node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGRN | APOE | ENSCSAP00000017336 | ENSCSAP00000014799 | Agrin. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.532 |
AGRN | LRP1 | ENSCSAP00000017336 | ENSCSAP00000001271 | Agrin. | LDL receptor related protein 1. | 0.658 |
AGRN | PTPRS | ENSCSAP00000017336 | ENSCSAP00000006208 | Agrin. | Protein tyrosine phosphatase receptor type S. | 0.631 |
APOE | AGRN | ENSCSAP00000014799 | ENSCSAP00000017336 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Agrin. | 0.532 |
APOE | ENSCSAP00000009714 | ENSCSAP00000014799 | ENSCSAP00000009714 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Uncharacterized protein. | 0.588 |
APOE | LPL | ENSCSAP00000014799 | ENSCSAP00000012759 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. | 0.913 |
APOE | LRP1 | ENSCSAP00000014799 | ENSCSAP00000001271 | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | LDL receptor related protein 1. | 0.976 |
COMP | ITGA2 | ENSCSAP00000001592 | ENSCSAP00000012702 | Cartilage oligomeric matrix protein. | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. | 0.710 |
ENSCSAP00000009714 | APOE | ENSCSAP00000009714 | ENSCSAP00000014799 | Uncharacterized protein. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.588 |
ITGA2 | COMP | ENSCSAP00000012702 | ENSCSAP00000001592 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. | Cartilage oligomeric matrix protein. | 0.710 |
ITGA2 | PTPRC | ENSCSAP00000012702 | ENSCSAP00000009830 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. | Protein tyrosine phosphatase receptor type C. | 0.480 |
LPL | APOE | ENSCSAP00000012759 | ENSCSAP00000014799 | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.913 |
LPL | LRP1 | ENSCSAP00000012759 | ENSCSAP00000001271 | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. | LDL receptor related protein 1. | 0.943 |
LRP1 | AGRN | ENSCSAP00000001271 | ENSCSAP00000017336 | LDL receptor related protein 1. | Agrin. | 0.658 |
LRP1 | APOE | ENSCSAP00000001271 | ENSCSAP00000014799 | LDL receptor related protein 1. | Apolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] | 0.976 |
LRP1 | LPL | ENSCSAP00000001271 | ENSCSAP00000012759 | LDL receptor related protein 1. | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. | 0.943 |
LRRTM4 | PTPRS | ENSCSAP00000011937 | ENSCSAP00000006208 | Leucine rich repeat transmembrane neuronal 4. | Protein tyrosine phosphatase receptor type S. | 0.581 |
PTPRC | ITGA2 | ENSCSAP00000009830 | ENSCSAP00000012702 | Protein tyrosine phosphatase receptor type C. | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. | 0.480 |
PTPRS | AGRN | ENSCSAP00000006208 | ENSCSAP00000017336 | Protein tyrosine phosphatase receptor type S. | Agrin. | 0.631 |
PTPRS | LRRTM4 | ENSCSAP00000006208 | ENSCSAP00000011937 | Protein tyrosine phosphatase receptor type S. | Leucine rich repeat transmembrane neuronal 4. | 0.581 |