STRINGSTRING
EME2 EME2 ETAA1 ETAA1 WDHD1 WDHD1 MMS22L MMS22L POLA1 POLA1 RPA1 RPA1 PRIM2 PRIM2 PCNA PCNA MCM10 MCM10 TIPIN TIPIN RPA3 RPA3 POLD2 POLD2 SMARCAL1 SMARCAL1 POLD4 POLD4 TONSL TONSL POLA2 POLA2 TIMELESS TIMELESS SMARCAD1 SMARCAD1 POLD3 POLD3 ENSCSAP00000017472 ENSCSAP00000017472 RPA2 RPA2 POLD1 POLD1 ENSCSAP00000014778 ENSCSAP00000014778 ZRANB3 ZRANB3 ZMIZ2 ZMIZ2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EME2Essential meiotic structure-specific endonuclease subunit 2. (383 aa)
ETAA1ETAA1 activator of ATR kinase. (898 aa)
WDHD1WD repeat and HMG-box DNA binding protein 1. (1104 aa)
MMS22LMMS22 like, DNA repair protein. (1243 aa)
POLA1DNA polymerase. (1465 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (557 aa)
PRIM2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (509 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
MCM10Minichromosome maintenance 10 replication initiation factor. (874 aa)
TIPINTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (307 aa)
RPA3Replication protein A3. (121 aa)
POLD2DNA polymerase delta 2, accessory subunit. (469 aa)
SMARCAL1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (949 aa)
POLD4Uncharacterized protein. (107 aa)
TONSLTonsoku like, DNA repair protein. (1377 aa)
POLA2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (598 aa)
TIMELESSTimeless circadian regulator. (1208 aa)
SMARCAD1Uncharacterized protein. (840 aa)
POLD3Uncharacterized protein. (466 aa)
ENSCSAP00000017472ERCC4 domain-containing protein. (551 aa)
RPA2Replication protein A2. (270 aa)
POLD1DNA polymerase. (1086 aa)
ENSCSAP00000014778RPA_C domain-containing protein. (256 aa)
ZRANB3Zinc finger RANBP2-type containing 3. (1016 aa)
ZMIZ2Zinc finger MIZ-type containing 2. (920 aa)
Your Current Organism:
Chlorocebus sabaeus
NCBI taxonomy Id: 60711
Other names: C. sabaeus, Cercopithecus aethiops sabaeus, Cercopithecus sabaeus, Cercopithecus sabeus, Chlorocebus aethiops sabaeus, Chlorocebus aethiops sabeus, Chlorocebus sabeus, green monkey
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