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SLIT1 SLIT1 LRRTM3 LRRTM3 HPSE2 HPSE2 PTPRS PTPRS AZU1 AZU1 ENSCSAP00000009714 ENSCSAP00000009714 PTPRC PTPRC HRG HRG BMPER BMPER LRRTM4 LRRTM4 FST FST ITGA2 ITGA2 LPL LPL FGF20 FGF20 FBLN7 FBLN7 SEMA5A SEMA5A APOE APOE PLA2G2D PLA2G2D AGRN AGRN COMP COMP LRP1 LRP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SLIT1Slit guidance ligand 1. (1396 aa)
LRRTM3Leucine rich repeat transmembrane neuronal 3. (513 aa)
HPSE2Uncharacterized protein. (120 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1941 aa)
AZU1Azurocidin 1; Belongs to the peptidase S1 family. (253 aa)
ENSCSAP00000009714Uncharacterized protein. (1359 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1309 aa)
HRGHistidine rich glycoprotein. (521 aa)
BMPERBMP binding endothelial regulator. (685 aa)
LRRTM4Leucine rich repeat transmembrane neuronal 4. (518 aa)
FSTFollistatin. (344 aa)
ITGA2Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1180 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (475 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
FBLN7Fibulin 7. (439 aa)
SEMA5ASemaphorin 5A. (1074 aa)
APOEApolipoprotein E; APOE is an apolipoprotein, a protein associating with lipid particles, that mainly functions in lipoprotein-mediated lipid transport between organs via the plasma and interstitial fluids. APOE is a core component of plasma lipoproteins and is involved in their production, conversion and clearance. Apoliproteins are amphipathic molecules that interact both with lipids of the lipoprotein particle core and the aqueous environment of the plasma. As such, APOE associates with chylomicrons, chylomicron remnants, very low density lipoproteins (VLDL) and intermediate density [...] (317 aa)
PLA2G2DPhospholipase A(2). (161 aa)
AGRNAgrin. (2067 aa)
COMPCartilage oligomeric matrix protein. (757 aa)
LRP1LDL receptor related protein 1. (4544 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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