aa)
	HELLS	Helicase, lymphoid specific. (713 aa)
	HDAC4	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1088 aa)
	SMARCD1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1. (515 aa)
	CTCF	CCCTC-binding factor. (727 aa)
	PRMT7	Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (698 aa)
	RRP8	Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (456 aa)
	ENSCSAP00000000740	Uncharacterized protein. (88 aa)
	PPM1D	Protein phosphatase, Mg2+/Mn2+ dependent 1D. (605 aa)
	EP300	E1A binding protein p300. (2416 aa)
	KLF2	Kruppel like factor 2. (355 aa)
	YTHDC1	YTH domain containing 1. (728 aa)
	SPTY2D1	SPT2 chromatin protein domain containing 1. (683 aa)
	BAZ2A	Bromodomain adjacent to zinc finger domain 2A. (1909 aa)
	FAM47E	Uncharacterized protein. (268 aa)
	WBP2	WW domain binding protein 2. (261 aa)
	TDG	Thymine DNA glycosylase. (267 aa)
	BRCA1	Uncharacterized protein. (663 aa)
	SMARCA5	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5. (969 aa)
	GSK3A	Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (483 aa)
	HDAC5	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (1155 aa)
	MBD2	Methyl-CpG binding domain protein 2. (262 aa)
	RB1	RB transcriptional corepressor 1. (928 aa)
	SMCHD1	Structural maintenance of chromosomes flexible hinge domain containing 1. (2005 aa)
	METTL3	Methyltransferase like 3; Belongs to the MT-A70-like family. (580 aa)
	RIF1	Replication timing regulatory factor 1. (2465 aa)
	CTBP1	C-terminal binding protein 1; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (421 aa)
	TFAP2C	Transcription factor AP-2 gamma. (251 aa)
	SMYD5	SMYD family member 5. (418 aa)
	PCGF3	Polycomb group ring finger 3. (242 aa)
	GPX1	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (145 aa)
	ZNFX1	AAA_11 domain-containing protein. (812 aa)
	BEND3	BEN domain containing 3. (830 aa)
	HAT1	Histone acetyltransferase type B catalytic subunit; Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. (419 aa)
	FAM172A	Family with sequence similarity 172 member A. (450 aa)
	ZNF335	Zinc finger protein 335. (1346 aa)
	SPHK2	Sphingosine kinase 2. (653 aa)
	MACROH2A2	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (372 aa)
	NRM	Nurim. (262 aa)
	ENSCSAP00000004852	Uncharacterized protein. (195 aa)
	CENPV	Centromere protein V. (278 aa)
	MORC2	MORC family CW-type zinc finger 2. (1032 aa)
	TNP1	Transition protein 1. (55 aa)
	H1-8	H1 histone family member O oocyte specific. (346 aa)
	HNRNPU	Heterogeneous nuclear ribonucleoprotein U. (806 aa)
	MTA1	Metastasis associated 1. (714 aa)
	KCNQ1	Potassium voltage-gated channel subfamily Q member 1; Belongs to the potassium channel family. (518 aa)
	IGF2	Insulin like growth factor 2. (236 aa)
	TRIM27	Tripartite motif containing 27. (513 aa)
	KDM1B	Lysine demethylase 1B. (822 aa)
	LMNB1	Lamin B1; Belongs to the intermediate filament family. (586 aa)
	ARID4A	AT-rich interaction domain 4A. (1006 aa)
	PABPC1L	Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (614 aa)
	PRDM14	PR/SET domain 14. (571 aa)
	LHX2	LIM homeobox 2. (406 aa)
	MACROH2A1	Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (368 aa)
	ARID1B	AT-rich interaction domain 1B. (1831 aa)
	HDAC6	Histone deacetylase 6. (1215 aa)
	AXIN1	Axin 1. (867 aa)
	JARID2	Jumonji and AT-rich interaction domain containing 2. (1246 aa)
	TASOR	Transcription activation suppressor. (1514 aa)
	BMI1	RING-type domain-containing protein. (449 aa)
	MBD3	Methyl-CpG binding domain protein 3. (291 aa)
	DOT1L	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1527 aa)
	ENSCSAP00000007796	H15 domain-containing protein. (342 aa)
	EPC1	Enhancer of polycomb homolog. (813 aa)
	LMNB2	Lamin B2; Belongs to the intermediate filament family. (621 aa)
	UBR2	E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1755 aa)
	SIRT6	Sirtuin 6. (355 aa)
	ZDBF2	Zinc finger DBF-type containing 2. (1992 aa)
	LOC103224842	Uncharacterized protein. (293 aa)
	HDAC1	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
	ARID1A	AT-rich interaction domain 1A. (2236 aa)
	PADI2	Peptidyl arginine deiminase 2. (665 aa)
	EXOSC10	Exosome component 10. (884 aa)
	CREBZF	CREB/ATF bZIP transcription factor. (354 aa)
	ENSCSAP00000017750	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (479 aa)
	ENSCSAP00000017863	GFA domain-containing protein. (245 aa)
	GLMN	Glomulin, FKBP associated protein. (625 aa)
	RBM15	RNA binding motif protein 15. (976 aa)
	LRIF1	Ligand dependent nuclear receptor interacting factor 1. (760 aa)
	VPS72	Vacuolar protein sorting 72 homolog. (364 aa)
	ENSCSAP00000016053	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (497 aa)
	LMNA	Lamin A/C; Belongs to the intermediate filament family. (663 aa)
	CHEK1	Checkpoint kinase 1. (749 aa)
	IFI16	Interferon gamma inducible protein 16. (728 aa)
	ENSCSAP00000017864	GFA domain-containing protein. (261 aa)
	CGGBP1	CGG triplet repeat binding protein 1. (167 aa)
	LOC103243499	Uncharacterized protein. (251 aa)
	RBM15B	RNA binding motif protein 15B. (890 aa)

Your Current Organism:

Chlorocebus sabaeus

NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID1A	ARID1B	ENSCSAP00000017030	ENSCSAP00000009399	AT-rich interaction domain 1A.	AT-rich interaction domain 1B.	0.983
ARID1A	EP300	ENSCSAP00000017030	ENSCSAP00000002153	AT-rich interaction domain 1A.	E1A binding protein p300.	0.544
ARID1A	EZH2	ENSCSAP00000017030	ENSCSAP00000003315	AT-rich interaction domain 1A.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.458
ARID1A	SMARCA5	ENSCSAP00000017030	ENSCSAP00000014603	AT-rich interaction domain 1A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5.	0.403
ARID1A	SMARCD1	ENSCSAP00000017030	ENSCSAP00000002292	AT-rich interaction domain 1A.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1.	0.993
ARID1B	ARID1A	ENSCSAP00000009399	ENSCSAP00000017030	AT-rich interaction domain 1B.	AT-rich interaction domain 1A.	0.983
ARID1B	EP300	ENSCSAP00000009399	ENSCSAP00000002153	AT-rich interaction domain 1B.	E1A binding protein p300.	0.440
ARID1B	SMARCD1	ENSCSAP00000009399	ENSCSAP00000002292	AT-rich interaction domain 1B.	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1.	0.972
ARID4A	ARID4B	ENSCSAP00000010551	ENSCSAP00000006309	AT-rich interaction domain 4A.	AT-rich interaction domain 4B.	0.624
ARID4A	ENSCSAP00000002484	ENSCSAP00000010551	ENSCSAP00000002484	AT-rich interaction domain 4A.	Uncharacterized protein.	0.597
ARID4A	ENSCSAP00000016053	ENSCSAP00000010551	ENSCSAP00000016053	AT-rich interaction domain 4A.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.914
ARID4A	ENSCSAP00000017750	ENSCSAP00000010551	ENSCSAP00000017750	AT-rich interaction domain 4A.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.914
ARID4A	EPC1	ENSCSAP00000010551	ENSCSAP00000007785	AT-rich interaction domain 4A.	Enhancer of polycomb homolog.	0.690
ARID4A	EZH2	ENSCSAP00000010551	ENSCSAP00000003315	AT-rich interaction domain 4A.	Enhancer of zeste 2 polycomb repressive complex 2 subunit.	0.410
ARID4A	GPX1	ENSCSAP00000010551	ENSCSAP00000011180	AT-rich interaction domain 4A.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.518
ARID4A	H3C11	ENSCSAP00000010551	ENSCSAP00000018587	AT-rich interaction domain 4A.	Histone H3; Belongs to the histone H3 family.	0.689
ARID4A	HDAC1	ENSCSAP00000010551	ENSCSAP00000016960	AT-rich interaction domain 4A.	Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.914
ARID4A	HDAC4	ENSCSAP00000010551	ENSCSAP00000002314	AT-rich interaction domain 4A.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.793
ARID4A	HDAC5	ENSCSAP00000010551	ENSCSAP00000014557	AT-rich interaction domain 4A.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.793
ARID4A	HDAC6	ENSCSAP00000010551	ENSCSAP00000009365	AT-rich interaction domain 4A.	Histone deacetylase 6.	0.793

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