STRINGSTRING
NOTCH1 NOTCH1 TBC1D32 TBC1D32 MSX1 MSX1 BCL2L11 BCL2L11 CTNNB1 CTNNB1 GNA12 GNA12 FREM2 FREM2 SMAD4 SMAD4 INTU INTU TMEM107 TMEM107 HAND2 HAND2 CHST11 CHST11 BAX BAX ZBTB16 ZBTB16 TBX3 TBX3 ENSCSAP00000016053 ENSCSAP00000016053 HDAC1 HDAC1 ECE1 ECE1 NOG NOG ENSCSAP00000017750 ENSCSAP00000017750 B9D1 B9D1 OSR1 OSR1 IHH IHH LRP5 LRP5 WNT7A WNT7A CREBBP CREBBP BMPR1A BMPR1A SFRP2 SFRP2 TULP3 TULP3 IFT140 IFT140 FZD6 FZD6 GRHL2 GRHL2 OSR2 OSR2 C2CD3 C2CD3 SALL1 SALL1 HOXC11 HOXC11 ALX4 ALX4 MKS1 MKS1 LRP4 LRP4 TBX2 TBX2 LMBR1 LMBR1 SHH SHH WNT5A WNT5A IFT52 IFT52 HOXA11 HOXA11 HOXD11 HOXD11 HOXD12 HOXD12 HOXD13 HOXD13 IMPAD1 IMPAD1 WDPCP WDPCP MAP3K20 MAP3K20 ENSCSAP00000010823 ENSCSAP00000010823 BMP4 BMP4 GLI3 GLI3 FLVCR1 FLVCR1 HDAC2 HDAC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NOTCH1Notch receptor 1. (2555 aa)
TBC1D32TBC1 domain family member 32. (968 aa)
MSX1Msh homeobox 1. (303 aa)
BCL2L11BCL2 like 11. (109 aa)
CTNNB1Catenin beta 1. (781 aa)
GNA12G protein subunit alpha 12. (305 aa)
FREM2FRAS1 related extracellular matrix 2. (2552 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
INTUInturned planar cell polarity protein. (921 aa)
TMEM107Transmembrane protein 107. (146 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
CHST11Carbohydrate sulfotransferase. (352 aa)
BAXBCL2 associated X, apoptosis regulator. (192 aa)
ZBTB16Zinc finger and BTB domain containing 16. (673 aa)
TBX3T-box transcription factor 3. (723 aa)
ENSCSAP00000016053Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (497 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (482 aa)
ECE1Endothelin converting enzyme 1. (754 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
ENSCSAP00000017750Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (479 aa)
B9D1B9 domain containing 1. (204 aa)
OSR1Odd-skipped related transcription factor 1. (266 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (411 aa)
LRP5LDL receptor related protein 5. (1451 aa)
WNT7AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
CREBBPCREB binding protein. (2417 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
TULP3Tubby-like protein; Belongs to the TUB family. (442 aa)
IFT140Intraflagellar transport 140. (1462 aa)
FZD6Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (706 aa)
GRHL2Grainyhead like transcription factor 2. (625 aa)
OSR2Odd-skipped related transciption factor 2. (276 aa)
C2CD3C2 domain containing 3 centriole elongation regulator. (2361 aa)
SALL1Spalt like transcription factor 1. (1321 aa)
HOXC11Homeobox C11. (304 aa)
ALX4ALX homeobox 4. (409 aa)
MKS1MKS transition zone complex subunit 1. (559 aa)
LRP4LDL receptor related protein 4. (1669 aa)
TBX2T-box transcription factor 2. (588 aa)
LMBR1Limb development membrane protein 1; Belongs to the LIMR family. (462 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (465 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa)
IFT52Intraflagellar transport 52. (442 aa)
HOXA11Homeobox A11. (310 aa)
HOXD11Homeobox D11. (338 aa)
HOXD12Homeobox D12. (270 aa)
HOXD13Homeobox D13. (343 aa)
IMPAD1Inositol monophosphatase domain containing 1. (359 aa)
WDPCPWD repeat containing planar cell polarity effector. (713 aa)
MAP3K20Protein kinase domain-containing protein. (292 aa)
ENSCSAP00000010823Protein kinase domain-containing protein. (169 aa)
BMP4Bone morphogenetic protein 4. (408 aa)
GLI3GLI family zinc finger 3. (1459 aa)
FLVCR1Feline leukemia virus subgroup C cellular receptor 1. (555 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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